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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 6 of 99

  1. 45-mg hydrocodone bitartrate extended-release tablet (crushed or intact)

    Teva Pharma GmbH

    Drug Abuse

    phase 1 small molecule completed

    1 trial

  2. 480 mg Piperaquine phosphate

    CNS Pharmaceuticals

    Malaria

    phase 1 small molecule completed

    1 trial

  3. 4D-110

    4D Molecular Therapeutics

    Choroideremia

    phase 1 mab active

    1 trial

  4. 5 mg/500 mg Glipizide Metformin Hydrochloride Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  5. 5 mg/500 mg METAGLIP™ Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  6. 50 mg LX3305 QD

    LEXICON PHARMACEUTICALS, INC.

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial

  7. 500 mg GLPG1837 as oral suspension

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  8. 500 mg [14C]-LX1606

    LEXICON PHARMACEUTICALS, INC.

    Carcinoid Syndrome

    phase 1 small molecule completed

    1 trial

  9. 50mg Ezogabine/retigabine

    GlaxoSmithKline

    Epilepsy

    phase 1 small molecule completed

    1 trial

  10. 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  11. 608

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Moderate to Severe Plaque Psoriasis

    phase 1 small molecule active

    1 trial

  12. 609A

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Solid Tumors

    phase 1 small molecule active

    2 trials

  13. 610

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    add-on Maintenance Treatment of Patients With Severe Eosinophilic Asthma

    phase 1 small molecule active

    1 trial

  14. 610 30mg group

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Asthma

    phase 1 small molecule active

    1 trial

  15. 626

    Jian Li

    Healthy Subjects (HS)

    phase 1 small molecule active

    1 trial

  16. 626

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Subjects (HS)

    phase 1 small molecule active

    1 trial

  17. 627

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Subjects (HS)

    phase 1 mab active

    1 trial

  18. 63733657EDI1003

    Janssen-Cilag International N.V.

    Alzheimer's Disease (Healthy Participants)

    phase 1 other active

    1 trial

  19. 64007957MMY1008

    Janssen-Cilag International N.V.

    Relapsed/Refractory Multiple Myeloma

    phase 1 other active

    1 trial

  20. 64264681LYM1001

    Janssen-Cilag International N.V.

    non-Hodgkin lymphoma and chronic lymphocytic leukemia

    phase 1 other active

    1 trial

  21. 64264681LYM1002

    Janssen-Cilag International N.V.

    non-Hodgkin lymphoma and chronic lymphocytic leukemia

    phase 1 other active

    1 trial

  22. 64407564MMY1002

    Janssen-Cilag International N.V.

    Multiple myeloma

    phase 1 other active

    1 trial

  23. 64407564MMY1004

    Janssen-Cilag International N.V.

    multiple myeloma

    phase 1 other active

    1 trial

  24. 64407564MMY1005

    Janssen-Cilag International N.V.

    Relapsed or Refractory Multiple Myeloma

    phase 1 other active

    1 trial

  25. 64619178EDI1001

    Janssen-Cilag International N.V.

    Previously treated lymphoma (blood cancer) or solid tumors and NHL

    phase 1 other active

    1 trial

  26. 64Cu-DOTA-TLX592

    Telix Innovations

    Metastatic Prostate Cancer

    phase 1 small molecule completed

    1 trial

  27. 67652000PCR1001

    Janssen-Cilag International N.V.

    Metastatic castration-resistant prostate cancer (mCRPC)

    phase 1 other active

    1 trial

  28. 67856633LYM1001

    Janssen-Cilag International N.V.

    Non-Hodgkin lymphoma and chronic lymphocytic leukemia

    phase 1 other active

    1 trial

  29. 67856633LYM1002

    Janssen-Cilag International N.V.

    Non-Hodgkin lymphoma and chronic lymphocytic leukemia

    phase 1 other active

    1 trial

  30. 67896062PAH1011

    Lacuna Pharma Pty Ltd

    Pulmonary Arterial Hypertension

    phase 1 other active

    1 trial

  31. 67953964MDD1010

    Janssen-Cilag International N.V.

    Healthy Adult Participants

    phase 1 other active

    1 trial

  32. 67953964MDD1011

    Janssen-Cilag International N.V.

    Healthy Adult Participants.

    phase 1 other active

    1 trial

  33. 68-Ga PSMA11

    Telix Innovations

    Prostate Adenocarcinoma

    phase 1 small molecule active

    1 trial

  34. 68GA-FAPI-46

    Disc Medicine

    Peritoneal metastases

    phase 1 small molecule active

    1 trial

  35. 68Ga-AAZTA-NI-093

    The First People's Hospital of Lianyungang

    Prostate Cancer (Adenocarcinoma)

    phase 1 small molecule active

    1 trial

  36. 68Ga-BNU-PSMA

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 other active

    1 trial

  37. 68Ga-DOTA-FAPI, 177Lu-DOTA-FAPI

    The First People's Hospital of Lianyungang

    177Lu-DOTA-FAPI

    phase 1 small molecule active

    1 trial

  38. 68Ga-DOTA/NOTA-FAPI-04

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 small molecule active

    1 trial

  39. 68Ga-FAPI-04

    The First People's Hospital of Lianyungang

    Liver Fibrosis

    phase 1 small molecule active

    1 trial

  40. 68Ga-FAPI-04

    Jian Li

    Fibrosis

    phase 1 small molecule active

    1 trial

  41. 68Ga-FAPI-Biotin

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 small molecule active

    1 trial

  42. 68Ga-JH04

    The First People's Hospital of Lianyungang

    Malignant Neoplasm

    phase 1 small molecule active

    1 trial

  43. 68Ga-JH12

    The First People's Hospital of Lianyungang

    Malignant Neoplasm

    phase 1 small molecule active

    1 trial

  44. 68Ga-MGS5

    The First People's Hospital of Lianyungang

    Medullary Thyroid Carcinoma

    phase 1 small molecule active

    1 trial

  45. 68Ga-NNS309

    Novartis Pharmaceuticals

    Pancreatic Ductal Adenocarcinoma

    phase 1 small molecule active

    1 trial

  46. 68Ga-NODAGA-SNA006

    The First People's Hospital of Lianyungang

    Solid Tumor

    phase 1 mab completed

    1 trial

  47. 68Ga-NOTA-MAL-Cys39-exendin-4

    The First People's Hospital of Lianyungang

    Insulinoma

    phase 1 small molecule active

    1 trial

  48. 68Ga-PSMA-11

    The First People's Hospital of Lianyungang

    Prostate Cancer

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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