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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 46 of 99

  1. Hydrocodone Bitartrate extended-release tablet

    Teva Pharma GmbH

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  2. Hydrocodone bitartrate extended-release tablet

    Teva Pharma GmbH

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  3. Hydrocortisone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule active

    1 trial

  4. Hydrocortisone granules

    NEUROCRINE BIOSCIENCES INC

    Adrenal Insufficiency

    phase 1 small molecule completed

    1 trial

  5. Hydromorphone

    Grace Therapeutics

    Pain

    phase 1 small molecule completed

    1 trial

  6. Hydromorphone 16 mg

    Janssen Cilag International NV

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  7. Hydronidone capsules

    The First People's Hospital of Lianyungang

    Liver Fibrosis

    phase 1 small molecule active

    1 trial

  8. Hyperpolarized xenon

    United Therapeutics Europe Ltd

    Lung Disease

    phase 1 small molecule completed

    1 trial

  9. I-131-CLR1404

    Cellectar Biosciences

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  10. I-131-CLR1404

    Cellectar Biosciences

    Cancer

    phase 1 small molecule completed

    1 trial

  11. I-131-CLR1404

    Cellectar Biosciences

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  12. I124-NM404

    Cellectar Biosciences

    Non Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  13. I3Y-MC-JPCE

    Eli Lilly Co.

    Lung Cancer or Breast Cancer

    phase 1 other active

    1 trial

  14. I3Y-MC-JPEI

    Eli Lilly Co.

    Prostatic Neoplasms

    phase 1 other active

    1 trial

  15. I8H-MC-BDDG

    Eli Lilly Co.

    Type 2 Diabetes Mellitus

    phase 1 other active

    1 trial

  16. IASO104

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed/Refractory Multiple Myeloma (RRMM)

    phase 1 mab active

    1 trial

  17. IASO206 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed/Refractory Multiple Myeloma (RRMM)

    phase 1 small molecule active

    1 trial

  18. IASO206 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 mab active

    1 trial

  19. IBR733 Cell Injection

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial

  20. IC 2018-06

    The George Institute

    Patients with recurrent and/or metastatic solid cancer.

    phase 1 other active

    1 trial

  21. IC 2022-10

    The George Institute

    Patients with pretreated, metastatic or locally advanced cancer for the dose escalation part and dose expansion cohorts in patients with advanced triple-negative breast cancers and advanced cancers with ATM mutation.

    phase 1 other active

    1 trial

  22. ICG-Cisplatin Nanoprobe (NIR-II NanoM)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Liver Cancer, Adult

    phase 1 small molecule active

    1 trial

  23. ICI201

    The First People's Hospital of Lianyungang

    Relapsed/Refractory Multiple Myeloma

    phase 1 small molecule terminated

    1 trial

  24. ICO-2023-16

    CERO THERAPEUTICS HOLDINGS, INC.

    cell lung carcinoma

    phase 1 other active

    1 trial

  25. ICO-2023-25 OPTIMISE

    CERO THERAPEUTICS HOLDINGS, INC.

    metastatic prostate cancer

    phase 1 other active

    1 trial

  26. ICT-121 DC vaccine

    Chongqing Precision Biotech Co., Ltd

    Glioblastoma Multiforme

    phase 1 mab completed

    1 trial

  27. ID-064-108

    Viatris Pharmaceuticals Co.,

    Not applicable - healthy volunteer trial

    phase 1 other active

    1 trial

  28. ID-080-111

    Lacuna Pharma Pty Ltd

    Not applicable - healthy volunteer trial

    phase 1 other active

    1 trial

  29. ID-090-101

    Lacuna Pharma Pty Ltd

    Clostridioides difficile (C. difficile)

    phase 1 other active

    1 trial

  30. ID-LV305

    Lxo Ireland Designated Activity Company

    Melanoma - Currently Enrolling

    phase 1 mab completed

    1 trial

  31. IDC-G305

    Lxo Ireland Designated Activity Company

    Melanoma

    phase 1 mab completed

    1 trial

  32. IDE-161

    IDEAYA Biosciences

    Advanced or Metastatic Solid Tumors

    phase 1 small molecule active

    1 trial

  33. IDE034

    IDEAYA Biosciences

    Esophageal Squamous Cell Carcinoma

    phase 1 small molecule active

    1 trial

  34. IDE397

    IDEAYA Biosciences

    Solid Tumor

    phase 1 small molecule active

    1 trial

  35. IDE397-001

    IDEAYA Biosciences

    Advanced Solid Tumors

    phase 1 other active

    1 trial

  36. IDE892

    IDEAYA Biosciences

    NSCLC Adenocarcinoma

    phase 1 small molecule active

    1 trial

  37. IFx-Hu2.0

    TuHURA Biosciences, Inc./NV

    Cutaneous Squamous Cell Carcinoma

    phase 1 mab completed

    1 trial

  38. IFx-Hu2.0

    TuHURA Biosciences, Inc./NV

    Merkel Cell Carcinoma

    phase 1 mab completed

    1 trial

  39. IFx-Hu2.0

    TuHURA Biosciences, Inc./NV

    Cutaneous Melanoma, Stage III

    phase 1 mab completed

    1 trial

  40. IIT2025079

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    AML - Acute Myeloid Leukemia

    phase 1 mab active

    1 trial

  41. IL-2

    Alaunos Therapeutics

    Lymphoma

    phase 1 small molecule completed

    1 trial

  42. IL-22BP mRNA vaccine injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Refractory Malignant Solid Tumors

    phase 1 mab active

    1 trial

  43. IM034-1000

    Bristol-Myers Squibb Australia Pty Ltd

    Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus, Systemic Lupus Erythematosus

    phase 1 other active

    1 trial

  44. IM060-0001

    Bristol-Myers Squibb Australia Pty Ltd

    Systemic Sclerosis, Idiopathic Inflammatory Myopathy, Rheumatoid Arthritis, Systemic Lupus Erythematosus

    phase 1 other active

    1 trial

  45. IMATI-10-25

    Lacuna Pharma Pty Ltd

    Acute Lymphoblastic Leukemia (Ph+ ALL), (Ph+) Chronic Myeloid Leukemia

    phase 1 other active

    1 trial

  46. IMC-I109V Single Ascending Dose

    Immunocore Ireland Limited

    Hepatitis B, Chronic

    phase 1 small molecule terminated

    1 trial

  47. IMM-BCP-01

    United Therapeutics Europe Ltd

    SARS-CoV2 Infection

    phase 1 small molecule terminated

    1 trial

  48. IMP3-saRNA (YMN-136) Vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Small Cell Lung Cancer

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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