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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 93 of 99

  1. [14C-ETC-1002]

    Esperion Therapeutics

    Hyperlipidemia

    phase 1 small molecule completed

    1 trial

  2. [14C] Antaitavir Hasophate

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Male Subjects

    phase 1 small molecule completed

    1 trial

  3. [14C] BIIB122 ([14C] DNL151)

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  4. [14C] HRS-9190

    Jian Li

    Healthy Adult Male

    phase 1 small molecule active

    1 trial

  5. [14C] Subasumstat

    Takeda

    Solid Tumors

    phase 1 small molecule terminated

    1 trial

  6. [14C] Yiqibuvir

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Male Subjects

    phase 1 small molecule completed

    1 trial

  7. [14C]- Rongliflozin

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Male Volunteers

    phase 1 small molecule completed

    1 trial

  8. [14C]-AG-120

    Agios Netherlands B.V.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  9. [14C]-CORT113176

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  10. [14C]-CORT125134

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  11. [14C]-CRN00808

    Crinetics Pharmaceuticals Europe GmbH

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  12. [14C]-DNL343

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  13. [14C]-Danicopan

    Alexion Europe SAS

    Healthy

    phase 1 small molecule completed

    1 trial

  14. [14C]-EDG-7500

    Edgewise Therapeutics

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  15. [14C]-GSK961081 solution for IV infusion

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    1 trial

  16. [14C]-HEC585

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  17. [14C]-LX4211

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  18. [14C]-Larotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Male Volunteers

    phase 1 small molecule completed

    1 trial

  19. [14C]-NV-5138

    SUPERNUS PHARMACEUTICALS, INC.

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  20. [14C]-PC14586

    PMV Pharmaceuticals

    Healthy Male Volunteers

    phase 1 small molecule completed

    1 trial

  21. [14C]-Paxalisib Capsule

    KAZIA THERAPEUTICS LTD

    Healthy

    phase 1 small molecule completed

    1 trial

  22. [14C]-TAK-385 Oral Solution

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  23. [14C]-TAK-954

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  24. [14C]-TVB-2640

    Sagimet Biosciences

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  25. [14C]-benzo[a]pyrene

    NORTHWEST BIOTHERAPEUTICS INC

    Environmental Exposure

    phase 1 small molecule completed

    3 trials

  26. [14C]-etrumadenant

    Arcus Biosciences

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  27. [14C]-olinciguat

    Cyclerion Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  28. [14C]-praliciguat

    Cyclerion Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  29. [14C]-rencofilstat 225mg

    Hepion Pharmaceuticals

    NASH With Fibrosis

    phase 1 small molecule completed

    1 trial

  30. [14C]-tebapivat

    Agios Netherlands B.V.

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  31. [14C]Clifutinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Male

    phase 1 small molecule completed

    1 trial

  32. [14C]HSK7653

    The First People's Hospital of Lianyungang

    Type II Diabetes

    phase 1 small molecule completed

    1 trial

  33. [14C]IDV184001AN

    Indivior Pty Ltd

    Opioid Use Disorder

    phase 1 small molecule completed

    1 trial

  34. [14C]SSS17

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Subjects (HS)

    phase 1 small molecule active

    1 trial

  35. [14C]TGRX-326

    The First People's Hospital of Lianyungang

    Non Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  36. [177Lu]Lu-XT117

    The First People's Hospital of Lianyungang

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  37. [18F]-αvβ6-BP

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 1 small molecule active

    1 trial

  38. [18F]APN-1607

    The First People's Hospital of Lianyungang

    Alzheimer Disease

    phase 1 small molecule active

    1 trial

  39. [18F]F-AraG

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cancer

    phase 1 small molecule active

    1 trial

  40. [18F]FP-R01-MG-F2

    PLIANT THERAPEUTICS, INC.

    Idiopathic Pulmonary Fibrosis

    phase 1 small molecule completed

    1 trial

  41. [18F]fluoro-PEG-folate PET/CT scan

    BRIGHT MINDS BIOSCIENCES INC.

    Epithelial Ovarian Cancer

    phase 1 other terminated

    1 trial

  42. [203Pb]VMT-α-NET

    Perspective Therapeutics

    Neuroendocrine Tumor Grade 2

    phase 1 small molecule active

    1 trial

  43. [203Pb]VMT01

    Perspective Therapeutics

    Melanoma (Skin)

    phase 1 small molecule completed

    1 trial

  44. [212Pb] VMT-α-NET

    Perspective Therapeutics

    Neuroendocrine Tumors

    phase 1 small molecule active

    1 trial

  45. [225Ac]Ac-AKY-1189 (therapeutic)

    Aktis Oncology

    Urothelial Carcinoma Bladder

    phase 1 small molecule active

    1 trial

  46. [225Ac]Ac-AKY-2519 (therapeutic)

    Aktis Oncology

    Castration Resistant Metastatic Prostate Cancer

    phase 1 small molecule active

    1 trial

  47. [68Ga]Ga-PentixaFor

    CERO THERAPEUTICS HOLDINGS, INC.

    triple-negative breast cancer

    phase 1 small molecule active

    1 trial

  48. [68Ga]Ga-Sa-DABI-4

    The First People's Hospital of Lianyungang

    Stimulator of Interferon Gene

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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