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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 68 of 99

  1. PVSRIPO

    United Therapeutics Europe Ltd

    Invasive Breast Cancer

    phase 1 mab completed

    1 trial

  2. PYX-106

    Pyxis Oncology

    Solid Tumor

    phase 1 small molecule active

    1 trial

  3. PYX-201

    Pyxis Oncology

    Solid Tumor

    phase 1 small molecule active

    1 trial

  4. Pacing Lead

    Rhythm Pharmaceuticals Netherlands B.V.

    Heart Failure

    phase 1 other completed

    1 trial

  5. Paclitaxel

    Hospital Authority, Hong Kong

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  6. Paclitaxel

    Jazz Pharmaceuticals Ireland Limited

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  7. Palazestrant

    Olema Pharmaceuticals

    Metastatic Breast Cancer

    phase 1 small molecule active

    1 trial

  8. Palbociclib + Taselisib / Pictilisib

    United Therapeutics Europe Ltd

    Advanced Solid Tumours

    phase 1 small molecule completed

    1 trial

  9. Panama ID: 8070

    Disc Medicine

    peritoneal metastases of colorectal origin

    phase 1 other active

    1 trial

  10. Pantoprazole Sodium 40 mg delayed-release tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  11. Parotid Gland

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 other completed

    1 trial

  12. Paroxetine HCl

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  13. Part 1

    Harmony Biosciences Holdings

    Drug Interaction

    phase 1 small molecule completed

    1 trial

  14. Part 1 TPST-1120

    Tempest Therapeutics

    Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  15. Part 1: Cream

    BRIGHT MINDS BIOSCIENCES INC.

    Systemic Exposure to Sunscreen Ingredients

    phase 1 small molecule completed

    1 trial

  16. Part A: Dose Escalation of Cantrixil

    KAZIA THERAPEUTICS LTD

    Ovarian Neoplasms

    phase 1 small molecule completed

    1 trial

  17. Pazopanib

    GlaxoSmithKline

    Neoplasms, Colorectal

    phase 1 small molecule completed

    1 trial

  18. PegInterferon

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 1 small molecule completed

    1 trial

  19. Pegfilgrastim

    Biotech Pharmaceutical Co.,

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  20. Peginterferon lambda

    Biotech Pharmaceutical Co.,

    Hepatitis C

    phase 1 mab completed

    1 trial

  21. Pegylated Recombinant Candida Utilis Uricase for Injection

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Gout

    phase 1 small molecule active

    1 trial

  22. Pelareorep

    ONCOLYTICS BIOTECH INC

    Breast Cancer

    phase 1 mab terminated

    1 trial

  23. Peldesine

    Biocryst

    HIV Infections

    phase 1 small molecule completed

    1 trial

  24. Pembrolizumab

    Takeda

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule completed

    1 trial

  25. Pembrolizumab

    United Therapeutics Europe Ltd

    Thoracic Tumours

    phase 1 small molecule completed

    1 trial

  26. Pembrolizumab

    Cardiff Oncology

    Anal Cancer Stage III A

    phase 1 small molecule active

    1 trial

  27. Pembrolizumab

    United Therapeutics Europe Ltd

    Cervix Cancer

    phase 1 other terminated

    1 trial

  28. Pemetrexed

    The First People's Hospital of Lianyungang

    Leptomeningeal Metastases

    phase 1 small molecule completed

    1 trial

  29. Peptides (N,R&C) formulated in Montanide ISA 720

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria, Vivax

    phase 1 small molecule completed

    1 trial

  30. Perindopril

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 1 small molecule completed

    1 trial

  31. Period 1: AT-527 550 mg

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  32. Petadeferitrin-BA-01

    Lacuna Pharma Pty Ltd

    Iron overload from thalassemia, transfusion-dependent myelodysplastic syndromea and haemolysis

    phase 1 other active

    1 trial

  33. Pevifoscorvir Sodium (ALG-000184)

    Aligos Therapeutics

    Chronic Hepatitis B Infection

    phase 1 small molecule active

    1 trial

  34. Pevifoscorvir Sodium (ALG-000184)

    Aligos Therapeutics

    Chronic Hepaititis B Infections

    phase 1 small molecule active

    1 trial

  35. Pevonedistat

    Takeda

    Acute Myelogenous Leukemia

    phase 1 small molecule completed

    1 trial

  36. Pevonedistat

    Takeda

    Advanced Solid Neoplasm

    phase 1 small molecule completed

    2 trials

  37. Pevonedistat

    Takeda

    Refractory Acute Lymphoblastic Leukemia

    phase 1 small molecule completed

    1 trial

  38. Pevonedistat

    Takeda

    Myelofibroses

    phase 1 small molecule terminated

    1 trial

  39. Pevonedistat

    Takeda

    Advanced Solid Tumors, Neoplasms, Advanced Solid

    phase 1 small molecule completed

    1 trial

  40. Pevonedistat 25 mg/m^2

    Takeda

    Leukemia, Myeloid, Acute

    phase 1 small molecule completed

    1 trial

  41. Pf-04937319

    Pfizer

    Healthy

    phase 1 small molecule completed

    1 trial

  42. Ph 1 Study of ORIC-944 in Patients with Metastatic Prostate Cancer.

    Topiloric/Uriadec

    Prostate cancer

    phase 1 other active

    1 trial

  43. Pharmaceutical-lipid aspirin (PL-ASA)

    Protalix BioTherapeutics

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  44. Pharmacogenomics testing for clopidogrel responsiveness

    BRIGHT MINDS BIOSCIENCES INC.

    Stroke

    phase 1 other completed

    1 trial

  45. Pharmacokinetic study of colistimethate sodium

    Zaklady FarmaFarmaceutyczne Polpharma S.Aceutyczne Polpharma S.A.

    serious infections caused by selected aerobic gram-negative pathogens in patients with limited treatment options

    phase 1 other active

    1 trial

  46. Pharmacy-based methadone administration and dispensing

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-use Disorder

    phase 1 small molecule completed

    1 trial

  47. Phase 0 trial of CBD in recurrent glioblastoma patients

    Disc Medicine

    Glioblastoma

    phase 1 other active

    1 trial

  48. Phase 1 First-in-Human Study of JNJ-95566692 in Participants with NHLs

    Janssen-Cilag International N.V.

    Non-Hodgkin Lymphoid Malignancies (NHLs)

    phase 1 other active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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