Wednesday, July 8, 2026

Drug profile · INN

memantine hydrochloride

memantine hydrochloride (MEMANTINE MERZ) is a glutamate [nmda] receptor negative allosteric modulator. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved PMDA: approved Nervous system (N06) N06DX01
US status approved
Patents linked 1
Pipeline programs 0
News articles 0
Drug details — memantine hydrochloride
US status
approved
Class
Nervous system (N06)
Route
ORAL
Patents
1
Programs
0
Data quality
0.89

Quick answer

memantine hydrochloride (MEMANTINE MERZ) is a glutamate [nmda] receptor negative allosteric modulator. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN memantine hydrochloride
Brand MEMANTINE MERZ
Mechanism Glutamate [NMDA] receptor negative allosteric modulator
Target Glutamate [NMDA] receptor
Therapeutic class Nervous system (N06)
Route ORAL
Formulation SOLUTION
ATC code N06DX01

Mechanism of action

Glutamate [NMDA] receptor negative allosteric modulator

Primary target: Glutamate [NMDA] receptor

Approval history

Authority Status Date
FDA approved
EMA approved
PMDA approved

Related & competitor drugs

  1. amantadine hydrochloride Glutamate [NMDA] receptor antagonist
  2. aripiprazole Nervous system (N05)
  3. brexpiprazole Nervous system (N05)
  4. brivaracetam Nervous system (N03)
  5. bupivacaine Nervous system (N01)
  6. buprenorphine Nervous system (N07)
  1. US 7462743

    Polymorphs of memantine hydrochloride

    Expires Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is memantine hydrochloride?

memantine hydrochloride (MEMANTINE MERZ) is a glutamate [nmda] receptor negative allosteric modulator. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for memantine hydrochloride?

MEMANTINE MERZ is a marketed brand name for memantine hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of memantine hydrochloride?

memantine hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.