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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 67 of 99

  1. PLX-PAD

    United Therapeutics Europe Ltd

    Pulmonary Arterial Hypertension

    phase 1 small molecule terminated

    1 trial

  2. PM14-A-003-20

    Lacuna Pharma Pty Ltd

    Advanced solid tumors

    phase 1 other active

    1 trial

  3. PMV via Puffhaler® device

    Serum Life Science Europe GmbH

    Prophylaxis for the Measles Infection

    phase 1 mab completed

    1 trial

  4. PN-232

    Protagonist Therapeutics, Inc

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  5. PN-235

    Protagonist Therapeutics, Inc

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  6. PN-881 Oral Solution

    Protagonist Therapeutics, Inc

    Healthy Volunteer

    phase 1 small molecule active

    1 trial

  7. PNEUMOSTEM®

    Samsung Bioepis NL B.V.

    Pulmonary Arterial Hypertension (PAH)

    phase 1 mab active

    1 trial

  8. PNT001

    United Therapeutics Europe Ltd

    Traumatic Brain Injury

    phase 1 mab terminated

    1 trial

  9. PONAT-14-25

    Lacuna Pharma Pty Ltd

    chronic myeloid leukemia, Philadelphia chromosome-positive acute lymphoblastic leukemia

    phase 1 other active

    1 trial

  10. PQ-0810-001

    ProQR Therapeutics N.V.

    Cholestatic liver disease

    phase 1 other active

    1 trial

  11. PRA

    CNS Pharmaceuticals

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  12. PRAX-628

    Chongqing Precision Biotech Co., Ltd

    Healthy

    phase 1 small molecule active

    1 trial

  13. PRAX-628-102

    Chongqing Precision Biotech Co., Ltd

    Epilepsy

    phase 1 other active

    1 trial

  14. PRG-1801

    Hospital Authority, Hong Kong

    Immune Thrombocytopenia

    phase 1 small molecule active

    1 trial

  15. PRG2302

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia

    phase 1 small molecule active

    1 trial

  16. PRIMROSE D9970C00001

    AstraZeneca AB

    Advanced/metastatic solid tumors that are MTAP deficient.

    phase 1 small molecule active

    1 trial

  17. PRO 2000/5 Gel (P)

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 1 small molecule completed

    1 trial

  18. PRO-040201

    Arbutus Biopharma Corp

    Hypercholesterolemia

    phase 1 small molecule terminated

    1 trial

  19. PRO-PanFlu-1001

    Sinovac Research and Development Co.,

    Influenza

    phase 1 mab completed

    1 trial

  20. PROT-CL-NP101-015.01

    Teva Pharma GmbH

    Acute Migraine

    phase 1 small molecule completed

    1 trial

  21. PRT12396

    Prelude Therapeutics Inc

    Polycythemia Vera (PV)

    phase 1 small molecule active

    1 trial

  22. PRT1419

    Prelude Therapeutics Inc

    Acute Myeloid Leukemia

    phase 1 small molecule terminated

    1 trial

  23. PRT1419

    Prelude Therapeutics Inc

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  24. PRT1419

    Prelude Therapeutics Inc

    Sarcoma

    phase 1 small molecule completed

    1 trial

  25. PRT2527

    Prelude Therapeutics Inc

    Sarcoma

    phase 1 small molecule completed

    1 trial

  26. PRT2527

    Prelude Therapeutics Inc

    Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)

    phase 1 small molecule completed

    1 trial

  27. PRT3645

    Prelude Therapeutics Inc

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  28. PRT543

    Prelude Therapeutics Inc

    Relapsed/Refractory Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  29. PRT7732

    Prelude Therapeutics Inc

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  30. PRT7732-01

    Prelude Therapeutics Inc

    esophageal, gastric, or gastroesophageal junction adenocarcinoma, esophageal, gastric, or gastroesophageal junction squamous cell carcinoma, Non-small cell lung cancer (NSCLC), Advanced or Metastatic Solid Tumors with a SMARCA4 Mutation

    phase 1 other active

    1 trial

  31. PRT811

    Prelude Therapeutics Inc

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  32. PRV-002

    Odyssey Therapeutics

    Traumatic Brain Injury (TBI)

    phase 1 small molecule completed

    1 trial

  33. PRX-105

    Protalix BioTherapeutics

    Organophosphate Exposure

    phase 1 small molecule completed

    1 trial

  34. PRX-P4-003, (-)-FCF

    Praxis Precision Medicines

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  35. PSA/IL-2/GM-CSF

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 mab active

    1 trial

  36. PT00114-001A

    Protagenic Therapeutics, Inc.new

    Phase I study in healthy male and female volunteers. Intended indication: mood disorders

    phase 1 other active

    1 trial

  37. PTC299

    PTC THERAPEUTICS, INC.

    Leukemia, Myeloid, Acute

    phase 1 small molecule terminated

    1 trial

  38. PTC299

    PTC THERAPEUTICS, INC.

    Metastatic Breast Cancer

    phase 1 small molecule completed

    1 trial

  39. PTC299

    PTC THERAPEUTICS, INC.

    Advanced Cancer

    phase 1 small molecule terminated

    1 trial

  40. PTC596

    PTC THERAPEUTICS, INC.

    High Grade Glioma

    phase 1 small molecule active

    1 trial

  41. PTC596

    PTC THERAPEUTICS, INC.

    Cancer

    phase 1 small molecule completed

    1 trial

  42. PTC:VS-TC

    Istituto Gentili S.r.l.

    Patients who have received an allogeneic haematopoietic stem cell transplant and who have developed post-transplant viral reactivation (CMV, Adenovirus, EBV) resistant to pharmacological therapies.

    phase 1 other active

    1 trial

  43. PTG-100

    Protagonist Therapeutics, Inc

    Celiac Disease

    phase 1 small molecule completed

    1 trial

  44. PTG-300

    Protagonist Therapeutics, Inc

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  45. PTOC1

    Chongqing Precision Biotech Co., Ltd

    Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial

  46. PV-10 (10% rose bengal disodium)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Cancer Metastatic to the Liver

    phase 1 small molecule active

    1 trial

  47. PV-10 (rose bengal disodium 10%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  48. PV-10 (rose bengal disodium, 10%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Melanoma

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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