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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 80 of 99

  1. Standardized Research E-cigarette (SREC)

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking, Cigarette

    phase 1 small molecule active

    1 trial

  2. Stelara

    Rani Therapeutics Holdings

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  3. Stem Cell

    EuroGen Pharmaceuticals Ltd

    Neurological; Disorder, Nervous System

    phase 1 mab terminated

    1 trial

  4. Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2

    Arrowhead Pharmaceuticals Ireland Limited

    spinocerebellar ataxia type 2

    phase 1 other active

    1 trial

  5. Study of BGB-11417 in Patients with Mature B Cell Malignancies

    BEONE MEDICINES AUS PTY LTD

    Mature B Cell Malignancies

    phase 1 other active

    1 trial

  6. Study of GS-0151 in Participants With Rheumatoid Arthritis

    Gilead Sciences Pty Limited

    Rheumatoid Arthritis

    phase 1 other active

    1 trial

  7. Study of GS-5319 in Adults With Solid Tumors

    Gilead Sciences Pty Limited

    Advanced solid tumors

    phase 1 other active

    1 trial

  8. Study of PIT565 in relapsed and/or refractory B-cell malignancies

    Novartis Pharmaceuticals

    Relapsed and/or refractory B-cell Non-Hodgkin lymphoma (R/R B-NHL) and relapsed and/or refractory B-cell acute lymphoblastic leukemia (R/R B-ALL)

    phase 1 other active

    1 trial

  9. Study of U3-1402 in subjects with non-small cell lung cancer

    Daiichi Sankyo

    METASTATIC OR UNRESECTABLE NON-SMALL CELL LUNG CANCER

    phase 1 other active

    1 trial

  10. Subconjunctival aflibercept

    Regeneron UK Limited

    Corneal Neovascularization

    phase 1 small molecule terminated

    1 trial

  11. Subcutaneous Trastuzumab Deruxtecan Phase 1 Trial.

    Daiichi Sankyo

    Advanced Solid Tumor

    phase 1 other active

    1 trial

  12. Sublingual Tizanidine HCl

    Teva Pharma GmbH

    Traumatic Brain Injury

    phase 1 small molecule completed

    1 trial

  13. Sublingual film containing BXCL501 (Dexmedetomidine)

    BioXcel Therapeutics

    Agitation

    phase 1 small molecule completed

    1 trial

  14. Suboxone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-related Disorders

    phase 1 small molecule completed

    1 trial

  15. Sugar Pill

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 1 small molecule completed

    1 trial

  16. Sulfasalazine

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  17. Sulopenem

    Iterum Therapeutics plc

    Urinary Tract Infections

    phase 1 small molecule terminated

    1 trial

  18. Sumatriptan succinate

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    3 trials

  19. Sumatriptan succinate

    Teva Pharma GmbH

    Migraine Disorders

    phase 1 small molecule completed

    1 trial

  20. Sunitinib, Pemetrexed

    Pfizer

    Neoplasm, Malignant

    phase 1 small molecule completed

    1 trial

  21. Sup19 CAR-T

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    B-Acute Lymphoblastic Leukemia

    phase 1 mab active

    1 trial

  22. Sutezolid

    BRIGHT MINDS BIOSCIENCES INC.

    Tuberculosis

    phase 1 small molecule completed

    1 trial

  23. Switch active lifestyles brought to you by MediaWise

    Lxo Ireland Designated Activity Company

    Overweight

    phase 1 other completed

    1 trial

  24. T cell injection targeting CD7 chimeric antigen receptor

    The First People's Hospital of Lianyungang

    CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies

    phase 1 mab active

    1 trial

  25. T cell injection targeting CD7 chimeric antigen receptor

    The First People's Hospital of Lianyungang

    T Lymphoblastic Leukemia/Lymphoma

    phase 1 mab active

    1 trial

  26. T3011

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Malignant Ascites

    phase 1 small molecule active

    1 trial

  27. TAEST16001

    Chongqing Precision Biotech Co., Ltd

    Liver Cancer Stage IV

    phase 1 small molecule completed

    1 trial

  28. TAEST16001 cells

    Chongqing Precision Biotech Co., Ltd

    Soft Tissue Sarcoma

    phase 1 mab active

    1 trial

  29. TAF/EVG Vaginal Insert

    United Therapeutics Europe Ltd

    Hiv

    phase 1 small molecule completed

    1 trial

  30. TAF/EVG vaginal insert

    United Therapeutics Europe Ltd

    Safety Issues

    phase 1 small molecule completed

    1 trial

  31. TAK-004

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  32. TAK-007

    Takeda

    Refractory Lupus Nephritis

    phase 1 mab terminated

    1 trial

  33. TAK-020

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  34. TAK-020 Captisol Oral Solution

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  35. TAK-041

    NEUROCRINE BIOSCIENCES INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  36. TAK-058

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  37. TAK-058

    Takeda

    Schizophrenia

    phase 1 small molecule terminated

    1 trial

  38. TAK-058 (ENV8058)

    Takeda

    Dose Finding Study

    phase 1 small molecule completed

    1 trial

  39. TAK-063

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  40. TAK-063

    Takeda

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  41. TAK-071

    Takeda

    Alzheimer Disease

    phase 1 small molecule terminated

    1 trial

  42. TAK-079

    Takeda

    Autoimmune Disease

    phase 1 small molecule completed

    1 trial

  43. TAK-079

    Takeda

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  44. TAK-079

    Takeda

    Systemic Lupus Erythematosus

    phase 1 small molecule completed

    1 trial

  45. TAK-079-1006

    Takeda

    IgAN is Primary Immunoglobulin A Nephropathy (IgAN) (also known as Berger's disease)

    phase 1 other active

    1 trial

  46. TAK-102

    Takeda

    Solid Tumors

    phase 1 mab terminated

    1 trial

  47. TAK-103

    Takeda

    Solid Tumors

    phase 1 mab terminated

    1 trial

  48. TAK-105-a

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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