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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 89 of 99

  1. VHX-896 and iloperidone

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy

    phase 1 small molecule completed

    1 trial

  2. VIR-1111

    Vir Biotechnology

    HIV I Infection

    phase 1 mab completed

    1 trial

  3. VIR-2218

    Vir Biotechnology

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  4. VIR-2218

    Vir Biotechnology

    Hepatic Impairment

    phase 1 small molecule active

    1 trial

  5. VIR-2482

    Vir Biotechnology

    Influenza A

    phase 1 small molecule completed

    1 trial

  6. VIR-3434

    Vir Biotechnology

    Chronic Hepatitis B

    phase 1 mab completed

    1 trial

  7. VIR-5500

    Vir Biotechnology

    Hormone-refractory Prostate Cancer

    phase 1 small molecule active

    1 trial

  8. VIR-5525

    Vir Biotechnology

    Solid Tumor Malignancies

    phase 1 small molecule active

    1 trial

  9. VIR-5818-V101

    Vir Biotechnology

    Participants with Locally Advanced or Metastatic HER2-Expressing Cancers

    phase 1 other active

    1 trial

  10. VIS171-103

    Otsuka Beijing Research Institute

    Systemic lupus erythematosus, Immune-mediated focal segmental glomerulosclerosis, Alopecia Areata

    phase 1 other active

    1 trial

  11. VK0214

    Viking Therapeutics

    Adrenomyeloneuropathy Form (AMN) of X-linked Adrenoleukodystrophy (X-ALD)

    phase 1 small molecule completed

    1 trial

  12. VK4-116

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Dependence

    phase 1 small molecule active

    1 trial

  13. VLY-686

    Vanda Pharmaceuticals Netherlands B.V.

    Pruritus

    phase 1 small molecule completed

    1 trial

  14. VP 20629

    Takeda

    Friedreich's Ataxia

    phase 1 small molecule completed

    1 trial

  15. VP-C21-014

    Lacuna Pharma Pty Ltd

    Idiopahtic pulmonary fibrosis

    phase 1 other active

    1 trial

  16. VP-C21-016

    Lacuna Pharma Pty Ltd

    Idiopathic pulmonary fibrosis

    phase 1 other active

    1 trial

  17. VP-VTR-297-1101

    Lacuna Pharma Pty Ltd

    relapsed/refractory hematologic malignancies

    phase 1 other active

    1 trial

  18. VPH-GXL-2025-1

    Lacuna Pharma Pty Ltd

    Hypolactasia

    phase 1 other active

    1 trial

  19. VRON-0200-AdC6

    Vir Biotechnology

    Chronic Hepatitis B

    phase 1 mab active

    1 trial

  20. VS-6766

    United Therapeutics Europe Ltd

    NSCLC

    phase 1 small molecule active

    1 trial

  21. VSA001 injection

    Arrowhead Pharmaceuticals Ireland Limited

    Healthy Adult Volunteers

    phase 1 small molecule completed

    1 trial

  22. VTP-1000

    Barinthus Biotherapeutics plc.

    Celiac Disease

    phase 1 mab active

    1 trial

  23. VV261 5mg group

    Vigonvita Life Sciences

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  24. VX-118

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 1 small molecule completed

    1 trial

  25. VX-147

    Vertex Pharmaceuticals (Australia) Pty.

    Focal Segmental Glomerulosclerosis (FSGS)

    phase 1 small molecule completed

    1 trial

  26. VX-150

    Vertex Pharmaceuticals (Australia) Pty.

    Pain

    phase 1 small molecule completed

    1 trial

  27. VX-272

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 1 small molecule active

    1 trial

  28. VX-433

    Vertex Pharmaceuticals (Australia) Pty.

    Narcolepsy Type 1 (NT1)

    phase 1 small molecule active

    1 trial

  29. VX-440

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 1 small molecule completed

    1 trial

  30. VX-509

    Vertex Pharmaceuticals (Australia) Pty.

    Healthy

    phase 1 small molecule completed

    1 trial

  31. VX-548

    Vertex Pharmaceuticals (Australia) Pty.

    Pain

    phase 1 small molecule completed

    7 trials

  32. VX-581

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 1 small molecule active

    1 trial

  33. VX-634

    Vertex Pharmaceuticals (Australia) Pty.

    Alpha 1-Antitrypsin Deficiency

    phase 1 small molecule completed

    1 trial

  34. VX-668

    Vertex Pharmaceuticals (Australia) Pty.

    Alpha-1 Antitrypsin Deficiency

    phase 1 small molecule completed

    1 trial

  35. VX-708

    Vertex Pharmaceuticals (Australia) Pty.

    Acute Pain

    phase 1 small molecule completed

    1 trial

  36. VX-708

    Vertex Pharmaceuticals (Australia) Pty.

    Pain

    phase 1 small molecule completed

    1 trial

  37. VX-770

    Vertex Pharmaceuticals (Australia) Pty.

    In Development for Cystic Fibrosis

    phase 1 small molecule completed

    2 trials

  38. VX-828

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 1 small molecule active

    2 trials

  39. VX-840

    Vertex Pharmaceuticals (Australia) Pty.

    APOL1-mediated Kidney Disease

    phase 1 small molecule completed

    1 trial

  40. VX-973

    Vertex Pharmaceuticals (Australia) Pty.

    Pain

    phase 1 small molecule completed

    2 trials

  41. VX-985 or matching placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 1 small molecule completed

    1 trial

  42. VX-993

    Vertex Pharmaceuticals (Australia) Pty.

    Pain

    phase 1 small molecule completed

    6 trials

  43. VX15/2503

    VACCINEX, INC.

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  44. VX15/2503

    VACCINEX, INC.

    Squamous Cell Carcinoma of the Head and Neck

    phase 1 mab active

    1 trial

  45. VX15/2503

    VACCINEX, INC.

    Multiple Sclerosis

    phase 1 small molecule completed

    1 trial

  46. VY-AADC01

    NEUROCRINE BIOSCIENCES INC

    Idiopathic Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  47. VY-AADC01

    NEUROCRINE BIOSCIENCES INC

    Parkinson's Disease

    phase 1 mab completed

    1 trial

  48. VY-AADC02

    NEUROCRINE BIOSCIENCES INC

    Parkinson's Disease

    phase 1 mab completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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