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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 88 of 99

  1. UI059

    United Therapeutics Europe Ltd

    GERD

    phase 1 small molecule completed

    1 trial

  2. UI059

    United Therapeutics Europe Ltd

    Gastro-Intestinal Disorder

    phase 1 small molecule active

    1 trial

  3. UI15AML055MT

    United Therapeutics Europe Ltd

    Healthy

    phase 1 small molecule completed

    1 trial

  4. UIC201602 and co-administration of UIC201601 and UIC201602

    United Therapeutics Europe Ltd

    Healthy

    phase 1 small molecule completed

    1 trial

  5. UKidney

    United Therapeutics Europe Ltd

    Kidney Failure, Chronic

    phase 1 other terminated

    1 trial

  6. UMCG-NEOLYNC-001

    Disc Medicine

    Cervical Cancer

    phase 1 other active

    1 trial

  7. UNEX-42

    United Therapeutics Europe Ltd

    Bronchopulmonary Dysplasia

    phase 1 mab terminated

    1 trial

  8. UP0122

    Lacuna Pharma Pty Ltd

    Hidradenitis suppurativa, Axial spondyloarthritis, Moderate to Severe Plaque Psoriasis, Psoriatic arthritis

    phase 1 small molecule active

    1 trial

  9. UP0124

    Lacuna Pharma Pty Ltd

    Healthy Participants

    phase 1 other active

    1 trial

  10. UP421

    Sana Biotechnology

    Type1diabetes

    phase 1 mab active

    1 trial

  11. UPADA-01-24

    Lacuna Pharma Pty Ltd

    Rheumatoid arthritis, ulcerative colitis, atopic dermatitis, Crohn's disease, psoriatic arthritis, axial spondyloarthritis

    phase 1 other active

    1 trial

  12. UPADA-02-24

    Lacuna Pharma Pty Ltd

    Axial spondyloarthritis, Crohn’s disease, Ulcerative colitis, Atopic dermatitis, Rheumatoid arthritis, Psoriatic arthritis

    phase 1 other active

    1 trial

  13. UPADA-03-24

    Lacuna Pharma Pty Ltd

    Rheumatoid arthritis, ulcerative colitis, atopic dermatitis, Crohn's disease, psoriatic arthritis, axial spondyloarthritis

    phase 1 other active

    1 trial

  14. UR001

    Lacuna Pharma Pty Ltd

    Non-muscle Invasive Bladder Cancer

    phase 1 other active

    1 trial

  15. USB005 (aclerastide) Ophthalmic Solution

    United Therapeutics Europe Ltd

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  16. UT-15C

    United Therapeutics Europe Ltd

    Healthy

    phase 1 small molecule completed

    2 trials

  17. UT-15C SR (treprostinil diethanolamine)

    United Therapeutics Europe Ltd

    Pulmonary Arterial Hypertension

    phase 1 small molecule completed

    1 trial

  18. UTAA09 injection

    The First People's Hospital of Lianyungang

    Recurrent or Refractory B-cell Non Hodgkin's Lymphoma

    phase 1 mab active

    1 trial

  19. UTAA91 injection

    Suzhou Ribo Life Science Co.

    Rheumatoid Arthritis (RA)

    phase 1 mab active

    1 trial

  20. UTAA91 injection

    Hospital Authority, Hong Kong

    Rheumatoid Arthritis (RA)

    phase 1 mab active

    1 trial

  21. UX-GIP001

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Epilepsy

    phase 1 small molecule active

    1 trial

  22. Ublituximab + TGR-1202

    TG THERAPEUTICS, INC.

    Chronic Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  23. Unesbulin

    PTC THERAPEUTICS, INC.

    Ovarian Cancer

    phase 1 small molecule completed

    1 trial

  24. Ursodiol

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  25. V920

    United Therapeutics Europe Ltd

    Ebola Virus

    phase 1 mab completed

    1 trial

  26. V930

    INOVIO PHARMACEUTICALS, INC.

    Healthy

    phase 1 mab completed

    1 trial

  27. VAR2-2024-CS01

    Lacuna Pharma Pty Ltd

    Multiple solid tumors including: colorectal carcinoma (CRC), pancreatic carcinoma, oesophageal or gastric carcinoma, head and neck squamous cell carcinoma (HNSCC), chondrosarcoma or osteosarcoma, bladder carcinoma, lung carcinoma and glioblastoma.

    phase 1 other active

    1 trial

  28. VCH 916

    Vertex Pharmaceuticals (Australia) Pty.

    HCV Infection

    phase 1 small molecule completed

    1 trial

  29. VCH-222

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 1 small molecule completed

    1 trial

  30. VCTX210A unit

    S.A.

    Diabetes Mellitus

    phase 1 other completed

    1 trial

  31. VCTX211

    S.A.

    Diabetes Mellitus

    phase 1 other terminated

    1 trial

  32. VE-CIP1002/2021

    Alfasigma S.p.A.

    chronic intestinal pseudo-obstruction (CIPO)

    phase 1 other active

    1 trial

  33. VEGF Trap

    Regeneron UK Limited

    Neovascular Age Related Macular Degeneration

    phase 1 small molecule completed

    1 trial

  34. VEGF Trap

    Regeneron UK Limited

    Macular Degeneration

    phase 1 small molecule completed

    1 trial

  35. VEGF Trap-Eye

    Regeneron UK Limited

    Diabetic Macular Edema

    phase 1 small molecule completed

    1 trial

  36. VEGF inhibitor PTC299

    PTC THERAPEUTICS, INC.

    Brain and Central Nervous System Tumors

    phase 1 small molecule completed

    1 trial

  37. VGB-R04

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hemophilia B

    phase 1 gene therapy active

    1 trial

  38. VGX-3100

    INOVIO PHARMACEUTICALS, INC.

    Human Papillomavirus (HPV)

    phase 1 mab completed

    1 trial

  39. VGX-3100

    INOVIO PHARMACEUTICALS, INC.

    Papillomavirus Infections

    phase 1 mab completed

    1 trial

  40. VGX-3400

    INOVIO PHARMACEUTICALS, INC.

    Healthy

    phase 1 mab completed

    1 trial

  41. VGX-3400X

    INOVIO PHARMACEUTICALS, INC.

    Healthy

    phase 1 mab completed

    1 trial

  42. VGX-6150

    INOVIO PHARMACEUTICALS, INC.

    Hepatitis C, Chronic

    phase 1 mab completed

    1 trial

  43. VHIO20001

    The George Institute

    Advanced epithelial tumors and immune checkpoint blockade (ICB) resistant solid tumors

    phase 1 other active

    1 trial

  44. VHIO20002

    The George Institute

    Refractory metastatic Her2 positive breast cancer

    phase 1 other active

    1 trial

  45. VHIO24001

    The George Institute

    Locally advanced, recurrent, or metastatic breast, gastric, endometrial, and selected other solid tumors with positive expression for HER-2 (3+)

    phase 1 other active

    1 trial

  46. VHIO24001

    The George Institute

    Locally advanced, recurrent, or metastatic breast, gastric, endometrial, and selected other solid tumors with positive expression for HER-2 (3+)

    phase 1 other active

    1 trial

  47. VHX-896

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy

    phase 1 small molecule completed

    1 trial

  48. VHX-896 and iloperidone

    Vanda Pharmaceuticals Netherlands B.V.

    Schizophrenia

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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