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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 69 of 99

  1. Phase 1 Safety and Tolerability Study of ALN-F1202 in Healthy Adults.

    Lacuna Pharma Pty Ltd

    Healthy Volunteer

    phase 1 other active

    1 trial

  2. Phase 1 Safety and Tolerability Study of REGN9533 in Healthy Adults.

    Lacuna Pharma Pty Ltd

    Healthy Volunteers

    phase 1 other active

    1 trial

  3. Phase 1 Single Ascending Doses (SAD) of M5542 in Healthy Participants

    Merck Sharp and Dohme

    Healthy

    phase 1 other active

    1 trial

  4. Phase 1 Study of IMC-P115C in Advanced PRAME Positive Cancers

    Immunocore Ireland Limited

    Advanced PRAME Positive Cancers

    phase 1 other active

    1 trial

  5. Phase 1 Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancer

    Janssen-Cilag International N.V.

    Metastatic colorectal cancer and Gastric cancer

    phase 1 other active

    1 trial

  6. Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

    Olema Pharmaceuticals

    Advanced or Metastatic Solid Tumors

    phase 1 other active

    1 trial

  7. Phase 1 Study of PYX-106 in Solid Tumors

    Pyxis Oncology

    Solid Tumors

    phase 1 other active

    1 trial

  8. Phase 1 Study of PYX-201 in Solid Tumors

    Pyxis Oncology

    Advanced solid tumors

    phase 1 other active

    1 trial

  9. Phase 1 study on SAR443122 bioavailability and food effect in healthy adults

    Sanofi-aventis Healthcare Pty Ltd

    Colitis ulcerative

    phase 1 other active

    1 trial

  10. Phase 1 trial of valemetostat and darolutamide in mCRPC

    Daiichi Sankyo

    Metastatic Castration Resistant Prostate Cancer (mCRPC)

    phase 1 other active

    1 trial

  11. Phase 1: Web-based intervention (MyWebQuit) with 1-way text messages

    BRIGHT MINDS BIOSCIENCES INC.

    Social Anxiety Disorder

    phase 1 other terminated

    1 trial

  12. Phase 1b Study of Tarlatamab + ZL-1310 +/- Anti-PD-L1 in Small Cell Lung Cancer

    Amgen

    Small Cell Lung Cancer

    phase 1 other active

    1 trial

  13. Phase I Study of PM54 Administered to Patients with Advanced Solid Tumors

    Lacuna Pharma Pty Ltd

    Selected Advanced Solid Tumors

    phase 1 other active

    1 trial

  14. Phase I study of 225Ac-PSMA I&T in prostate cancer

    Disc Medicine

    metastatic prostate cancer

    phase 1 other active

    1 trial

  15. Phase I study of MGY825 in patients with lung cancer

    Novartis Pharmaceuticals

    Advanced non-small cell lung cancer with or without NFE2L2/KEAP1/CUL3 mutations in adult patients

    phase 1 other active

    1 trial

  16. Phase I-Ib clinical trial of safety and immun... for graft-versus-host disease

    The George Institute

    graft-versus-host disease

    phase 1 other active

    1 trial

  17. Phase I-Ib clinical trial of safety and immun... for graft-versus-host disease

    The George Institute

    graft-versus-host disease

    phase 1 other active

    1 trial

  18. Phenytoin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule completed

    1 trial

  19. Physical Activity Educational Materials

    United Therapeutics Europe Ltd

    Physical Inactivity

    phase 1 other completed

    1 trial

  20. Pimavanserin

    Acadia Pharmaceuticals B.V.

    Parkinson Disease

    phase 1 small molecule terminated

    1 trial

  21. Pioglitazone

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  22. Piracetam

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule terminated

    2 trials

  23. Pirfenidone

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  24. Pitavastatin

    United Therapeutics Europe Ltd

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  25. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Abuse

    phase 1 small molecule completed

    1 trial

  26. Placebo

    Rhythm Pharmaceuticals Netherlands B.V.

    Obesity

    phase 1 small molecule completed

    1 trial

  27. Placebo

    Regeneron UK Limited

    Atopic Dermatitis

    phase 1 small molecule completed

    3 trials

  28. Placebo

    Mirum Pharmaceuticals International B.V.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  29. Placebo

    Takeda

    Virus, Zika

    phase 1 small molecule completed

    1 trial

  30. Placebo

    Sarepta Therapeutics

    Ebola Hemorrhagic Fever

    phase 1 small molecule completed

    1 trial

  31. Placebo

    Nektar Therapeutics UK Limited

    Psoriasis

    phase 1 small molecule completed

    1 trial

  32. Placebo

    Eloxx Pharmaceuticals

    Genetic Disease

    phase 1 small molecule completed

    1 trial

  33. Placebo

    Madrigal Pharmaceuticals EU Limited

    Drug Safety

    phase 1 small molecule completed

    2 trials

  34. Placebo

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  35. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    THC

    phase 1 small molecule completed

    1 trial

  36. Placebo

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 1 small molecule completed

    1 trial

  37. Placebo

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  38. Placebo

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy

    phase 1 small molecule completed

    1 trial

  39. Placebo

    KYOWA KIRIN AUSTRALIA PTY LTD

    Healthy Volunteers Essential Hypertension

    phase 1 small molecule active

    1 trial

  40. Placebo

    Pfizer

    Respiratory Syncytial Virus Infections

    phase 1 small molecule terminated

    1 trial

  41. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 1 small molecule active

    1 trial

  42. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Addiction

    phase 1 small molecule completed

    1 trial

  43. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  44. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    D-limonene and THC Pharmacodynamics

    phase 1 small molecule completed

    1 trial

  45. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule active

    1 trial

  46. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    2 trials

  47. Placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Memory

    phase 1 small molecule completed

    1 trial

  48. Placebo

    The First People's Hospital of Lianyungang

    Asthma

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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