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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 50 of 99

  1. Ivosidenib

    Agios Netherlands B.V.

    IDH1 Mutation Myeloid Neoplasms

    phase 1 small molecule completed

    1 trial

  2. Ixazomib

    Takeda

    Glioblastoma

    phase 1 small molecule completed

    1 trial

  3. Ixazomib

    Takeda

    Lupus Nephritis

    phase 1 small molecule terminated

    1 trial

  4. Ixazomib

    Takeda

    Relapsed and Refractory Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  5. Ixazomib

    Takeda

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  6. Ixazomib

    Takeda

    Light-Chain Amyloidosis

    phase 1 small molecule completed

    1 trial

  7. Ixazomib

    Takeda

    Precursor Cell Lymphoblastic Leukemia-lymphoma

    phase 1 small molecule terminated

    1 trial

  8. Ixazomib (NINLARO®) capsules / Matching placebo capsules

    Takeda

    Relapsing Remitting Multiple Sclerosis

    phase 1 small molecule active

    1 trial

  9. Ixazomib 2.5 mg

    Takeda

    Nonhematologic Malignancies

    phase 1 small molecule completed

    1 trial

  10. J1I-MC-GZQF

    Eli Lilly Co.

    Type 2 Diabetes Mellitus

    phase 1 other active

    1 trial

  11. J1I-MC-GZQG

    Eli Lilly Co.

    Diabetes Mellitus

    phase 1 other active

    1 trial

  12. J2S-MC-GZML

    Eli Lilly Co.

    Healthy, Hepatic Insufficiency

    phase 1 other active

    1 trial

  13. J3L-MC-EZEH

    Eli Lilly Co.

    Normal Hepatic Function and Mild, Moderate, or Severe Hepatic Impairment

    phase 1 other active

    1 trial

  14. J3R-MC-YDAH

    Eli Lilly Co.

    Participants with Mild, Moderate, or Severe Hepatic Impairment and Participants with Normal Hepatic Function

    phase 1 other active

    1 trial

  15. J4P-MC-IYAB

    Eli Lilly Co.

    Type 1 Diabetes Mellitus

    phase 1 other active

    1 trial

  16. J5J-OX-JZZA

    Eli Lilly Co.

    KRAS G12D-mutant solid tumors.

    phase 1 other active

    1 trial

  17. J5Q-OX-JRDA

    Eli Lilly Co.

    Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, Colorectal Cancer, Advanced Solid Tumor Metastatic Solid Tumor, PanKRAS.

    phase 1 other active

    1 trial

  18. J6B-MC-YKAA

    Eli Lilly Co.

    Healthy, Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2

    phase 1 other active

    1 trial

  19. J6I-MC-OWAA

    Eli Lilly Co.

    Sporadic Amyotrophic Lateral Sclerosis

    phase 1 other active

    1 trial

  20. JADE101

    Jade Biosciences

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  21. JADE101

    Jade Biosciences

    Healthy Volunteers (HV)

    phase 1 small molecule active

    1 trial

  22. JADE201

    Jade Biosciences

    Rhematoid Arthritis

    phase 1 small molecule active

    1 trial

  23. JANX007

    Janux Therapeutics

    Prostate Cancer

    phase 1 mab active

    1 trial

  24. JANX008

    Janux Therapeutics

    Non-Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  25. JANX011

    Janux Therapeutics

    Autoimmune

    phase 1 small molecule active

    1 trial

  26. JANX014

    Janux Therapeutics

    Prostate Cancer

    phase 1 mab active

    1 trial

  27. JDtic

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule terminated

    1 trial

  28. JIO-MC-JZHD

    Eli Lilly Co.

    Neuroblastoma

    phase 1 other active

    1 trial

  29. JNJ-53718678

    Janssen Cilag International NV

    Respiratory Syncytial Virus Infections

    phase 1 small molecule terminated

    1 trial

  30. JNJ-56021927

    Janssen Cilag International NV

    Prostatic Neoplasms, Castration-Resistant

    phase 1 small molecule completed

    1 trial

  31. JR-441

    Lacuna Pharma Pty Ltd

    Mucopolysaccharidosis type IIIA (MPS IIIA)

    phase 1 small molecule active

    1 trial

  32. JR8603

    JiaRay Group

    Solid Tumors

    phase 1 small molecule active

    1 trial

  33. JSB462

    Novartis Pharmaceuticals

    Metastatic Prostate Cancer (mCRPC)

    phase 1 small molecule active

    1 trial

  34. JSP-CP-012

    Jasper Therapeutics

    allergic asthma

    phase 1 other active

    1 trial

  35. JSP191

    Jasper Therapeutics

    Lower-risk Myelodysplastic Syndrome

    phase 1 small molecule terminated

    1 trial

  36. JSVCT098

    Jiangsu Province Centers for Disease Control and Prevention

    COVID-19

    phase 1 mab completed

    1 trial

  37. JWCAR029 (CD19-targeted Chimeric Antigen Receptor Cells)

    Shanghai University of Traditional Chinese Medicine

    Diffuse Large B Cell Lymphoma

    phase 1 mab completed

    1 trial

  38. JWCAR129

    The First People's Hospital of Lianyungang

    Safety and Efficacy

    phase 1 mab active

    1 trial

  39. JWK002

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    X Linked Retinoschisis

    phase 1 small molecule active

    1 trial

  40. JWK007 Single intravenous infusion administration

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Duchenne Muscular Dystrophy

    phase 1 mab active

    1 trial

  41. JY306 universal NK cell injection

    The First People's Hospital of Lianyungang

    Relapsed or Refractory Hematological Malignancies

    phase 1 mab active

    1 trial

  42. JYEST Cell Injection Infusion

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Prevention of EBV Infection After Allogeneic Hematopoietic Stem Cell Transplantation

    phase 1 mab active

    1 trial

  43. JZP047

    Jazz Pharmaceuticals Ireland Limited

    Healthy Participants

    phase 1 small molecule active

    1 trial

  44. JZP341

    Jazz Pharmaceuticals Ireland Limited

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  45. JZP441

    Jazz Pharmaceuticals Ireland Limited

    Healthy Participants

    phase 1 small molecule completed

    2 trials

  46. JZP441

    Jazz Pharmaceuticals Ireland Limited

    Narcolepsy

    phase 1 small molecule terminated

    1 trial

  47. JZP815

    Jazz Pharmaceuticals Ireland Limited

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  48. JZP898

    Jazz Pharmaceuticals Ireland Limited

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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