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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 52 of 99

  1. KYV-101 anti-CD19 CAR-T cell therapy

    Kyverna Therapeutics

    Multiple Sclerosis

    phase 1 mab active

    1 trial

  2. Kang Guan Recipe (Treat)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Coronavirus Disease 2019

    phase 1 other completed

    1 trial

  3. Kangdaprevir Sodium Tablet

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Chronic Hepatitis c

    phase 1 small molecule completed

    1 trial

  4. Ketamine

    United Therapeutics Europe Ltd

    Acute Depression

    phase 1 small molecule terminated

    1 trial

  5. Ketamine

    Takeda

    Ketamine-Induced Brain Activity Changes

    phase 1 small molecule completed

    1 trial

  6. Ketamine

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  7. Ketamine (Ketalar)

    Grace Therapeutics

    Pain

    phase 1 small molecule active

    1 trial

  8. Ketamine (Ketalar) Dose Level 1

    Grace Therapeutics

    Pain, Postoperative

    phase 1 small molecule completed

    1 trial

  9. Ketorolac

    United Therapeutics Europe Ltd

    Pain, Post-operative

    phase 1 small molecule completed

    1 trial

  10. Keverprazan

    The First People's Hospital of Lianyungang

    Helicobacter Pylori Infection

    phase 1 small molecule active

    1 trial

  11. Kindolor Tosylate

    BRIGHT MINDS BIOSCIENCES INC.

    Chronic Pain

    phase 1 small molecule terminated

    1 trial

  12. Kristalose

    CUMBERLAND PHARMACEUTICALS INC

    Bowel Evacuant Prior to Colonoscopy

    phase 1 small molecule completed

    1 trial

  13. Kukoamine B Mesilate

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 small molecule completed

    1 trial

  14. L-dopa / carbidopa / entacapone (LCE)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Abuse

    phase 1 small molecule completed

    1 trial

  15. LA/BRP/02/25

    Lacuna Pharma Pty Ltd

    Androgenetic alopecia

    phase 1 other active

    1 trial

  16. LACOS-06-23

    Lacuna Pharma Pty Ltd

    Epileptic seizures

    phase 1 other active

    1 trial

  17. LAMOT-04-24

    Lacuna Pharma Pty Ltd

    Bipolar disorder, Epilepsy

    phase 1 other active

    1 trial

  18. LB-100 for Injection

    LIXTE BIOTECHNOLOGY HOLDINGS, INC.

    Tumors

    phase 1 small molecule completed

    1 trial

  19. LB1901

    Nanjing Legend Biotech Co.

    T-Cell Lymphoma

    phase 1 mab active

    1 trial

  20. LB1908

    Nanjing Legend Biotech Co.

    Gastric Cancer

    phase 1 mab active

    1 trial

  21. LB2102

    Nanjing Legend Biotech Co.

    Small Cell Lung Cancer Extensive Stage

    phase 1 mab active

    1 trial

  22. LBR-101 IV

    Teva Pharma GmbH

    Bioavailability and Pharmacokinetics

    phase 1 mab completed

    1 trial

  23. LBT-3627

    Biotech Pharmaceutical Co.,

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  24. LCAR-AIO Cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Lymphocytic Leukemia

    phase 1 mab terminated

    1 trial

  25. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Multiple Sclerosis (MS)

    phase 1 mab active

    1 trial

  26. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 mab active

    1 trial

  27. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab terminated

    1 trial

  28. LCAR-AIO cells product

    Nanjing Legend Biotech Co.

    B-cell Lymphoma Recurrent

    phase 1 mab terminated

    1 trial

  29. LCAR-AMDR Cells Product

    Nanjing Legend Biotech Co.

    Acute Myeloid Leukemia

    phase 1 mab terminated

    1 trial

  30. LCAR-B4822M CAR-T Cell Immunotherapy

    Nanjing Legend Biotech Co.

    Refractory or Relapsed Multiple Myeloma

    phase 1 small molecule active

    1 trial

  31. LCAR-BCDR cells product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Multiple Myeloma

    phase 1 mab terminated

    1 trial

  32. LCAR-BCX cells product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Multiple Myeloma

    phase 1 mab active

    1 trial

  33. LCAR-C182A cells

    Nanjing Legend Biotech Co.

    Gastric Cancer

    phase 1 mab terminated

    1 trial

  34. LCAR-C18S cells

    Nanjing Legend Biotech Co.

    Solid Tumors, Adult

    phase 1 mab terminated

    1 trial

  35. LCAR-G08 cells

    Nanjing Legend Biotech Co.

    Advanced Gastrointestinal Tumors

    phase 1 mab terminated

    1 trial

  36. LCAR-HL30 cells

    Nanjing Legend Biotech Co.

    Hodgkin's Lymphoma

    phase 1 mab active

    1 trial

  37. LCAR-M23 cells

    Nanjing Legend Biotech Co.

    Epithelial Ovarian Cancer

    phase 1 mab terminated

    1 trial

  38. LD and GC012F CAR-T Cell Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial

  39. LDK378

    Novartis Pharmaceuticals

    Anaplastic Lymphoma Kinase (ALK)

    phase 1 small molecule completed

    1 trial

  40. LDT600 (Telbivudine)

    Novartis Pharmaceuticals

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  41. LDX + Venlafaxine XR

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  42. LDX-HV-101

    Dompe' Farmaceutici S.p.A.

    Ocular inflammatory conditions

    phase 1 other active

    1 trial

  43. LE 1102

    Pharming Technologies B.V.

    Activated Phosphoinositide 3-Kinase Delta Syndrome

    phase 1 small molecule active

    1 trial

  44. LE 5101

    Pharming Technologies B.V.

    Activated Phosphoinositide 3-Kinase Delta Syndrome

    phase 1 other active

    1 trial

  45. LE 6101

    Pharming Technologies B.V.

    Activated Phosphoinositide 3-Kinase Delta Syndrome

    phase 1 other active

    1 trial

  46. LEE011

    Novartis Pharmaceuticals

    Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer

    phase 1 small molecule completed

    1 trial

  47. LENVIMA hard capsules for Advanced Renal Cell Carcinoma

    AstraZeneca AB

    Advanced Renal Cell Carcinoma

    phase 1 small molecule active

    1 trial

  48. LGD-6972

    LIGAND PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    2 trials

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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