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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 87 of 99

  1. Trastuzumab

    Hoffmann-La Roche

    Early Breast Cancer

    phase 1 small molecule completed

    1 trial

  2. Trastuzumab Deruxtecan

    Daiichi Sankyo

    Recurrent or Metastatic Solid Tumors

    phase 1 small molecule active

    1 trial

  3. Treatment A

    Tonix Pharmaceuticals Holding

    Healthy

    phase 1 small molecule completed

    1 trial

  4. Treatment A

    Tonix Pharmaceuticals Holding

    Healthy Adults

    phase 1 small molecule completed

    1 trial

  5. Treatment A

    Pfizer

    Asthma

    phase 1 small molecule completed

    1 trial

  6. Treatment A

    Pfizer

    Healthy

    phase 1 small molecule completed

    1 trial

  7. Treatment A (rosuvastatin)

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  8. Treatment A digoxin

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  9. Treatment A-Bemnifosbuvir/Ruzasvir FDC administered fasting

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  10. Treatment A: Fp MDPI

    Teva Pharma GmbH

    Asthma

    phase 1 small molecule completed

    1 trial

  11. Treatment as usual (TAU)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Abuse

    phase 1 other completed

    1 trial

  12. Treatment sequence AB

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 1 small molecule completed

    1 trial

  13. Trebananib 3 mg/kg

    Takeda

    Neoplasms, Advanced Solid

    phase 1 small molecule completed

    1 trial

  14. Treprostinil Inhalation Powder

    United Therapeutics Europe Ltd

    Pulmonary Arterial Hypertension

    phase 1 small molecule completed

    1 trial

  15. Treprostinil diethanolamine

    United Therapeutics Europe Ltd

    Hypertension, Pulmonary

    phase 1 small molecule completed

    2 trials

  16. Trial of the novel peroral anti-tumor treatment in patients with solid tumors

    Lacuna Pharma Pty Ltd

    Metastatic or locally advanced solid tumors for which no standard therapy exists or standard therapy has failed: tumors of lung, head and neck, colon, stomach, esophagus, breast, ovary and/or fallopian tube or primary peritoneal high-grade serous carcinoma

    phase 1 other active

    1 trial

  17. Triamcinolone Acetonide Extended-Release Injectable Suspension

    Pacira Ireland Limited

    Osteoarthritis, Knee

    phase 1 small molecule completed

    1 trial

  18. Trichostatin A

    Vanda Pharmaceuticals Netherlands B.V.

    Relapsed or Refractory Hematologic Malignancies

    phase 1 small molecule active

    1 trial

  19. Triheptanoin

    Ultragenyx UK Limited

    Pyruvate Dehydrogenase Complex Deficiency

    phase 1 small molecule active

    1 trial

  20. Triheptanoin

    Ultragenyx UK Limited

    Glycogen Storage Disease Type I

    phase 1 small molecule completed

    1 trial

  21. Triprorelin for injection

    The First People's Hospital of Lianyungang

    Prostate Cancer (CRPC)

    phase 1 small molecule active

    1 trial

  22. Tuberculosis (TB) vaccine (Ad5-105K)

    CanSino Biologics

    Tuberculosis

    phase 1 mab active

    1 trial

  23. Tuberculosis Vaccine

    Biotech Pharmaceutical Co.,

    Tuberculosis

    phase 1 mab completed

    1 trial

  24. U10-02-11-001

    PDS Biotechnology Corp

    High-risk HPV Infection and Biopsy-proven CIN1

    phase 1 mab completed

    1 trial

  25. U96

    The First People's Hospital of Lianyungang

    Relapsed or Refractory B Cell Leukemia and Lymphoma

    phase 1 small molecule active

    1 trial

  26. UB-221

    United Therapeutics Europe Ltd

    Urticaria Chronic

    phase 1 mab completed

    1 trial

  27. UB-221

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Spontaneous Urticaria

    phase 1 mab active

    1 trial

  28. UB-221

    United Therapeutics Europe Ltd

    Chronic Idiopathic Urticaria

    phase 1 small molecule active

    1 trial

  29. UB-312

    BRIGHT MINDS BIOSCIENCES INC.

    Parkinson's Disease

    phase 1 mab completed

    1 trial

  30. UB-421 SC

    United Therapeutics Europe Ltd

    HIV-1-infection

    phase 1 mab active

    1 trial

  31. UB-421 SC(dB4C7C22-6 mAb)

    United Therapeutics Europe Ltd

    HIV-1 Infection

    phase 1 mab completed

    1 trial

  32. UB-621

    United Therapeutics Europe Ltd

    Herpes Simplex Virus Infection

    phase 1 small molecule completed

    1 trial

  33. UB-921

    United Therapeutics Europe Ltd

    Breast Neoplasm

    phase 1 mab completed

    1 trial

  34. UB-VV410

    The First People's Hospital of Lianyungang

    Systemic Lupus Erythematosus

    phase 1 small molecule active

    1 trial

  35. UCBMC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stroke

    phase 1 mab active

    1 trial

  36. UCMSC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Bronchopleural Fistula

    phase 1 mab active

    1 trial

  37. UECHUP-ALM/23-6

    Lacuna Pharma Pty Ltd

    Antimigraine

    phase 1 other active

    1 trial

  38. UECHUP-ATO/24-3

    Laboratorios Tillomed Spain S.L.U

    Hypercholesterolaemia, Prevention of cardiovascular disease

    phase 1 other active

    1 trial

  39. UECHUP-DAP/24-4

    Laboratorios Tillomed Spain S.L.U

    Diabetes

    phase 1 other active

    1 trial

  40. UECHUP-DON/23-5

    Laboratorios Tillomed Spain S.L.U

    Alzheimer's disease

    phase 1 other active

    1 trial

  41. UECHUP-EDO/25-2

    Laboratorios Tillomed Spain S.L.U

    Healthy volunteers

    phase 1 other active

    1 trial

  42. UECHUP-ESC/25-3

    Laboratorios Tillomed Spain S.L.U

    Antidepressants

    phase 1 other active

    1 trial

  43. UECHUP-LIN-MET/24-1

    Laboratorios Tillomed Spain S.L.U

    diabetes

    phase 1 other active

    1 trial

  44. UECHUP-MEM/25-6

    Laboratorios Tillomed Spain S.L.U

    Alzheimer’s disease

    phase 1 other active

    1 trial

  45. UECHUP-RAS/24-2

    Laboratorios Tillomed Spain S.L.U

    Parkinson´s disease

    phase 1 other active

    1 trial

  46. UECHUP-VOR/24-5

    Laboratorios Tillomed Spain S.L.U

    Antidepressant

    phase 1 other active

    1 trial

  47. UHKT-CAR19-01

    The George Institute

    Relapsed/refractory CD19+ Acute Lymphoblastic Leukaemia and Non-Hodgkin Lymphoma

    phase 1 other active

    1 trial

  48. UI009

    United Therapeutics Europe Ltd

    Health

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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