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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 74 of 99

  1. Radiation: 18F-AlF-FAPi-04

    Sichuan Provincial People's Hospital

    Tumor, Solid

    phase 1 small molecule active

    1 trial

  2. Radiolabeled Prucalopride Succinate

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  3. Radiolabeled SPD557

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  4. Radiolabeled SPD602 (FBS0701, SSP-004184)

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  5. Radiolabelled Diclofenac Tablet A

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule completed

    1 trial

  6. Radiolabelled T4 Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule completed

    1 trial

  7. Ramelteon 8 mg

    Takeda

    Insomnia

    phase 1 small molecule completed

    1 trial

  8. Ramipril 10 mg capsule

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    3 trials

  9. Ramipril tablet 10 mg

    LIGAND PHARMACEUTICALS INC

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  10. Ramipril/Hydrochlorothiazide tablet 10 mg/25 mg

    LIGAND PHARMACEUTICALS INC

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  11. Randomized for not applicable (submitted trial is bioavailability)

    Lacuna Pharma Pty Ltd

    not applicable (submitted trial is bioavailability)

    phase 1 other active

    1 trial

  12. Randomized for not applicable (submitted trial…

    Lacuna Pharma Pty Ltd

    not applicable (submitted trial is a bioequivalence in healthy subjects)

    phase 1 other active

    1 trial

  13. RaniPill capsule containing octreotide

    Rani Therapeutics Holdings

    Healthy Volunteers

    phase 1 other completed

    1 trial

  14. Ranolazine

    BRIGHT MINDS BIOSCIENCES INC.

    Drug-induced QT Prolongation

    phase 1 small molecule completed

    1 trial

  15. Rapamycin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Graves Ophthalmopathy

    phase 1 small molecule active

    1 trial

  16. Recombinant ADAMTS13

    Takeda

    Hereditary Thrombotic Thrombocytopenic Purpura (TTP)

    phase 1 small molecule completed

    1 trial

  17. Recombinant Humanized Anti-IL-36R Monoclonal antibody and Placebo

    Shanghai University of Traditional Chinese Medicine

    Healthy

    phase 1 small molecule completed

    1 trial

  18. Recombinant NV-A01 adenovirus injection

    The First People's Hospital of Lianyungang

    Advanced Glioblastoma Patients

    phase 1 small molecule active

    1 trial

  19. Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    COVID-19

    phase 1 mab completed

    1 trial

  20. Recombinant SARS-CoV-2 Fusion Protein Vaccine

    Livzon Pharmaceutical Group

    COVID19

    phase 1 mab completed

    1 trial

  21. Recombinant adeno-associated virus administration

    Kunming Hope of Health Hospital

    Menkes Syndrome

    phase 1 small molecule terminated

    1 trial

  22. Recombinant erythropoietin stimulating protein

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Chronic Renal Failure

    phase 1 small molecule active

    1 trial

  23. Recombinant human C1 esterase inhibitor

    Takeda

    Hereditary Angioedema (HAE)

    phase 1 small molecule completed

    1 trial

  24. Recombinant human arginase 1 Peg5000

    International Peace Maternity and Child Health Hospital

    Leukemia

    phase 1 small molecule terminated

    1 trial

  25. Recombinant human hyaluronidase PH20 (rHuPH20)

    HALOZYME THERAPEUTICS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  26. Recombinant human thrombopoietin

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Liver Cirrhosis

    phase 1 small molecule active

    1 trial

  27. Recombinant human tissue kallikrein

    DiaMedica Therapeutics

    Stroke

    phase 1 small molecule completed

    1 trial

  28. Recombinant oncolytic herpes simplex virus type Ⅰ (R130)

    Shanghai University of Traditional Chinese Medicine

    Osteosarcoma

    phase 1 small molecule active

    1 trial

  29. Recombinant von Willebrand factor : recombinant FVIII (rVWF:rFVIII)

    Takeda

    Von Willebrand Disease

    phase 1 mab completed

    1 trial

  30. Refametinib (BAY86-9766)

    Bayer HealthCare AG

    Neoplasms

    phase 1 small molecule completed

    1 trial

  31. Rehabilitation

    United Therapeutics Europe Ltd

    Stroke

    phase 1 other completed

    1 trial

  32. Relacorilant

    CORCEPT THERAPEUTICS INC

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  33. Relacorilant

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  34. Relacorilant

    CORCEPT THERAPEUTICS INC

    Adrenocortical Carcinoma

    phase 1 small molecule completed

    1 trial

  35. Relacorilant (3x100 mg softgel capsules)

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  36. Relacorilant 350mg

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  37. Relacorilant Fasted

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  38. Relacorilant under fasted conditions

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  39. Repetitive Transcranial Magnetic Stimulation

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 1 other terminated

    1 trial

  40. Replens and coconut oil

    Summit Therapeutics

    Genitourinary Abnormality

    phase 1 other terminated

    1 trial

  41. Research ENDS S-TA-U001

    BRIGHT MINDS BIOSCIENCES INC.

    Cigarette Smoking

    phase 1 small molecule completed

    1 trial

  42. Reserpine

    BRIGHT MINDS BIOSCIENCES INC.

    Amphetamine-Related Disorders

    phase 1 small molecule active

    1 trial

  43. Reslizumab IV

    Teva Pharma GmbH

    Absolute Bioavailability

    phase 1 small molecule completed

    1 trial

  44. Retifanlimab

    ACTUATE THERAPEUTICS, INC.

    Pancreatic Adenocarcinoma

    phase 1 small molecule active

    1 trial

  45. Revumenib

    Syndax Pharmaceuticals

    Relapsed/Refractory Leukemias

    phase 1 small molecule completed

    1 trial

  46. Revumenib

    Syndax Pharmaceuticals

    Acute Leukemia

    phase 1 small molecule completed

    1 trial

  47. Revumenib

    Syndax Pharmaceuticals

    Blinatumomab

    phase 1 small molecule active

    1 trial

  48. Revumenib

    Syndax Pharmaceuticals

    Refractory Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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