Wednesday, July 8, 2026

Drug profile · INN

amantadine hydrochloride

amantadine hydrochloride (AMANTADINE HYDROCHLORIDE) is a glutamate [nmda] receptor antagonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 1
News articles 0
Drug details — amantadine hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
1
Data quality
0.89

Quick answer

amantadine hydrochloride (AMANTADINE HYDROCHLORIDE) is a glutamate [nmda] receptor antagonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN amantadine hydrochloride
Brand AMANTADINE HYDROCHLORIDE
Mechanism Glutamate [NMDA] receptor antagonist
Target Glutamate [NMDA] receptor
Route ORAL
Formulation CAPSULE

Mechanism of action

Glutamate [NMDA] receptor antagonist

Primary target: Glutamate [NMDA] receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Gocovri (extended-release amantidine) Phase 2 · SUPERNUS PHARMACEUTICALS · Radiation Encephalopathy

Related & competitor drugs

  1. felbamate Glutamate [NMDA] receptor antagonist
  2. memantine hydrochloride Nervous system (N06)
  3. esketamine hydrochloride Glutamate [NMDA] receptor negative allosteric modulator
  4. ketamine hydrochloride Glutamate [NMDA] receptor negative allosteric modulator
  5. orphenadrine citrate Norepinephrine transporter inhibitor
  6. orphenadrine hydrochloride Norepinephrine transporter inhibitor

Frequently asked questions

What is amantadine hydrochloride?

amantadine hydrochloride (AMANTADINE HYDROCHLORIDE) is a glutamate [nmda] receptor antagonist. Associated with Teva Pharma GmbH. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for amantadine hydrochloride?

AMANTADINE HYDROCHLORIDE is a marketed brand name for amantadine hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of amantadine hydrochloride?

amantadine hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.