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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 55 of 99

  1. Liraglutide injection,RD12014

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes

    phase 1 small molecule completed

    1 trial

  2. Lisdexamfetamine Dimesylate

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  3. Lisdexamfetamine Dimesylate

    Takeda

    Healthy

    phase 1 small molecule terminated

    1 trial

  4. Lisdexamfetamine Dimesylate (LDX)

    Takeda

    Attention-Deficit Hyperactivity Disorder

    phase 1 small molecule completed

    1 trial

  5. Litapiprant Tablet

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Asthma

    phase 1 small molecule completed

    1 trial

  6. Livmoniplimab, Budigalimab

    AbbVie Deutschland GmbH & Co. KG

    Locally Advanced or Metastatic Solid Tumors, Solid Tumors

    phase 1 small molecule active

    1 trial

  7. Lobeline

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 1 small molecule active

    1 trial

  8. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  9. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Related Disorders

    phase 1 small molecule terminated

    1 trial

  10. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 1 small molecule completed

    1 trial

  11. Lofexidine (granules for reconstitution)

    BRIGHT MINDS BIOSCIENCES INC.

    Normal Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  12. Lofexidine HCl

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  13. Lofexidine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Normal Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  14. Lofexidine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Normal Healthy Volunteers Will be Treated With Lofexidine to Understand the Absolute Bioavailability and Mass Balance Recovery of the Product

    phase 1 small molecule completed

    1 trial

  15. Loncastuximab Tesirine

    ADC Therapeutics SA

    B-Cell Non-Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  16. Loncastuximab Tesirine and Acalabrutinib

    ADC Therapeutics SA

    Chronic Lymphocytic Leukemia

    phase 1 small molecule active

    1 trial

  17. Loncastuximab Tesirine and Durvalumab

    ADC Therapeutics SA

    Diffuse Large B-Cell Lymphoma

    phase 1 small molecule terminated

    1 trial

  18. Loncastuximab tesirine and rituximab (Lonca-R)

    ADC Therapeutics SA

    Central Nervous System Lymphoma

    phase 1 small molecule active

    1 trial

  19. Lopinavir/Ritonavir 200 mg/50 mg Film Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  20. Lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule completed

    1 trial

  21. Losartan

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  22. Losartan potassium

    United Therapeutics Europe Ltd

    Emotional Processing

    phase 1 small molecule active

    1 trial

  23. Losartan potassium 50mg

    United Therapeutics Europe Ltd

    Emotional Processing

    phase 1 small molecule active

    1 trial

  24. Losartan potassium 50mg

    United Therapeutics Europe Ltd

    Social Cognition

    phase 1 small molecule active

    1 trial

  25. Losartan potassium/Hydrochlorothiazide

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  26. Losmapimod 15 mg oral tablet

    Fulcrum Therapeutics

    Healthy Adult Subjects

    phase 1 small molecule completed

    1 trial

  27. Low Density Lipoprotein Receptor mRNA Exosomes

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Familial Hypercholesterolemia

    phase 1 mab active

    1 trial

  28. Low Dose MSH2-/- tumor cell vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    pMMR/MSS Advanced Colorectal Cancer

    phase 1 mab active

    1 trial

  29. Low Dose REN001

    OnKure Therapeutics

    Fatty Acid Oxidation Disorders

    phase 1 small molecule completed

    1 trial

  30. Low Level Laser Therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Orthodontic Appliance Complication

    phase 1 other completed

    1 trial

  31. Low dose ET019002- T Cells

    The First People's Hospital of Lianyungang

    B-Cell Malignancies

    phase 1 mab active

    1 trial

  32. Low-dose RSV mRNA vaccine

    Sinovac Research and Development Co.,

    RSV

    phase 1 mab active

    1 trial

  33. Lu AF28996

    H. Lundbeck A/S

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  34. Lu AF28996 in Patients With Parkinson's Disease

    H. Lundbeck A/S

    Parkinson's Disease

    phase 1 other active

    1 trial

  35. Lubiprostone

    Takeda

    Other Constipation

    phase 1 small molecule completed

    1 trial

  36. Lubiprostone

    Takeda

    Chronic Constipation, Methanogenesis

    phase 1 small molecule completed

    1 trial

  37. Lucid-21-302

    Quantum Biopharma

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  38. Lucid-21-302

    Quantum Biopharma

    Heathy Participants

    phase 1 small molecule completed

    1 trial

  39. Lumason Contrast-Enhanced Ultrasound

    United Therapeutics Europe Ltd

    Kidney Transplantation

    phase 1 small molecule terminated

    1 trial

  40. Lumason® contrast agent

    United Therapeutics Europe Ltd

    Mitochondrial Myopathies

    phase 1 small molecule active

    1 trial

  41. Lurbinectedin

    Jazz Pharmaceuticals Ireland Limited

    Extensive Stage Lung Small Cell Carcinoma

    phase 1 small molecule active

    1 trial

  42. Lysogenic HSV virus.

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HNSCC

    phase 1 mab active

    1 trial

  43. M-27312-01

    Almirall, S.A.

    Inflammatory diseases

    phase 1 other active

    1 trial

  44. M15-531

    AbbVie Deutschland GmbH & Co. KG

    Myelodysplastic Syndromes (MDS)

    phase 1 other active

    1 trial

  45. M16-573

    AbbVie Deutschland GmbH & Co. KG

    Patients with relapsed or refractory solid tumors, including: Small cell lung cancer (SCLC); Non-small cell cancer (NSCLC); Breast cancer

    phase 1 other active

    1 trial

  46. M19-753

    AbbVie Deutschland GmbH & Co. KG

    Myelofibrosis, Myeloproliferative Neoplasms

    phase 1 small molecule active

    1 trial

  47. M20-258

    AbbVie Deutschland GmbH & Co. KG

    Multiple Myeloma

    phase 1 other active

    1 trial

  48. M21-404

    AbbVie Deutschland GmbH & Co. KG

    Advanced solid tumors including (but not limited to), non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), gastric/gastroesophageal junction adenocarcinoma (GEA), colorectal cancer (CRC), and renal cell carcinoma (RCC)

    phase 1 other active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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