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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 84 of 99

  1. TGI-5

    TG THERAPEUTICS, INC.

    CRC (Colorectal Cancer)

    phase 1 small molecule active

    1 trial

  2. TGI-6 Injection

    TG THERAPEUTICS, INC.

    Advanced or Metastatic Solid Tumors

    phase 1 small molecule active

    1 trial

  3. TGR-1202

    TG THERAPEUTICS, INC.

    Non-Hodgkin's Lymphoma

    phase 1 small molecule completed

    1 trial

  4. TGR-1202

    TG THERAPEUTICS, INC.

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

    phase 1 small molecule completed

    1 trial

  5. TGR-1202

    TG THERAPEUTICS, INC.

    Pancreatic Cancer

    phase 1 small molecule completed

    1 trial

  6. TGR-1202 + Obinutuzumab + Chlorambucil

    TG THERAPEUTICS, INC.

    Chronic Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  7. TGR-1202 + brentuximab vedotin

    TG THERAPEUTICS, INC.

    Hodgkin's Lymphoma

    phase 1 small molecule completed

    1 trial

  8. TH-SC01(Umbilical cord mesenchymal stem cells)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rectal Injury

    phase 1 mab active

    1 trial

  9. TH1902

    WINDTREE THERAPEUTICS INC /DE/

    Solid Tumor

    phase 1 small molecule active

    1 trial

  10. THC

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 1 small molecule completed

    1 trial

  11. THC 30mg

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 1 small molecule active

    1 trial

  12. THC High Dose

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 1 small molecule active

    1 trial

  13. TI-0010

    BRIGHT MINDS BIOSCIENCES INC.

    COVID-19

    phase 1 mab active

    1 trial

  14. TIL

    Iovance Biotherapeutics B.V.

    Sarcoma

    phase 1 small molecule completed

    1 trial

  15. TIL in NSCLC

    Disc Medicine

    Respiratory tract diseases

    phase 1 other active

    1 trial

  16. TISA-818-22101

    Lacuna Pharma Pty Ltd

    Idiopathic pulmonary fibrosis

    phase 1 other active

    1 trial

  17. TKM-100201

    Arbutus Biopharma Corp

    Ebola Virus Infection

    phase 1 small molecule terminated

    1 trial

  18. TKM-100802 for Injection

    Arbutus Biopharma Corp

    Ebola Virus Infection

    phase 1 small molecule terminated

    1 trial

  19. TL011

    Teva Pharma GmbH

    DLBCL

    phase 1 mab completed

    1 trial

  20. TMC207

    BRIGHT MINDS BIOSCIENCES INC.

    Tuberculosis

    phase 1 small molecule completed

    1 trial

  21. TMC207TBC1006

    Janssen-Cilag International N.V.

    Tuberculosis

    phase 1 other active

    1 trial

  22. TMS (MagVenture MagPro 100 with MagOption)

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteers

    phase 1 other active

    1 trial

  23. TN-401

    Tenaya Therapeutics

    Arrhythmogenic Right Ventricular Cardiomyopathy

    phase 1 gene therapy active

    1 trial

  24. TNB383B.0001/M22-466

    AbbVie Deutschland GmbH & Co. KG

    Relapsed or refractory multiple myeloma

    phase 1 other active

    1 trial

  25. TNP-2092 capsules

    The First People's Hospital of Lianyungang

    Helicobacter Pylori Infection

    phase 1 small molecule completed

    1 trial

  26. TNX-102 SL

    Tonix Pharmaceuticals Holding

    Healthy Subjects (HS)

    phase 1 small molecule completed

    1 trial

  27. TNX-102 SL

    Tonix Pharmaceuticals Holding

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  28. TNX-102 SL 5.6 mg

    Tonix Pharmaceuticals Holding

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  29. TNX-102 SL Tablet

    Tonix Pharmaceuticals Holding

    Pharmakokinetic

    phase 1 small molecule active

    1 trial

  30. TNX-102 SL Tablets at 2.8 mg

    Tonix Pharmaceuticals Holding

    Healthy Adults

    phase 1 small molecule completed

    1 trial

  31. TNX-1500

    Tonix Pharmaceuticals Holding

    Phase 1 First-in-human Study Involving Healthy Subjects

    phase 1 small molecule completed

    1 trial

  32. TNX-201 35 mg

    Tonix Pharmaceuticals Holding

    Healthy

    phase 1 small molecule completed

    1 trial

  33. TNX-2110

    Tonix Pharmaceuticals Holding

    Detection of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 in Individuals Exposed to SARS-CoV-2

    phase 1 mab terminated

    1 trial

  34. TOP009

    Substipharm

    None - Healthy subjects

    phase 1 other active

    1 trial

  35. TP-03 (Lotilaner Ophthalmic Solution), 0.25%

    Tarsus Pharmaceuticals

    Healthy

    phase 1 small molecule completed

    1 trial

  36. TP-05 (lotilaner oral capsules)

    Tarsus Pharmaceuticals

    Healthy

    phase 1 small molecule completed

    1 trial

  37. TP-05 (lotilaner oral), fasted group

    Tarsus Pharmaceuticals

    Healthy

    phase 1 small molecule completed

    1 trial

  38. TPST-1495 twice daily

    Tempest Therapeutics

    Solid Tumor

    phase 1 small molecule completed

    1 trial

  39. TPT0301-001

    Alphapharm Pty Ltd

    adjunctive neuropathic pain

    phase 1 other active

    1 trial

  40. TQB2101 for Injection

    Nanjing Zenshine Pharmaceuticals

    Advanced Hematologic Malignancies

    phase 1 small molecule active

    1 trial

  41. TQB2825 Injection (Subcutaneous Injection)

    Shanghai University of Traditional Chinese Medicine

    CD20-positive Hematological Malignancies

    phase 1 small molecule active

    1 trial

  42. TQF3250 placebo

    Chia Tai Tianqing Pharmaceutical Group Co.,

    Hyperglycemia

    phase 1 small molecule active

    1 trial

  43. TRAME-13-25

    Lacuna Pharma Pty Ltd

    Adjuvant treatment of BRAF V600E or V600K mutation-positive melanoma (in combination with dabrafenib);, BRAF V600E mutation-positive unresectable or metastatic solid tumors;, BRAF V600E mutation-positive metastatic non-small cell lung cancer (NSCLC), in combination with dabrafenib;, BRAF V600E mutation-positive low-grade glioma (LGG)., BRAF V600E mutation-positive locally advanced or metastatic anaplastic thyroid cancer (ATC);, BRAF V600E or V600K mutation-positive unresectable or metastatic melanoma, as a single agent in BRAF-inhibitor treatment-naïve patients or in combination with dabrafenib;

    phase 1 other active

    1 trial

  44. TRIN2755

    BRIGHT MINDS BIOSCIENCES INC.

    Neoplasms

    phase 1 small molecule active

    1 trial

  45. TRK-100STP (BERASUS LA)

    Astellas Pharma Inc

    Healthy

    phase 1 small molecule completed

    1 trial

  46. TRU-016

    Aptevo Therapeutics

    B-cell Small Lymphocytic Lymphoma Recurrent

    phase 1 small molecule completed

    1 trial

  47. TRU-016 (anti-CD37 protein therapeutic)

    Aptevo Therapeutics

    Chronic Lymphocytic Leukemia (CLL)

    phase 1 small molecule completed

    1 trial

  48. TSB-9-W1

    Biotech Pharmaceutical Co.,

    Metastatic Colorectal Cancer

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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