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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 49 of 99

  1. Imatinib Mesylate

    Inhibikase Therapeutics

    CML

    phase 1 small molecule completed

    1 trial

  2. Imatinib/Acetaminophen

    Novartis Pharmaceuticals

    Chronic Myeloid Leukemia (CML)

    phase 1 small molecule completed

    1 trial

  3. Impact of CardiolRxTM on Recurrent Pericarditis: An open label Pilot Study

    Cardiol Therapeutics

    Recurrent Pericarditis

    phase 1 other active

    1 trial

  4. Implantation

    Hospital Authority, Hong Kong

    Bone Loss

    phase 1 other active

    1 trial

  5. Improving Peptide Receptor Radionuclide Therapy with PARP inhibitors

    Disc Medicine

    locally advanced or metastatic, well-differentiated gastro-enteropancreatic neuroendocrine tumors.

    phase 1 other active

    1 trial

  6. Inactivated Enterovirus Type 71 Vaccine

    Sinovac Research and Development Co.,

    Infection; Viral, Enterovirus

    phase 1 mab completed

    1 trial

  7. Inactive Marijuana (0% THC)

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Use Disorder

    phase 1 small molecule completed

    1 trial

  8. Incentives for being tobacco free

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Prevention and Cessation

    phase 1 other completed

    1 trial

  9. Indacaterol (QAB149)

    Novartis Pharmaceuticals

    Healthy

    phase 1 small molecule completed

    1 trial

  10. Individualized caffeine cessation instructions

    BRIGHT MINDS BIOSCIENCES INC.

    Self-identified Problematic Caffeine Use

    phase 1 other completed

    1 trial

  11. Infacort

    NEUROCRINE BIOSCIENCES INC

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  12. Infigratinib

    BridgeBio Oncology Therapeutics

    Glioma

    phase 1 small molecule terminated

    1 trial

  13. Infigratinib

    BridgeBio Oncology Therapeutics

    Bladder Transitional Cell Carcinoma

    phase 1 small molecule terminated

    1 trial

  14. Infigratinib

    BridgeBio Oncology Therapeutics

    Breast Cancer

    phase 1 small molecule terminated

    1 trial

  15. Influenza A/California/04/09

    United Therapeutics Europe Ltd

    Influenza A

    phase 1 mab active

    1 trial

  16. Influenza A/Texas/71/2017 (H3N2)

    United Therapeutics Europe Ltd

    Influenza Viral Infections

    phase 1 mab completed

    1 trial

  17. Infudopa i.v.

    Lxo Ireland Designated Activity Company

    Parkinson Disease

    phase 1 small molecule completed

    1 trial

  18. Insulin Lispro

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  19. Insulin Peglispro

    Eli Lilly and Company

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  20. Insulin aspart

    HALOZYME THERAPEUTICS, INC.

    Type 1 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  21. Insulin degludec injection, RD15003

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes

    phase 1 mab completed

    1 trial

  22. Intercerebral implantation of allogenic CD34+ stem cell

    Hospital Authority, Hong Kong

    Ischemic Stroke

    phase 1 other active

    1 trial

  23. Interferon beta-1a

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Subjects

    phase 1 mab completed

    1 trial

  24. Interleukin, NK cells

    Hospital Authority, Hong Kong

    Metastatic Nasopharyngeal

    phase 1 small molecule completed

    1 trial

  25. Interleukin-2

    Iovance Biotherapeutics B.V.

    Chronic Graft Versus Host Disease

    phase 1 small molecule active

    1 trial

  26. Intranasal Oxytocin (IN-OXT)

    Tonix Pharmaceuticals Holding

    Vasopressin Deficiency

    phase 1 small molecule active

    1 trial

  27. Intraparenchymal rAAV1 - (mi)RNA HTT

    Voyager Therapeutics

    Huntington Disease

    phase 1 gene therapy terminated

    1 trial

  28. Intraperitoneal infusion of FAST CEA-targeted CAR-T

    Chongqing Precision Biotech Co., Ltd

    Colorectal Cancer

    phase 1 mab active

    2 trials

  29. Intravenous Artesunate

    United Therapeutics Europe Ltd

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  30. Intravenous Vitamin C

    CNS Pharmaceuticals

    Pancreatic Cancer

    phase 1 small molecule completed

    1 trial

  31. Intravenous stem cell transplantation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stroke

    phase 1 gene therapy active

    1 trial

  32. Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

    Lacuna Pharma Pty Ltd

    Geographic Atrophy

    phase 1 other active

    1 trial

  33. Investigating how NNC0487-0111 regulates insulin in adults with type 2 diabetes

    NovoThirteen

    Type 2 Diabetes

    phase 1 other active

    1 trial

  34. Investigational 13-valent Pneumococcal Polysaccharide Conjugate Vaccine

    Sinovac Research and Development Co.,

    Pneumococcal Infections

    phase 1 mab completed

    1 trial

  35. Investigator-Selected Standard PD-1/PD-L1 Inhibitor-Based Therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Solid Tumors

    phase 1 small molecule active

    1 trial

  36. Invivo CAR-T

    Chongqing Precision Biotech Co., Ltd

    B-Acute Lymphoblastic Leukemia

    phase 1 mab active

    1 trial

  37. Ionis AGT-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  38. Iopofosine I 131

    Cellectar Biosciences

    Breast Cancer

    phase 1 small molecule active

    1 trial

  39. Ipatasertib

    Hoffmann-La Roche

    Breast Cancer

    phase 1 small molecule terminated

    1 trial

  40. Ipilimumab

    Regeneron UK Limited

    Stage III Prostate Cancer

    phase 1 mab terminated

    1 trial

  41. Ipilimumab

    VACCINEX, INC.

    Pathologic Stage IIIB Cutaneous Melanoma AJCC v8

    phase 1 mab active

    1 trial

  42. Irinotecan Accord 20 mg/ml concentraat voor oplossing voor infusie

    Disc Medicine

    Gastric cancer

    phase 1 small molecule active

    1 trial

  43. Irinotecan liposome II combination therapy regimen

    Chongqing Claruvis Pharmaceutical Co.,

    Non-Muscle Invasive Bladder Urothelial Carcinoma

    phase 1 small molecule active

    1 trial

  44. Isradipine

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 1 small molecule completed

    1 trial

  45. Itacitinib

    Incyte

    Acute Graft-versus-host Disease

    phase 1 small molecule completed

    1 trial

  46. Itepekimab AI

    Regeneron UK Limited

    Chronic Obstructive Pulmonary Disease

    phase 1 small molecule completed

    1 trial

  47. Itraconazole

    United Therapeutics Europe Ltd

    Non-small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  48. Itraconazole

    COGNITION THERAPEUTICS INC

    Drug Interaction

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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