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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 37 of 99

  1. ENZAL-15-24

    Lacuna Pharma Pty Ltd

    Prostate cancer

    phase 1 other active

    1 trial

  2. ENZAL-16-24

    Lacuna Pharma Pty Ltd

    Prostate cancer

    phase 1 other active

    1 trial

  3. EP-104IAR

    EUPRAXIA PHARMACEUTICALS INC.

    Osteoarthritis, Knee

    phase 1 small molecule completed

    1 trial

  4. EP-262-102

    Lacuna Pharma Pty Ltd

    Chronic Inducible Urticaria

    phase 1 other active

    1 trial

  5. EP395-006

    Lacuna Pharma Pty Ltd

    Healthy volunteers [targeted indication: chronic obstructive pulmonary disease (COPD)]

    phase 1 other active

    1 trial

  6. EPIN-IJS-1002

    Mylan Pharma UK

    Allergic reactions (Type 1), including anaphylaxis, idiopathic anaphylaxis or exercise-induced anaphylaxis

    phase 1 other active

    1 trial

  7. ES414

    Aptevo Therapeutics

    Prostate Cancer

    phase 1 mab completed

    1 trial

  8. ESAT6-CFP10

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 mab completed

    1 trial

  9. ESN364

    Astellas Pharma Inc

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  10. ET1402L1-ARTEMIS™ T cells -IV

    AEON Biopharma

    Hepatocellular Carcinoma

    phase 1 mab completed

    1 trial

  11. ETC-1002

    Esperion Therapeutics

    Safety Evaluation of Escalating Doses

    phase 1 small molecule completed

    1 trial

  12. ETC-1002 or placebo

    Esperion Therapeutics

    Mild Dyslipidemia

    phase 1 small molecule completed

    1 trial

  13. ETC-159

    BRIGHT MINDS BIOSCIENCES INC.

    With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer

    phase 1 small molecule active

    1 trial

  14. ETC-1907206

    BRIGHT MINDS BIOSCIENCES INC.

    Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)

    phase 1 small molecule terminated

    1 trial

  15. ETC-1922159

    BRIGHT MINDS BIOSCIENCES INC.

    Solid Tumors

    phase 1 small molecule active

    1 trial

  16. ETH-155008

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NHL, Adult

    phase 1 small molecule active

    1 trial

  17. ETH-155008

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NHL

    phase 1 small molecule terminated

    1 trial

  18. EVM16

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced or Recurrent Solid Tumors

    phase 1 mab active

    1 trial

  19. EVOLVE104

    United Therapeutics Europe Ltd

    Bladder Cancer

    phase 1 small molecule active

    1 trial

  20. EVT801

    KAZIA THERAPEUTICS LTD

    Solid Tumor, Adult

    phase 1 small molecule completed

    1 trial

  21. EWO-ISO-2024/BE2

    Lacuna Pharma Pty Ltd

    not applicable (submitted trial is a bioequivalence study)

    phase 1 other active

    1 trial

  22. EXPAREL

    Pacira Ireland Limited

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  23. EXPAREL

    Pacira Ireland Limited

    Spinal Fusion

    phase 1 small molecule completed

    1 trial

  24. EXPAREL

    Pacira Ireland Limited

    Healthy

    phase 1 small molecule terminated

    1 trial

  25. EXS73565

    RECURSION PHARMACEUTICALS, INC.

    Relapsed or Refractory B-cell Malignancies

    phase 1 small molecule active

    1 trial

  26. EXS74539

    RECURSION PHARMACEUTICALS, INC.

    Solid Tumor

    phase 1 small molecule active

    1 trial

  27. EXT608

    Universal Integrated

    Safety Issues

    phase 1 small molecule completed

    1 trial

  28. EYP001-110/OP1147

    Lacuna Pharma Pty Ltd

    Healthy volunteers, Impaired renal function and suspected MASH

    phase 1 other active

    1 trial

  29. Ebola Vaccine - low dose

    United Therapeutics Europe Ltd

    Ebola Virus Disease

    phase 1 mab completed

    1 trial

  30. Effect of NBI-921355 on corticospinal excitability in healthy participants

    NEUROCRINE BIOSCIENCES INC

    Epilepsy

    phase 1 other active

    1 trial

  31. Effect of Renal Impairment on Enpatoran Pharmacokinetics

    Merck Sharp and Dohme

    Healthy volunteers and patients with renal impairment; Intended indication: autoimmune diseases; systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE), as well as dermatomyositis (DM) and polymyositis (PM).

    phase 1 other active

    1 trial

  32. Efficacy of LCAR-T2C CAR-T cells

    Nanjing Legend Biotech Co.

    T Cell Lymphoma

    phase 1 small molecule terminated

    1 trial

  33. Efficacy of LCAR-T2C CAR-T cells

    Nanjing Legend Biotech Co.

    CD4+ T Lymphocyte Tumor (T Cell Lymphoma and T Cell Leukemia)

    phase 1 small molecule terminated

    1 trial

  34. Elagolix

    NEUROCRINE BIOSCIENCES INC

    Folliculogenesis

    phase 1 small molecule completed

    1 trial

  35. Electroporation-Mediated Plasmid DNA Vaccine Therapy

    INOVIO PHARMACEUTICALS, INC.

    Chronic Hepatitis

    phase 1 mab active

    1 trial

  36. Elimusertib (BAY1895344)

    Bayer HealthCare AG

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  37. Eltanexor

    Karyopharm Therapeutics Inc

    Relapsed Myelodysplastic Syndrome

    phase 1 small molecule active

    1 trial

  38. Empagliflozin 10 MG Oral Tablet [Jardiance]

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  39. Emtricitabine

    United Therapeutics Europe Ltd

    HIV

    phase 1 small molecule completed

    1 trial

  40. Encapsulated Calcium

    United Therapeutics Europe Ltd

    Pregnancy

    phase 1 other completed

    1 trial

  41. Endo Tool

    United Therapeutics Europe Ltd

    Burns

    phase 1 other completed

    1 trial

  42. Engineered mitochondrial vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Solid Tumor Malignancies

    phase 1 mab active

    1 trial

  43. Entinostat

    Syndax Pharmaceuticals

    Volunteers

    phase 1 small molecule completed

    2 trials

  44. Entinostat

    Syndax Pharmaceuticals

    Fallopian Tube Cancer

    phase 1 small molecule terminated

    1 trial

  45. Entinostat

    Syndax Pharmaceuticals

    Drug Interaction

    phase 1 small molecule completed

    1 trial

  46. Entinostat

    Syndax Pharmaceuticals

    Neoplasms

    phase 1 small molecule completed

    2 trials

  47. Entinostat

    Syndax Pharmaceuticals

    Pancreas Cancer

    phase 1 small molecule terminated

    1 trial

  48. Entinostat

    Syndax Pharmaceuticals

    Metastatic Breast Cancer

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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