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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 86 of 99

  1. Tecartus 0.4 - 2 x 10e8 cells dispersion for infusion

    Lacuna Pharma Pty Ltd

    Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r ALL) Relapsed/Refractory B-cell non-Hodgkin lymphoma (r/r NHL)

    phase 1 small molecule active

    1 trial

  2. Teduglutide

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  3. Teduglutide

    Takeda

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  4. Telaprevir

    Vertex Pharmaceuticals (Australia) Pty.

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  5. Telaprevir; Moxifloxacin; Placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 1 small molecule completed

    1 trial

  6. Telavancin

    Theravance Biopharma Ireland Umited

    Healthy

    phase 1 small molecule completed

    1 trial

  7. Telotristat Ethyl

    LEXICON PHARMACEUTICALS, INC.

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  8. Telotristat etiprate

    LEXICON PHARMACEUTICALS, INC.

    Drug Interactions

    phase 1 small molecule completed

    2 trials

  9. Telotristat etiprate

    LEXICON PHARMACEUTICALS, INC.

    QT Interval

    phase 1 small molecule completed

    1 trial

  10. Telotristat etiprate

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  11. Tepotinib

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  12. Terbinafine HCl 250mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  13. Test Montelukast

    GlaxoSmithKline

    Respiratory Disorders

    phase 1 small molecule completed

    1 trial

  14. Test: Favipiravir 200 mg (LOQULAR)

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  15. Tetrahydrobiopterin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation-Induced Dermatitis

    phase 1 small molecule active

    1 trial

  16. Tetrahydrobiopterin 10 mg/kg

    BioMarin Pharmaceutical Australia Pty Ltd

    Claudication, Intermittent

    phase 1 small molecule active

    1 trial

  17. The 10mg dose group

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  18. The Chimeric Antigen Receptor T Cell Immunotherapy (CAR-T)

    Sinobioway Cell Therapy Co.,

    Lymphoma

    phase 1 mab active

    1 trial

  19. The Role of the Amylin Analogue Cagrilintide in Bone Metabolism

    NovoThirteen

    Female (aged between 50-70 years (both included)) with obesity (BMI ≥ 30.0 kg/m2) of post-menopausal state at screening (defined as minimum 12 months of amenorrhea and high levels of follicular stimulating hormone (FSH) ≥16 UI/L. In cases of uncertainty, confirmation of postmenopausal status requires low levels of anti-Müllerian hormone (AMH) and inhibin B).

    phase 1 other active

    1 trial

  20. The TILS001 trial

    The George Institute

    advanced or metastasic triple-negative breast cancer

    phase 1 other active

    1 trial

  21. The bioavailability study of Dapagliflozin

    Laboratorios Tillomed Spain S.L.U

    not applicable (submitted trial is a bioequivalence study

    phase 1 other active

    1 trial

  22. The clinical trial to study a new drug, AP-2.

    Lacuna Pharma Pty Ltd

    ALS and related disorders like frontotemporal dementia and Alexander disease.

    phase 1 other active

    1 trial

  23. Therapeutic Workplace Intervention

    BRIGHT MINDS BIOSCIENCES INC.

    Drug Addiction

    phase 1 other completed

    1 trial

  24. ThisCART19A

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 mab active

    1 trial

  25. ThisCART19A

    The First People's Hospital of Lianyungang

    Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

    phase 1 small molecule active

    1 trial

  26. ThisCART19A with Dose Level 1

    The First People's Hospital of Lianyungang

    CAR

    phase 1 small molecule active

    1 trial

  27. ThisCART22 cells injection

    The First People's Hospital of Lianyungang

    B Cell Malignancy

    phase 1 mab active

    1 trial

  28. ThisCART7 cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    T-Acute Lymphoblastic Leukemia

    phase 1 mab active

    1 trial

  29. TioSMI

    Laboratorios Tillomed Spain S.L.U

    Chronic obstructive pulmonary disease

    phase 1 other active

    1 trial

  30. Tiotropium

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  31. Tipifarnib

    Kura Oncology

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  32. Tipifarnib

    Kura Oncology

    NSCLC

    phase 1 small molecule terminated

    1 trial

  33. Tirzepatide

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  34. Tissue Plasminogen Activator (tPA)

    Hospital Authority, Hong Kong

    Peritoneal Dialysis

    phase 1 small molecule terminated

    1 trial

  35. To evaluate the pharmacokinetics and safety of nolasiban

    Novo Nordisk A/S

    not applicable (submitted trial is a pharmacokinetic study in healthy subjects)

    phase 1 other active

    1 trial

  36. Tofacitinib tablets

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Amyotrophic Lateral Sclerosis

    phase 1 small molecule active

    1 trial

  37. Tolvaptan 15mg or 30mg or 60mg or Placebo

    Otsuka Beijing Research Institute

    Healthy

    phase 1 small molecule completed

    1 trial

  38. Topiramate 2 x 25 mg tablet

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  39. Topiramate 25 mg Capsules

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  40. Topiramate Capsules, 25 mg

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  41. Topiramate IR

    SUPERNUS PHARMACEUTICALS, INC.

    Epilepsy

    phase 1 small molecule completed

    1 trial

  42. Topiramate Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  43. Training with 4D Motion Capture Device

    4D Molecular Therapeutics

    Stroke

    phase 1 other completed

    1 trial

  44. Trandolapril 4 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  45. Tranexamic Acid；

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Iatrogenic Endobronchial Bleeding

    phase 1 small molecule active

    1 trial

  46. Tranilast

    The First People's Hospital of Lianyungang

    Mucinoses

    phase 1 small molecule active

    1 trial

  47. TransCon PEG treprostinil

    United Therapeutics Europe Ltd

    PAH

    phase 1 small molecule terminated

    1 trial

  48. Transdermal Nicotine Patch

    BRIGHT MINDS BIOSCIENCES INC.

    E-cigarette Use

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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