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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 62 of 99

  1. Nafamostat Mesilate

    BRIGHT MINDS BIOSCIENCES INC.

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  2. Nalbuphine ER

    Trevi Therapeutics

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  3. Nalbuphine HCl solution

    Trevi Therapeutics

    Nalbuphine

    phase 1 small molecule completed

    1 trial

  4. Nalmefene

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 1 small molecule completed

    1 trial

  5. Naloxone

    BRIGHT MINDS BIOSCIENCES INC.

    Drug Overdose

    phase 1 small molecule completed

    1 trial

  6. Naloxone

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-use Disorder

    phase 1 small molecule completed

    1 trial

  7. Naloxone Hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-use Disorder

    phase 1 small molecule terminated

    1 trial

  8. Naltrexone and Bupropion SR

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 1 small molecule completed

    1 trial

  9. Naltrexone implant, 14.4 grams

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule active

    1 trial

  10. Nanosensor

    United Therapeutics Europe Ltd

    MItochondrial Myopathies

    phase 1 other active

    1 trial

  11. Narcan 40 MG/ML Nasal Spray

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Induced Respiratory Depression

    phase 1 small molecule active

    1 trial

  12. NatrunixTM

    XBiotech Germany GmbH

    Pharmacokinetics

    phase 1 mab active

    1 trial

  13. Navitoclax

    AbbVie

    Acute Lymphoblastic Leukemia (ALL)

    phase 1 small molecule completed

    1 trial

  14. Nemonoxacin

    Jian Li

    Kidney Dysfunction

    phase 1 small molecule active

    1 trial

  15. NeoTISLEGA - A phase Ib trial evaluating the...

    The George Institute

    resectable esophagogastric adenocarcinoma

    phase 1 other active

    1 trial

  16. Neoadjuvant chemotherapy

    Hospital Authority, Hong Kong

    Squamous Cell Carcinoma of Oral Cavity

    phase 1 small molecule completed

    1 trial

  17. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Healthy Subjects

    phase 1 small molecule completed

    3 trials

  18. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Advanced Malignant Solid Tumors

    phase 1 small molecule completed

    3 trials

  19. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Neoplasms

    phase 1 small molecule completed

    1 trial

  20. Neratinib (HKI-272)

    PUMA BIOTECHNOLOGY, INC.

    Hepatic Insufficiency

    phase 1 small molecule completed

    1 trial

  21. Neratinib 160 mg

    PUMA BIOTECHNOLOGY, INC.

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  22. Neratinib Pill

    PUMA BIOTECHNOLOGY, INC.

    Gastric Cancer

    phase 1 small molecule active

    1 trial

  23. NeuroRegen scaffold with BMMCs or MSCs transplantation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Spinal Cord Injury

    phase 1 mab active

    1 trial

  24. Nevirapine

    Teva Pharma GmbH

    HIV-1

    phase 1 small molecule completed

    1 trial

  25. New formulation

    GlaxoSmithKline

    Herpes Labialis

    phase 1 small molecule completed

    1 trial

  26. Nezulcitinib (TD-0903) Dose A

    Theravance Biopharma Ireland Umited

    Acute Lung Injury (ALI) Due to Coronavirus Disease-2019 (COVID-19)

    phase 1 small molecule completed

    1 trial

  27. Nicorette Extra Mint 2 mg Gum

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Tobacco Dependence

    phase 1 small molecule completed

    1 trial

  28. Nicotine

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Addiction

    phase 1 small molecule completed

    1 trial

  29. Nicotine

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 1 small molecule completed

    1 trial

  30. Nicotine (Pharmaceutical Productions Inc.)

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Pharmacokinetic Study

    phase 1 small molecule completed

    1 trial

  31. Nicotine Patch

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 1 small molecule completed

    1 trial

  32. Nicotine Pouches

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Pouch Self-Administration

    phase 1 small molecule active

    1 trial

  33. Nicotine Replacement Therapy

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 1 small molecule completed

    1 trial

  34. Nicotine gum (C)

    Century Therapeutics

    Tobacco Use

    phase 1 small molecule completed

    2 trials

  35. Nicotine nasal spray 0.5 mg

    BRIGHT MINDS BIOSCIENCES INC.

    Adverse Childhood Experiences

    phase 1 small molecule active

    1 trial

  36. Nicotine patch

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Addiction

    phase 1 small molecule completed

    1 trial

  37. Nicotine polacrilex

    BRIGHT MINDS BIOSCIENCES INC.

    Depressive Disorder

    phase 1 small molecule completed

    1 trial

  38. Nicotine saline infusion 0.00mcg/kg/s

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 1 small molecule completed

    1 trial

  39. Nicotrol

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 1 small molecule completed

    1 trial

  40. Nifedipine 60 MG Extended Release Oral Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  41. Nimotuzumab

    Biotech Pharmaceutical Co.,

    Solid Tumors

    phase 1 small molecule active

    1 trial

  42. Nimotuzumab and chemotherapy

    Biotech Pharmaceutical Co.,

    Non-small Cell Lung Cancer

    phase 1 small molecule terminated

    1 trial

  43. Niraparib

    Takeda

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  44. Nivolumab

    United Therapeutics Europe Ltd

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  45. Nivolumab

    Iovance Biotherapeutics B.V.

    Melanoma (Skin)

    phase 1 small molecule completed

    1 trial

  46. Nivolumab

    Iovance Biotherapeutics B.V.

    Non-Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  47. Nivolumab

    Nektar Therapeutics UK Limited

    Renal Cell Carcinoma

    phase 1 mab completed

    1 trial

  48. Nivolumab

    Bristol-Myers Squibb

    Melanoma

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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