Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 54 of 99

  1. LY3493269

    Eli Lilly and Company

    Healthy

    phase 1 small molecule terminated

    1 trial

  2. LY3493269 - SC

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  3. LY3532226

    Eli Lilly and Company

    Obesity

    phase 1 small molecule completed

    1 trial

  4. LY3537021

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  5. LY3819469

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  6. LY4006896

    Eli Lilly and Company

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  7. Lamivudine

    GlaxoSmithKline

    Hepatitis B, Chronic

    phase 1 small molecule completed

    1 trial

  8. Lamotrigine

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  9. Lamotrigine 25 mg Chewable Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  10. Lamotrigine Extended Release

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  11. Lanadelumab

    Takeda

    COVID-19 Pneumonia

    phase 1 small molecule terminated

    1 trial

  12. Lanadelumab

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  13. Lanraplenib.

    Gilead Sciences Ireland UC

    Inflammatory Disease

    phase 1 small molecule completed

    1 trial

  14. Lansoprazole

    Takeda

    Gastroesophageal Reflux Disease

    phase 1 small molecule completed

    2 trials

  15. Lansoprazole

    PUMA BIOTECHNOLOGY, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  16. Lansoprazole

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    3 trials

  17. Lansoprazole capsules

    The First People's Hospital of Lianyungang

    Effect of Drugs

    phase 1 small molecule completed

    1 trial

  18. Lanthanum carbonate Granule Formulation

    Takeda

    End Stage Renal Disease

    phase 1 small molecule completed

    1 trial

  19. Larotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Esophageal Cancer

    phase 1 small molecule active

    1 trial

  20. Larotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  21. Larotrectinib

    Hospital Authority, Hong Kong

    High Grade Glioma

    phase 1 small molecule active

    1 trial

  22. Leflunomide 20 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  23. Lenalidomide (CC-5013)

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  24. Lenalidomide or Pomalidomide

    ONCOLYTICS BIOTECH INC

    Multiple Myeloma

    phase 1 small molecule active

    1 trial

  25. Lendormin tablet

    Boehringer Ingelheim

    Healthy

    phase 1 small molecule completed

    1 trial

  26. Lenvatinib

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma Stage IIIa

    phase 1 small molecule active

    1 trial

  27. Letrozole

    Context Therapeutics

    Metastatic Breast Cancer

    phase 1 small molecule terminated

    1 trial

  28. Leukocyte Interleukin, Injection 200IU

    United Therapeutics Europe Ltd

    Condyloma

    phase 1 small molecule terminated

    1 trial

  29. Levetiracetam

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    4 trials

  30. Levodopa

    Blackmores Limited

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  31. Levodopa 250mg and Carbidopa 25mg Test Drug tablet

    Laboratorios Tillomed Spain S.L.U

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  32. Levodopa Cyclops®

    BRIGHT MINDS BIOSCIENCES INC.

    Parkinson

    phase 1 other completed

    1 trial

  33. Liberase Enzyme (Roche)

    Blackmores Limited

    Pulmonary Alveolar Proteinosis

    phase 1 small molecule active

    1 trial

  34. Lidocaine patch

    BRIGHT MINDS BIOSCIENCES INC.

    Heat Effect

    phase 1 small molecule completed

    1 trial

  35. Lifestyle counseling

    BRIGHT MINDS BIOSCIENCES INC.

    Adherence

    phase 1 other completed

    1 trial

  36. Lifileucel (LN-144)

    Iovance Biotherapeutics B.V.

    Metastatic Melanoma

    phase 1 mab active

    1 trial

  37. Lifileucel (LN-144/LN-145)

    Iovance Biotherapeutics B.V.

    Uveal Melanoma

    phase 1 mab active

    1 trial

  38. Lifirafenib

    BEONE MEDICINES AUS PTY LTD

    Solid Tumor, Adult

    phase 1 small molecule completed

    1 trial

  39. Light Power Density and Light Duration 40 mW/cm²*1000s

    The First People's Hospital of Lianyungang

    Healthy Adult Subjects

    phase 1 other completed

    1 trial

  40. Linperlisib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 small molecule terminated

    1 trial

  41. Linperlisib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed/Refractory Large Granular T Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  42. Lintuzumab AC 225

    Actinium Pharmaceuticals

    Refractory Multiple Myeloma

    phase 1 small molecule terminated

    1 trial

  43. Lipegfilgrastim

    Teva Pharma GmbH

    Ewing Family of Tumors, Rhabdomyosarcoma

    phase 1 small molecule completed

    1 trial

  44. Lipoaspiration

    REVIVA PHARMACEUTICALS HOLDINGS, INC.

    Hereditary Corneal Dystrophy

    phase 1 other active

    1 trial

  45. Liposomal Bupivacaine 13.3

    Pacira Ireland Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  46. Liposomal Mitoxantrone Hydrochloride dose level 1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  47. Liposomal bupivacaine

    United Therapeutics Europe Ltd

    Pain, Postoperative

    phase 1 small molecule completed

    1 trial

  48. Lipotecan

    Taiwan Liposome Company

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.