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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 60 of 99

  1. Molecular imaging with FAPI for diagnosing the CSM4 colorectal cancer subtype

    Disc Medicine

    Colorectal cancer, liver metastases

    phase 1 other active

    1 trial

  2. Mometasone furoate drug formulation (MFF) 1

    BRIGHT MINDS BIOSCIENCES INC.

    Hypersensitivity

    phase 1 small molecule completed

    1 trial

  3. Morphine Sulfate

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule active

    1 trial

  4. Motion analysis of patients

    Hospital Authority, Hong Kong

    Leg Length Discrepancy

    phase 1 other completed

    1 trial

  5. Motivational Interviewing

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 1 other completed

    1 trial

  6. Motivational Network Intervention

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Use

    phase 1 other completed

    1 trial

  7. Mudan granule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Diabetic Peripheral Neuropathy Type 2

    phase 1 small molecule active

    1 trial

  8. Multi-media WINGS

    BRIGHT MINDS BIOSCIENCES INC.

    Intimate Partner Violence

    phase 1 other completed

    1 trial

  9. Mycophenolate Mofetil

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    4 trials

  10. Mycophenolate Mofetil

    BRIGHT MINDS BIOSCIENCES INC.

    Hematopoietic Stem Cell Transplantation

    phase 1 small molecule active

    1 trial

  11. N-Acetylcysteine

    United Therapeutics Europe Ltd

    Mitochondrial Disease

    phase 1 small molecule active

    1 trial

  12. N-acetyl cysteine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  13. N-acetylcysteine

    Ultragenyx UK Limited

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  14. NAL ER

    Trevi Therapeutics

    Healthy Participants

    phase 1 small molecule active

    2 trials

  15. NALTR-17-24

    Lacuna Pharma Pty Ltd

    Alcohol dependence

    phase 1 other active

    1 trial

  16. NAT-022/BIO

    Dr. Falk Pharma GmbH

    Idiopathic or diabetic gastroparesis

    phase 1 other active

    1 trial

  17. NAT-024/BIO

    Dr. Falk Pharma GmbH

    No medical condition.

    phase 1 other active

    1 trial

  18. NBI-1076986-1761

    NEUROCRINE BIOSCIENCES INC

    Movement disorders

    phase 1 other active

    1 trial

  19. NBI-1117570-1769

    NEUROCRINE BIOSCIENCES INC

    Neurological and neuropsychiatric conditions

    phase 1 other active

    1 trial

  20. NBI-6024

    NEUROCRINE BIOSCIENCES INC

    Type 1 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  21. NBI-77860

    NEUROCRINE BIOSCIENCES INC

    Congenital Adrenal Hyperplasia

    phase 1 small molecule terminated

    1 trial

  22. NBI-98854 50 mg capsule

    NEUROCRINE BIOSCIENCES INC

    Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects

    phase 1 small molecule completed

    1 trial

  23. NBI-98854 50 mg capsule once daily

    NEUROCRINE BIOSCIENCES INC

    Effect of Ketoconazole on the PK of NBI-98854 in Healthy Subjects

    phase 1 small molecule completed

    1 trial

  24. NC2022-01

    Disc Medicine

    Glioblastoma

    phase 1 other active

    1 trial

  25. NCO-48 Fumarate

    LIGAND PHARMACEUTICALS INC

    Hepatitis B

    phase 1 small molecule completed

    1 trial

  26. NCO-48 Fumarate 4 mg

    LIGAND PHARMACEUTICALS INC

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  27. ND-003 40mg

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule active

    1 trial

  28. NDV-3 vaccine with alum IM

    United Therapeutics Europe Ltd

    Staphylococcal Infections

    phase 1 mab completed

    1 trial

  29. NDX-1017

    BRIGHT MINDS BIOSCIENCES INC.

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  30. NEPA-23-01

    Helsinn Birex Pharmaceuticals

    Healthy volunteers

    phase 1 other active

    1 trial

  31. NFC-1

    Avalo Therapeutics

    22q11.2 Deletion Syndrome

    phase 1 small molecule completed

    1 trial

  32. NFC-1

    Avalo Therapeutics

    Attention-deficit Hyperactivity Disorder (ADHD)

    phase 1 small molecule completed

    1 trial

  33. NFC-1 100 mg

    Avalo Therapeutics

    Attention Deficit Disorder With Hyperactivity

    phase 1 small molecule completed

    1 trial

  34. NGGT002 Injection

    The First People's Hospital of Lianyungang

    Phenylketonurias

    phase 1 gene therapy active

    1 trial

  35. NIO752B12201

    Novartis Pharmaceuticals

    Alzheimer’s Disease

    phase 1 other active

    1 trial

  36. NITRAIS 03/2024

    Lacuna Pharma Pty Ltd

    healthy subjects

    phase 1 other active

    1 trial

  37. NK510

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NSCLC

    phase 1 small molecule active

    1 trial

  38. NKTR-102

    Nektar Therapeutics UK Limited

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  39. NKTR-181

    Nektar Therapeutics UK Limited

    Moderate to Severe Chronic Pain

    phase 1 small molecule terminated

    1 trial

  40. NKTR-214

    Nektar Therapeutics UK Limited

    Advanced Cancer

    phase 1 mab completed

    1 trial

  41. NKTR-214 (Cohort A)

    INOVIO PHARMACEUTICALS, INC.

    Metastatic Castration-resistant Prostate Cancer

    phase 1 small molecule completed

    1 trial

  42. NKTR-255

    Nektar Therapeutics UK Limited

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  43. NL202100762

    Disc Medicine

    Patients with stage II-IV high risk diffuse large B-cell lymphoma, defined as international prognostic index > 2, Lymphoma

    phase 1 other active

    1 trial

  44. NL66938.041.19

    Disc Medicine

    colorectal liver metastases

    phase 1 other active

    1 trial

  45. NL85300.041.23

    Disc Medicine

    Metastatic or unresectable solid malignancies. Standard of care treatment options must not be available or not be considered feasible. Patients must have a primary tumor or metastasis that is suitable for HIFU-HT treatment.

    phase 1 other active

    1 trial

  46. NM1F Injection

    TG THERAPEUTICS, INC.

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  47. NMRA-323511

    Neumora Therapeutics

    Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  48. NN1436-7615

    NovoThirteen

    Type 2 diabetes

    phase 1 other active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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