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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 64 of 99

  1. OP-701

    Oncopeptides AB (publ)

    Recurrent glioblastoma

    phase 1 other active

    1 trial

  2. OPB-31121

    Otsuka Beijing Research Institute

    Non-Hodgkin's Lymphoma(NHL)

    phase 1 small molecule completed

    1 trial

  3. OPB-51602

    Hospital Authority, Hong Kong

    Nasopharyngeal Carcinoma

    phase 1 small molecule terminated

    1 trial

  4. OPC-108459

    Otsuka Beijing Research Institute

    Atrial Fibrillation

    phase 1 small molecule completed

    1 trial

  5. OPC1

    Lineage Cell Therapeutics

    Spinal Cord Injury Cervical

    phase 1 mab active

    1 trial

  6. OPRX-106

    Protalix BioTherapeutics

    Human Volunteer

    phase 1 small molecule completed

    1 trial

  7. ORG-129

    Agomab Therapeutics NV

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  8. ORIC-101

    Topiloric/Uriadec

    Prostatic Neoplasms

    phase 1 small molecule terminated

    1 trial

  9. ORIC-101

    Topiloric/Uriadec

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  10. ORIC-101

    Topiloric/Uriadec

    Solid Tumor

    phase 1 small molecule terminated

    1 trial

  11. ORIC-114

    Topiloric/Uriadec

    Food Effect in Healthy Participants

    phase 1 small molecule completed

    1 trial

  12. ORIC-114 Dose 1 + amivantamab

    Topiloric/Uriadec

    Solid Tumors

    phase 1 small molecule active

    1 trial

  13. ORIC-533

    Topiloric/Uriadec

    Relapsed or Refractory Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  14. ORIC-944

    Topiloric/Uriadec

    Metastatic Prostate Cancer

    phase 1 small molecule active

    1 trial

  15. ORKA-001

    Oruka Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  16. ORKA-002

    Oruka Therapeutics

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  17. OROS-MPH

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 1 small molecule completed

    1 trial

  18. ORX142 Tablets

    Centessa Pharmaceuticals plc

    Excessive Daytime Sleepiness

    phase 1 small molecule active

    1 trial

  19. ORX489 Tablets

    Centessa Pharmaceuticals plc

    Healthy Adult Male and Female Volunteers

    phase 1 small molecule active

    1 trial

  20. Obatoclax mesylate (GX15-070MS)

    Teva Pharma GmbH

    Hematological Malignancies

    phase 1 small molecule completed

    1 trial

  21. Obecabtagene autoleucel (obe-cel)

    Autolus GmbH

    Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial

  22. Obecabtagene autoleucel (obe-cel)

    Autolus GmbH

    Progressive Multiple Sclerosis

    phase 1 mab active

    1 trial

  23. Octreotide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Enterocutaneous Fistulas

    phase 1 small molecule completed

    1 trial

  24. Odronextamab

    Regeneron UK Limited

    B-cell Non-Hodgkins Lymphoma (B-NHL)

    phase 1 small molecule active

    1 trial

  25. Odronextamab multiple dose levels

    Regeneron UK Limited

    Non-Hodgkin Lymphoma

    phase 1 small molecule completed

    1 trial

  26. Olanzapine

    CORCEPT THERAPEUTICS INC

    Antipsychotic-induced Weight Gain

    phase 1 small molecule completed

    1 trial

  27. Olanzapine Extended Release

    Teva Pharma GmbH

    Schizophrenia, Schizoaffective Disorder

    phase 1 small molecule completed

    1 trial

  28. Olaparib tablets, 150 mg

    Sandoz Pty Ltd

    Ovarian Cancer

    phase 1 small molecule completed

    1 trial

  29. Olaratumab

    Eli Lilly and Company

    Malignancy

    phase 1 mab completed

    1 trial

  30. Olezarsen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  31. Olfactory ensheathing cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Infarction, Middle Cerebral Artery

    phase 1 other active

    1 trial

  32. Olinciguat

    Cyclerion Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  33. Ologen Collagen Matrix

    AEON Biopharma

    Congenital Glaucoma

    phase 1 other active

    1 trial

  34. Olomorasib

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  35. Olutasidenib Investigational Agent Administration

    RIGEL PHARMACEUTICALS INC

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  36. Omacetaxine

    Teva Pharma GmbH

    Hematologic Tumors

    phase 1 small molecule completed

    1 trial

  37. Omega 3 fatty acid

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Male Infertility Due to Hypospermatogenesis

    phase 1 small molecule active

    1 trial

  38. Omega-3 fatty acids

    NORTHWEST BIOTHERAPEUTICS INC

    Metabolic Syndrome X

    phase 1 other active

    1 trial

  39. Omeprazole 40 MG

    LEXICON PHARMACEUTICALS, INC.

    Drug-drug Interaction

    phase 1 small molecule completed

    1 trial

  40. Omnitram

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule completed

    1 trial

  41. Onartuzumab

    Hoffmann-La Roche

    Carcinoma, Hepatocellular

    phase 1 small molecule completed

    1 trial

  42. Oncolytic Virus SDJ001

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Malignant Tumor

    phase 1 small molecule active

    1 trial

  43. Ondansetron

    HALOZYME THERAPEUTICS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  44. Ondansetron

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  45. Ondansetron (ODFS)

    Aquestive Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  46. Ondansetron 8 mg ODFS without water

    Aquestive Therapeutics

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  47. One dose of investigational vaccine

    Sinovac Research and Development Co.,

    Hepatitis B

    phase 1 mab completed

    1 trial

  48. Ontamalimab

    Takeda

    Steatohepatitis

    phase 1 small molecule terminated

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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