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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 79 of 99

  1. Scopolamine

    Takeda

    Healthy Volunteers

    phase 1 small molecule terminated

    1 trial

  2. Segesterone Acetate and Ethinyl Estradiol

    TherapeuticsMD

    Women

    phase 1 small molecule completed

    1 trial

  3. Segesterone Acetate and Ethinyl Estradiol

    TherapeuticsMD

    Contraception

    phase 1 small molecule completed

    1 trial

  4. Selinexor

    Karyopharm Therapeutics Inc

    Colorectal Neoplasm

    phase 1 small molecule terminated

    1 trial

  5. Selinexor

    Karyopharm Therapeutics Inc

    Amyloid

    phase 1 small molecule terminated

    1 trial

  6. Selinexor

    Karyopharm Therapeutics Inc

    Liposarcoma

    phase 1 small molecule terminated

    1 trial

  7. Selinexor

    Karyopharm Therapeutics Inc

    Solid Tumor

    phase 1 small molecule completed

    1 trial

  8. Selinexor

    Karyopharm Therapeutics Inc

    Soft Tissue Sarcoma

    phase 1 small molecule completed

    1 trial

  9. Selinexor

    Karyopharm Therapeutics Inc

    Refractory Multiple Myeloma

    phase 1 small molecule active

    1 trial

  10. Selinexor

    Karyopharm Therapeutics Inc

    Prolymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  11. Selinexor Pill

    Karyopharm Therapeutics Inc

    Hepatocellular Carcinoma

    phase 1 small molecule terminated

    1 trial

  12. Serine（Oral）

    The First People's Hospital of Lianyungang

    Advanced Colorectal Cancer

    phase 1 small molecule active

    1 trial

  13. Setmelanotide

    Rhythm Pharmaceuticals Netherlands B.V.

    Renal Insufficiency

    phase 1 small molecule completed

    1 trial

  14. Shenkang decoction

    The First People's Hospital of Lianyungang

    Chronic Renal Failure

    phase 1 small molecule completed

    1 trial

  15. Shigella sonnei 53G

    United Therapeutics Europe Ltd

    Shigellosis

    phase 1 mab active

    2 trials

  16. Shigella sonnei 53G

    United Therapeutics Europe Ltd

    Healthy

    phase 1 mab completed

    1 trial

  17. Sialic Acid Extended Release (SA-ER) Tablets

    Ultragenyx UK Limited

    Hereditary Inclusion Body Myopathy (HIBM)

    phase 1 small molecule completed

    1 trial

  18. Signature Cord Prime

    Forteo

    Osteoarthritis, Knee

    phase 1 mab active

    1 trial

  19. SilMAKin

    Topiloric/Uriadec

    chronic liver disease

    phase 1 other active

    1 trial

  20. Silodosin

    Hospital Authority, Hong Kong

    Benign Prostatic Hyperplasia

    phase 1 small molecule completed

    1 trial

  21. Simvastatin

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  22. Simvastatin

    United Therapeutics Europe Ltd

    Recurrent Acute Pancreatitis

    phase 1 small molecule active

    1 trial

  23. Simvastatin

    Aurinia Pharmaceuticals

    Drug-drug Interaction

    phase 1 small molecule completed

    1 trial

  24. Simvastatin

    Madrigal Pharmaceuticals EU Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  25. Single Ascending Dose of SAB-176

    SAB Biotherapeutics

    PHA1A

    phase 1 small molecule active

    1 trial

  26. Single FT1050 treated UCB unit

    Zafatek

    Non-Hodgkin's Lymphoma (NHL)

    phase 1 mab completed

    1 trial

  27. Single and multiple ascending dose of ZP9830 in healthy participants

    Zealand Pharma A/S

    Autoimmune diseases

    phase 1 other active

    1 trial

  28. Single dose intravenous injection of BBM 002

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hemophilia A

    phase 1 gene therapy active

    1 trial

  29. Sinovac PCV24 formulation 1

    Sinovac Research and Development Co.,

    Pneumococcal Infectious Disease

    phase 1 mab completed

    2 trials

  30. Small RNA sequencing

    Inhibitor Therapeutics

    Fertility

    phase 1 gene therapy completed

    1 trial

  31. Sobi.BIVV001-003

    Swedish Orphan Biovitrum AB (publ)

    Haemophilia A

    phase 1 other active

    1 trial

  32. Sodium Zirconium Cyclosilicate (ZS)

    AstraZeneca

    Hyperkalemia

    phase 1 small molecule completed

    1 trial

  33. Sodium phenylbutyrate

    ZEVRA THERAPEUTICS, INC.

    Combined D,L-2-hydroxyglutaric Aciduria

    phase 1 small molecule active

    1 trial

  34. Solriamfetol 150 mg Oral Tablet

    Axsome Therapeutics

    Narcolepsy

    phase 1 small molecule completed

    1 trial

  35. Sonelokimab

    MoonLake Immunotherapeutics

    Relative Bioequivalence

    phase 1 small molecule completed

    1 trial

  36. Sonodynamic therapy (SDT)

    The First People's Hospital of Lianyungang

    Carotid Atherosclerosis

    phase 1 other completed

    1 trial

  37. Sonrotoclax

    BEONE MEDICINES AUS PTY LTD

    Mature B-Cell Malignancies

    phase 1 small molecule active

    1 trial

  38. Sotagliflozin

    LEXICON PHARMACEUTICALS, INC.

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  39. Sotagliflozin (SOTA) followed by 3 drugs in a random order

    LEXICON PHARMACEUTICALS, INC.

    Platelet Function and Reactivity Tests

    phase 1 small molecule active

    1 trial

  40. Soticlestat

    Takeda

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  41. Soticlestat

    Takeda

    Healthy Volunteers

    phase 1 small molecule terminated

    4 trials

  42. Soticlestat 300 mg

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  43. Sotrovimab

    Vir Biotechnology

    COVID-19 Infection

    phase 1 mab terminated

    1 trial

  44. Spermine

    Paul Hartmann Pty Ltd

    Premature Birth

    phase 1 mab completed

    1 trial

  45. Spesolimab

    Boehringer Ingelheim

    Psoriasis

    phase 1 small molecule completed

    1 trial

  46. Spinraza 12 mg solution for injection

    Biogen

    Spinal Muscular Atrophy

    phase 1 small molecule active

    1 trial

  47. Spironolactone

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol Use Disorder

    phase 1 small molecule active

    1 trial

  48. Sporozoite Challenge Model for Plasmodium vivax in Humans

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria, Vivax

    phase 1 mab completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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