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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 92 of 99

  1. Yiqi Wenyang Sanhan Formula Combined with Acupoint Application

    Universal Integrated

    Allergic Rhinitis With Asthma

    phase 1 small molecule active

    1 trial

  2. Yohimbine Hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Cigarette Smoking

    phase 1 small molecule completed

    1 trial

  3. Z-1018

    Dynavax International B.V.

    Shingles

    phase 1 mab completed

    1 trial

  4. Z650

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Pancreatic Cancer

    phase 1 small molecule terminated

    1 trial

  5. ZB001 for injection

    Zenas BioPharma

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  6. ZB001 for injection

    Zenas BioPharma

    Thyroid Eye Disease

    phase 1 small molecule completed

    1 trial

  7. ZB002

    Zenas BioPharma

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  8. ZB004

    Zenas BioPharma

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  9. ZE46-0134

    Lomond Therapeutics Holdings

    AML With Gene Mutations

    phase 1 small molecule active

    1 trial

  10. ZF874

    Centessa Pharmaceuticals plc

    Alpha1 Anti-Trypsin Deficiency

    phase 1 small molecule terminated

    1 trial

  11. ZFN modified T cells

    SANGAMO THERAPEUTICS, INC

    HIV

    phase 1 mab completed

    1 trial

  12. ZG0895 Hydrochloride for Injection

    Suzhou Zelgen Biopharmaceuticals Co.,Ltd

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  13. ZIO-101

    Alaunos Therapeutics

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  14. ZIO-101 (Darinaparsin)

    Alaunos Therapeutics

    Acute Leukemia

    phase 1 small molecule completed

    1 trial

  15. ZIO-101 (Darinaparsin)

    Alaunos Therapeutics

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  16. ZIO-101-C (Darinaparsin)

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  17. ZIO-101-C (Darinaparsin)

    Alaunos Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  18. ZIO-201

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  19. ZIO-201-T and doxorubicin

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  20. ZN-c3

    Zentalis Pharmaceuticals

    Metastatic Colorectal Cancer

    phase 1 small molecule terminated

    1 trial

  21. ZN-c3

    Zentalis Pharmaceuticals

    Tumors

    phase 1 small molecule terminated

    1 trial

  22. ZN-d5

    Zentalis Pharmaceuticals

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  23. ZN-d5

    Zentalis Pharmaceuticals

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  24. ZP7570-24026

    Zealand Pharma A/S

    Weight management

    phase 1 other active

    1 trial

  25. ZP8396-24059

    Zealand Pharma A/S

    Weight management

    phase 1 other active

    1 trial

  26. ZP8396-25041

    Zealand Pharma A/S

    Weight reduction

    phase 1 other active

    1 trial

  27. ZP8396-25077

    Zealand Pharma A/S

    Healthy / hepatic impaired volunteers only study to assess PK parameters

    phase 1 other active

    1 trial

  28. ZW25 (Zanidatamab)

    Jazz Pharmaceuticals Ireland Limited

    HER2-expressing Cancers

    phase 1 small molecule completed

    1 trial

  29. Zaleplon 10 mg Capsules

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  30. Zanubrutinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Lymphocytic Leukemia

    phase 1 small molecule active

    1 trial

  31. Zasocitinib

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  32. Ziftomenib

    Kura Oncology

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  33. Ziftomenib

    Kura Oncology

    Refractory Acute Leukemia

    phase 1 small molecule active

    1 trial

  34. Ziftomenib

    Kura Oncology

    KMT2A-rearranged

    phase 1 small molecule active

    1 trial

  35. Ziftomenib

    Kura Oncology

    Relapsed/Refractory KMT2A-r Acute Leukemia

    phase 1 small molecule active

    1 trial

  36. Ziftomenib

    Kura Oncology

    AML

    phase 1 small molecule active

    1 trial

  37. Ziftomenib for Acute Myeloid Leukemia, Mixed P…

    AXIM BIOTECHNOLOGIES, INC.

    Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Acute Lymphocytic Leukemia

    phase 1 small molecule active

    1 trial

  38. Zimberelimab

    Arcus Biosciences

    Head and Neck Cancer

    phase 1 small molecule terminated

    1 trial

  39. Zimberelimab

    Arcus Biosciences

    Glioblastoma

    phase 1 small molecule active

    1 trial

  40. Zithromax®

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  41. Zolmitriptan intranasal.

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  42. Zoloft® 100 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  43. Zolpidem 10 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  44. Zunsemetinib

    Aclaris Therapeutics

    Metastatic Pancreatic Ductal Adenocarcinoma

    phase 1 small molecule active

    1 trial

  45. [11C]APP311

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use Disorder

    phase 1 small molecule active

    1 trial

  46. [11C]CPPC Injection

    Chongqing Precision Biotech Co., Ltd

    Amyotrophic Lateral Sclerosis

    phase 1 small molecule terminated

    1 trial

  47. [11C]OMAR

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Control

    phase 1 small molecule active

    1 trial

  48. [123I] IBVM and SPECT imaging

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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