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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 51 of 99

  1. Jianpi Qinghua granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nonerosive Reflux Disease

    phase 1 small molecule active

    1 trial

  2. Jiedu Tongluo granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Post-stroke Depression

    phase 1 small molecule completed

    1 trial

  3. Jiu-wei-zhen-xiao Granule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  4. KAI-9531

    Kailera Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  5. KB301

    Krystal Biotech Netherlands B.V.

    Skin Roughness

    phase 1 mab active

    1 trial

  6. KB407 (Nebulization)

    Krystal Biotech Netherlands B.V.

    Cystic Fibrosis

    phase 1 mab active

    2 trials

  7. KB408 (Nebulization)

    Krystal Biotech Netherlands B.V.

    Alpha 1-Antitrypsin Deficiency

    phase 1 small molecule active

    1 trial

  8. KCP-330

    Karyopharm Therapeutics Inc

    Sarcoma

    phase 1 small molecule completed

    1 trial

  9. KFA115

    Novartis Pharmaceuticals

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule active

    1 trial

  10. KHK6640

    KYOWA KIRIN AUSTRALIA PTY LTD

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  11. KIH24001

    The George Institute

    Alzheimer´s disease

    phase 1 other active

    1 trial

  12. KISIMA-02 vaccine-based immunotherapy for patients with pancreatic cancer

    Boehringer Ingelheim

    G12D/G12V Pancreatic Ductal Adenocarcinoma

    phase 1 other active

    1 trial

  13. KK-LC-1 TCR-T cells

    Iovance Biotherapeutics B.V.

    Gastric Cancer

    phase 1 mab active

    1 trial

  14. KK8123

    KYOWA KIRIN AUSTRALIA PTY LTD

    X-linked hypophosphatemia.

    phase 1 small molecule active

    1 trial

  15. KM023-101

    Lacuna Pharma Pty Ltd

    Olmsted syndrome

    phase 1 other active

    1 trial

  16. KN-8701/KIN2787CI101

    Pierre Fabre Medicament

    Participants with BRAF and/or NRAS mutation positive tumors

    phase 1 other active

    1 trial

  17. KNX100

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  18. KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

    Kura Oncology

    Pancreatic Ductal Adeno Carcinoma, Colorectal Cancer, Non- Small Cell Lung Cancer (NSCLC), Renal Cell Carcinoma

    phase 1 other active

    1 trial

  19. KO-947

    Kura Oncology

    Advanced Malignant Neoplasm

    phase 1 small molecule terminated

    1 trial

  20. KO-MEN-008

    Kura Oncology

    Relapsed and/or refractory Acute Myeloid Leukemia

    phase 1 other active

    1 trial

  21. KPL-404

    Kiniksa Pharmaceuticals International, plc

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  22. KPT-330

    Karyopharm Therapeutics Inc

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  23. KPT-330

    Karyopharm Therapeutics Inc

    Relapsed Acute Lymphoblastic Leukemia (ALL)

    phase 1 small molecule active

    1 trial

  24. KPT-330

    Karyopharm Therapeutics Inc

    Hematological Malignancies

    phase 1 small molecule completed

    1 trial

  25. KPT-330

    Karyopharm Therapeutics Inc

    Diffuse Large B-Cell Lymphoma

    phase 1 small molecule completed

    1 trial

  26. KPT-9274

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  27. KPT-9274

    Karyopharm Therapeutics Inc

    Solid Tumors

    phase 1 small molecule terminated

    1 trial

  28. KRAS Vaccine with Poly-ICLC adjuvant

    United Therapeutics Europe Ltd

    Colorectal Cancer

    phase 1 small molecule active

    1 trial

  29. KSH01 injection

    TScan Therapeutics

    TCR-T Cells

    phase 1 small molecule active

    1 trial

  30. KSH01 injection

    TScan Therapeutics

    Solid Tumor

    phase 1 small molecule active

    1 trial

  31. KSHN001126 150mg

    Amneal Pharma Europe Ltd

    Healthy Postmenopausal Women

    phase 1 small molecule completed

    1 trial

  32. KSV01 Injection

    TScan Therapeutics

    Non-Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  33. KSV01 Injection

    TScan Therapeutics

    B-ALL

    phase 1 small molecule active

    1 trial

  34. KSX01-TCRT injection

    TScan Therapeutics

    TCR-T Cells

    phase 1 small molecule active

    1 trial

  35. KT-253

    Kymera Therapeutics

    Myeloid Malignancies

    phase 1 small molecule completed

    1 trial

  36. KT-333

    Kymera Therapeutics

    Non Hodgkin Lymphoma (NHL)

    phase 1 small molecule completed

    1 trial

  37. KT-413

    Kymera Therapeutics

    Non Hodgkin Lymphoma

    phase 1 small molecule completed

    1 trial

  38. KT-474/Placebo

    Kymera Therapeutics

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  39. KT-579

    Kymera Therapeutics

    Healthy Participants

    phase 1 small molecule active

    1 trial

  40. KT-621

    Kymera Therapeutics

    Healthy Participants Study

    phase 1 small molecule completed

    1 trial

  41. KT-US-499-0150

    Lacuna Pharma Pty Ltd

    Relapsed and/or Refractory B-cell Lymphoma

    phase 1 other active

    1 trial

  42. KVD824

    Kalvista Pharmaceuticals (Ireland) Limited

    Hereditary Angioedema

    phase 1 small molecule completed

    1 trial

  43. KVD824 Prototype 1 modified-release tablet

    Kalvista Pharmaceuticals (Ireland) Limited

    Hereditary Angioedema

    phase 1 small molecule completed

    1 trial

  44. KXV01 TCR Lentinvivo Injection

    TScan Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule active

    2 trials

  45. KXV01 TCR Lentinvivo Injection

    The First People's Hospital of Lianyungang

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  46. KXV01 TCR Lentinvivo Injection

    The First People's Hospital of Lianyungang

    Advanced Solid Cancer

    phase 1 small molecule active

    1 trial

  47. KYV-101

    Kyverna Therapeutics

    Idiopathic Inflammatory Myopathies

    phase 1 small molecule active

    1 trial

  48. KYV-101 (Biological) - 0.33 ×10^8 cells

    Kyverna Therapeutics

    Progressive Multiple Sclerosis

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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