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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 38 of 99

  1. Entinostat

    Syndax Pharmaceuticals

    Drug Interaction

    phase 1 small molecule completed

    1 trial

  2. Enzalutamide

    CORCEPT THERAPEUTICS INC

    Prostate Cancer

    phase 1 small molecule completed

    1 trial

  3. Epetraborole

    AN2 Therapeutics

    Renal Insufficiency

    phase 1 small molecule completed

    1 trial

  4. Epetraborole

    AN2 Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  5. Epetraborole and matching placebo

    AN2 Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  6. Epidiolex

    BRIGHT MINDS BIOSCIENCES INC.

    CBD

    phase 1 small molecule active

    1 trial

  7. Epidiolex 100 mg/mL Oral Solution

    Jazz Pharmaceuticals Ireland Limited

    Electrical Status Epilepticus of Slow-Wave Sleep

    phase 1 small molecule completed

    1 trial

  8. Eplontersen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  9. Eprolidone

    The First People's Hospital of Lianyungang

    Chronic Heart Failure Patients

    phase 1 small molecule active

    1 trial

  10. Erwinase

    Jazz Pharmaceuticals Ireland Limited

    Acute Lymphoblastic Leukemia

    phase 1 small molecule completed

    1 trial

  11. Erwinia Chrysanthemi asparaginase

    Jazz Pharmaceuticals Ireland Limited

    Acute Lymphoblastic Leukemia (ALL)

    phase 1 small molecule terminated

    1 trial

  12. EryDex (dexamethasone sodium phosphate encapsulated erythrocytes)

    Quince Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  13. Erythromycin lactobionate

    ADIAL PHARMACEUTICALS, INC.

    Diabetes Mellitus, Type 1

    phase 1 small molecule completed

    1 trial

  14. Escitalopram

    Universal Integrated

    Major Depressive Disorder

    phase 1 small molecule completed

    1 trial

  15. Esketamine injection group (0.25 mg/kg)

    The First People's Hospital of Lianyungang

    Esketamine

    phase 1 small molecule active

    1 trial

  16. Esomeprazole Capsule

    Takeda

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  17. Estradiol/Norethindrone acetate

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  18. Etanercept

    United Therapeutics Europe Ltd

    Gulf War Illness

    phase 1 small molecule active

    1 trial

  19. Ethinyl Estradioll/Levonorgestrel (EE/LNG)

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  20. Etrasimod Arginine Blue

    Pfizer Australia Pty Ltd

    Ulcerative Colitis and immune-mediated inflammatory disorders

    phase 1 small molecule active

    1 trial

  21. Etripamil Nasal Spray 70mg

    Milestone Pharmaceuticals

    Healthy Chinese Subjects

    phase 1 small molecule completed

    1 trial

  22. Etrumadenant

    Arcus Biosciences

    Non-small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  23. Etrumadenant

    Arcus Biosciences

    Healthy Participants

    phase 1 small molecule completed

    2 trials

  24. Etrumadenant

    Arcus Biosciences

    TNBC - Triple-Negative Breast Cancer

    phase 1 small molecule completed

    1 trial

  25. Etrumadenant

    Arcus Biosciences

    Non Small Cell Lung Cancer Metastatic

    phase 1 small molecule completed

    1 trial

  26. Evaluate the effects of Environmental Enrichment (EE) on alcohol consumption

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol Use Disorder

    phase 1 other active

    1 trial

  27. Evaluation of AG-181 in Subjects 18 to 69 Years of Age With Phenylketonuria

    Lacuna Pharma Pty Ltd

    Phenylketonuria

    phase 1 other active

    1 trial

  28. Evaluation of bioequivalence of two products...

    Lacuna Pharma Pty Ltd

    No therapeutic indication in the current trial with healthy volunteers.

    phase 1 other active

    1 trial

  29. Evaluation of the Novel Therapeutic Hepatitis... for chronic Hepatitis B

    Disc Medicine

    chronic Hepatitis B

    phase 1 other active

    1 trial

  30. Evinacumab

    Regeneron UK Limited

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  31. Evixapodlin

    Gilead Sciences Ireland UC

    Advanced Solid Tumors

    phase 1 small molecule terminated

    1 trial

  32. Evolocumab

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Subjects

    phase 1 mab completed

    1 trial

  33. Evorpacept

    ALX ONCOLOGY HOLDINGS INC

    Bladder Cancer

    phase 1 small molecule completed

    1 trial

  34. Evorpacept (ALX148)

    ALX ONCOLOGY HOLDINGS INC

    Metastatic Cancer

    phase 1 small molecule completed

    1 trial

  35. Ex-vivo expanded allogeneic γδ T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    AML (Acute Myelogenous Leukemia)

    phase 1 mab active

    1 trial

  36. Ex-vivo expanded allogeneic γδT cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Hodgkin's Lymphoma (NHL)

    phase 1 mab active

    1 trial

  37. Exenatide Circular RNA-Lipid Nanoparticle Injection（ CR059））

    The First People's Hospital of Lianyungang

    T2DM

    phase 1 small molecule active

    1 trial

  38. Exparel Injectable Product

    Pacira Ireland Limited

    Bunion

    phase 1 small molecule completed

    1 trial

  39. Exparel Injectable Product

    Pacira Ireland Limited

    Breast Augmentation

    phase 1 small molecule completed

    1 trial

  40. Experimental Vaccine 1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    COVID-19 Pneumonia

    phase 1 mab completed

    1 trial

  41. Exposure to sporting events

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Coronary Heart Disease

    phase 1 other completed

    1 trial

  42. External non-invasive stimulation

    United Therapeutics Europe Ltd

    TBI (Traumatic Brain Injury)

    phase 1 other active

    1 trial

  43. Extracellular Vesicles from Mesenchymal Stem Cells

    Regeneron Ireland Designated Activity Company (DAC)

    COVID-19 Pneumonia

    phase 1 mab active

    1 trial

  44. Extraluminal use of Univent bronchial Blocker

    Hospital Authority, Hong Kong

    Therapeutic Procedural Complication

    phase 1 other completed

    1 trial

  45. EyeD-010-003

    Lacuna Pharma Pty Ltd

    Glaucoma

    phase 1 other active

    1 trial

  46. F2F

    BRIGHT MINDS BIOSCIENCES INC.

    Prescription Stimulant Misuse

    phase 1 other active

    1 trial

  47. FATE-NK100

    Zafatek

    HER2 Positive Gastric Cancer

    phase 1 small molecule completed

    1 trial

  48. FAVICOVIR 200 mg Film Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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