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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 85 of 99

  1. TSC-204-A0201

    TScan Therapeutics

    Head and Neck Cancer

    phase 1 mab active

    1 trial

  2. TTI-101

    Tvardi Therapeutics

    Breast Cancer

    phase 1 small molecule completed

    2 trials

  3. TTI-101

    Tvardi Therapeutics

    Pancreatic Cancer

    phase 1 small molecule active

    1 trial

  4. TTP4000

    vTv Therapeutics

    Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  5. TTP607

    vTv Therapeutics

    Advanced Cancers

    phase 1 small molecule terminated

    1 trial

  6. TTX-MC138-NODAGA-Cu64

    Transcode Therapeutics

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  7. TV-45070

    Teva Pharma GmbH

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  8. TV-46046

    Teva Pharma GmbH

    Contraception

    phase 1 small molecule completed

    2 trials

  9. TV-46046 - 400 mg/mL

    Teva Pharma GmbH

    Pregnancy

    phase 1 small molecule completed

    1 trial

  10. TV44749-BA-10196

    Lacuna Pharma Pty Ltd

    Schizophrenia

    phase 1 other active

    1 trial

  11. TV46017

    Teva Pharma GmbH

    Chronic Obstructive Pulmonary Disease (COPD

    phase 1 small molecule terminated

    1 trial

  12. TV48108

    Teva Pharma GmbH

    Chronic Obstructive Pulmonary Disease

    phase 1 small molecule terminated

    1 trial

  13. TV56192-PD-10191

    Lacuna Pharma Pty Ltd

    Pruritus

    phase 1 other active

    1 trial

  14. TV56286-MB-10193

    Lacuna Pharma Pty Ltd

    Healthy participant

    phase 1 other active

    1 trial

  15. TVB-2640

    Sagimet Biosciences

    Prostatic Neoplasms, Castration-Resistant

    phase 1 small molecule active

    1 trial

  16. TVB-2640

    Sagimet Biosciences

    Solid Malignant Tumor

    phase 1 small molecule completed

    1 trial

  17. TVB-2640 - 50 mg

    Sagimet Biosciences

    Non-alcoholic Steatohepatitis

    phase 1 small molecule completed

    1 trial

  18. TVB-3567

    Sagimet Biosciences

    Acne

    phase 1 small molecule active

    1 trial

  19. TYR200-101

    Tyra Biosciences

    Locally Advanced Cholangiocarcinoma

    phase 1 small molecule active

    1 trial

  20. TYRA-300-B01

    Tyra Biosciences

    Healthy

    phase 1 small molecule active

    1 trial

  21. TYRA-430

    Tyra Biosciences

    Metastatic Hepatocellular Carcinoma

    phase 1 small molecule active

    1 trial

  22. Ta-NPs (2% Tumor Volume)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Locally Recurrent Retroperitoneal Soft Tissue Sarcoma

    phase 1 mab active

    1 trial

  23. Tabalumab

    Eli Lilly and Company

    Multiple Myeloma

    phase 1 mab completed

    1 trial

  24. Tacrolimus

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  25. Tacrolimus

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  26. Takeda's Tetravalent Dengue Vaccine Candidate (TDV)

    Takeda

    Healthy

    phase 1 mab completed

    1 trial

  27. Talabostat Mesylate

    BioXcel Therapeutics

    Cancer of Pancreas

    phase 1 small molecule terminated

    1 trial

  28. Talampanel

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  29. Talampanel (non-radiolabeled), [14C] Talampanel

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule terminated

    1 trial

  30. Talazoparib

    BioMarin Pharmaceutical Australia Pty Ltd

    Childhood Solid Tumors

    phase 1 small molecule completed

    1 trial

  31. Tamsulosin

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  32. Tamsulosin formulation-A

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 small molecule completed

    1 trial

  33. Target CD7 CAR-T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    T-cell Acute Lymphoblastic Leukemia

    phase 1 mab terminated

    1 trial

  34. Targeted CEA CAR-T

    Chongqing Precision Biotech Co., Ltd

    Advanced Lung Cancer

    phase 1 mab active

    4 trials

  35. Tarlatamab

    Amgen

    Neuroendocrine Prostate Cancer

    phase 1 small molecule completed

    1 trial

  36. Tarlatamab

    BEONE MEDICINES AUS PTY LTD

    Extensive Stage Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  37. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy Volunteers

    phase 1 small molecule completed

    4 trials

  38. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  39. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    REM Behavior Disorder

    phase 1 small molecule terminated

    1 trial

  40. Tasimelteon Oral Capsule

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy

    phase 1 small molecule completed

    1 trial

  41. Tasocitinib 10 mg oral tablet

    Pfizer

    Healthy

    phase 1 small molecule completed

    1 trial

  42. Tcrx T cell

    TScan Therapeutics

    Gastric Cancer

    phase 1 mab active

    1 trial

  43. Tebipenem Pivoxil Hydrobromide

    Spero Therapeutics

    Diabetes

    phase 1 small molecule completed

    1 trial

  44. Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) + Placebo

    Spero Therapeutics

    TQT Study

    phase 1 small molecule completed

    1 trial

  45. Tebipenem pivoxil hydrobromide (TBPM-PI-HBr)

    Spero Therapeutics

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  46. Tebipenem pivoxil hydrobromide (TBPM-PI-HBr)

    Spero Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  47. Tebipenem pivoxil hydrobromide (TBPM-PI-HBr) - Reference

    Spero Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  48. Tebipenem tablet form

    Spero Therapeutics

    Relative Bioavailability

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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