Friday, July 10, 2026

Drug profile · INN

s-ketamine

s-ketamine is a glutamate [nmda] receptor negative allosteric modulator.

NMPA: clinical trials
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — s-ketamine
Class
Route
Patents
0
Programs
5
Data quality
0.70

Quick answer

s-ketamine is a glutamate [nmda] receptor negative allosteric modulator.

Key facts

INN s-ketamine
Mechanism Glutamate [NMDA] receptor negative allosteric modulator
Target Glutamate [NMDA] receptor

Mechanism of action

Glutamate [NMDA] receptor negative allosteric modulator

Primary target: Glutamate [NMDA] receptor

Approval history

Authority Status Date
NMPA clinical trials

Pipeline programs

  1. Conventional therapy + S (+)-Ketamine Approved · Chinese Academy of · S-ketamine
  2. S-ketamine & Ropivacaine Approved · First People's Hospital · Postoperative Analgesia
  3. S-ketamine Unknown · Chinese Academy of · Anesthesia
  4. S-ketamine Unknown · Zenshine Pharmaceuticals · Opioid Use, Unspecified
  5. S-ketamine Unknown · First People's Hospital · Opioid Use, Unspecified

Related & competitor drugs

  1. amantadine hydrochloride Glutamate [NMDA] receptor antagonist
  2. felbamate Glutamate [NMDA] receptor antagonist
  3. memantine hydrochloride Nervous system (N06)
  4. esketamine hydrochloride Glutamate [NMDA] receptor negative allosteric modulator
  5. ketamine hydrochloride Glutamate [NMDA] receptor negative allosteric modulator
  6. orphenadrine citrate Norepinephrine transporter inhibitor

Frequently asked questions

What is s-ketamine?

s-ketamine is a glutamate [nmda] receptor negative allosteric modulator.