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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 43 of 99

  1. GMX1777

    Teva Pharma GmbH

    Solid Tumors and Lymphomas

    phase 1 small molecule terminated

    1 trial

  2. GPC3 and/or TGFβ targeting CAR-T cells

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma

    phase 1 mab active

    1 trial

  3. GPC3-CAR-T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma

    phase 1 mab on hold

    1 trial

  4. GPRC5D CAR-T cell intravenous infusion

    The First People's Hospital of Lianyungang

    Plasma Cell Dyscrasias

    phase 1 mab active

    1 trial

  5. GR-MD-02

    GALECTIN THERAPEUTICS INC

    Non-Alcoholic Steatohepatitis (NASH)

    phase 1 small molecule completed

    1 trial

  6. GR-MD-02

    GALECTIN THERAPEUTICS INC

    Melanoma

    phase 1 small molecule completed

    1 trial

  7. GRNOPC1

    Lineage Cell Therapeutics

    Spinal Cord Injury

    phase 1 mab completed

    1 trial

  8. GRT-1C101

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 other active

    1 trial

  9. GRT-1C102

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 other active

    1 trial

  10. GRoningen Early-PD Ambroxol Treatment Pharmacokinetics

    Disc Medicine

    Parkinson's disease

    phase 1 other active

    1 trial

  11. GS-0272

    Gilead Sciences Ireland UC

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial

  12. GS-2829

    Gilead Sciences Ireland UC

    Chronic Hepatitis B

    phase 1 mab completed

    1 trial

  13. GS-5245 tablets 175 mg, GS-5245 tablets 350 mg

    Gilead Sciences Pty Limited

    Renal Impairment

    phase 1 small molecule active

    1 trial

  14. GSBR-1290

    Structure Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  15. GSBR-1290 (Capsule/Tablet)

    Structure Therapeutics

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  16. GSBR-1290-07

    Structure Therapeutics

    Not applicable - Healthy volonteers

    phase 1 other active

    1 trial

  17. GSK2269557 ELLIPTA DPI

    GlaxoSmithKline

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    1 trial

  18. GSK2879552

    GlaxoSmithKline

    Leukaemia, Myelocytic, Acute

    phase 1 small molecule terminated

    1 trial

  19. GSK525762

    GlaxoSmithKline

    Solid Tumours

    phase 1 small molecule terminated

    1 trial

  20. GSK5533524

    GlaxoSmithKline

    Neoplasms

    phase 1 small molecule active

    1 trial

  21. GSK961081

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    2 trials

  22. GSK961081 15mcg SD

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    1 trial

  23. GST-HG121 tablets

    Jian Li

    Pharmacokinetics

    phase 1 small molecule active

    1 trial

  24. GST-HG121 tablets

    The First People's Hospital of Lianyungang

    Pharmacokinetics

    phase 1 small molecule active

    1 trial

  25. GT-02287

    Gain Therapeutics

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  26. GTB-5550

    GT Biopharma

    Tri-specific Killer Engager

    phase 1 small molecule active

    1 trial

  27. GTX-101

    Grace Therapeutics

    Postherpetic Neuralgia

    phase 1 small molecule active

    1 trial

  28. GTX-102 medium dose fast Period 1 and Period 2

    Grace Therapeutics

    Ataxia Telangiectasia

    phase 1 small molecule active

    1 trial

  29. GTX-104

    Grace Therapeutics

    Aneurysmal Subarachnoid Hemorrhage

    phase 1 small molecule completed

    1 trial

  30. GV20-0251

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HCC - Hepatocellular Carcinoma

    phase 1 small molecule active

    1 trial

  31. GX15-070MS

    Teva Pharma GmbH

    Chronic Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  32. GZ17-6.02

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  33. GZR33-T1D-US101

    Lacuna Pharma Pty Ltd

    Type 1 diabetes Mellitus

    phase 1 other active

    1 trial

  34. Ga68-Dolacga Injection

    Taiwan Liposome Company

    Safety Issues

    phase 1 small molecule completed

    1 trial

  35. Galidesivir

    Biocryst

    COVID-19

    phase 1 small molecule terminated

    1 trial

  36. Gallium-68 NODAGA-JR11

    The First People's Hospital of Lianyungang

    Neuroendocrine Tumors

    phase 1 small molecule active

    1 trial

  37. Gallium-68 citrate

    United Therapeutics Europe Ltd

    Prostatic Neoplasms

    phase 1 small molecule completed

    1 trial

  38. Garetosmab

    Regeneron UK Limited

    Obesity

    phase 1 small molecule terminated

    1 trial

  39. Gemtuzumab Ozogamicin

    Jazz Pharmaceuticals Ireland Limited

    Acute Myelogenous Leukemia

    phase 1 small molecule terminated

    1 trial

  40. Gilteritinib

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia With FLT3/ITD Mutation

    phase 1 small molecule active

    1 trial

  41. Givosiran

    Alnylam Netherlands B.V.

    Acute Intermittent Porphyria (AIP)

    phase 1 small molecule completed

    1 trial

  42. Glimepiride 4 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  43. Glucagon

    United Therapeutics Europe Ltd

    Type 1 Diabetes Mellitus With Hypoglycemia

    phase 1 small molecule completed

    1 trial

  44. Glucophage® XR 750 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  45. Glucose

    United Therapeutics Europe Ltd

    Diabetes Mellitus

    phase 1 other completed

    1 trial

  46. Glyburide

    United Therapeutics Europe Ltd

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  47. Glyburide/Metformin 5 mg/500 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  48. Glycerol Phenylbutyrate 1100 MG/ML [Ravicti]

    S.L

    STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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