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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 35 of 99

  1. Dexlansoprazole MR

    Takeda

    Gastroesophageal Reflux

    phase 1 small molecule completed

    1 trial

  2. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Cesarean Section, Affecting Fetus or Newborn

    phase 1 small molecule completed

    1 trial

  3. Dexmedetomidine

    The First People's Hospital of Lianyungang

    Heart Injuries

    phase 1 small molecule active

    1 trial

  4. Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg

    BioXcel Therapeutics

    Alcohol Use Disorder (AUD)

    phase 1 small molecule active

    1 trial

  5. Dexmethylphenidate Hydrochloride

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  6. Dextromethorphan HBr

    Galera Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  7. Digoxin

    Takeda

    Cytomegalovirus (CMV)

    phase 1 small molecule completed

    1 trial

  8. Digoxin

    PUMA BIOTECHNOLOGY, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  9. Digoxin

    Hospital Authority, Hong Kong

    Healthy

    phase 1 small molecule completed

    1 trial

  10. Digoxin

    The First People's Hospital of Lianyungang

    Healthy

    phase 1 small molecule completed

    1 trial

  11. Digoxin vs Digoxin + BEM/RZR vs Digoxin + 2h BEM/RZR

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  12. Dihydrexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule active

    1 trial

  13. Dinutuximab

    United Therapeutics Europe Ltd

    Neuroblastoma

    phase 1 small molecule active

    2 trials

  14. Disulfiram

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 1 small molecule completed

    1 trial

  15. Divalproex Sodium

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    4 trials

  16. Divalproex Sodium Extended-release 250mg

    BRIGHT MINDS BIOSCIENCES INC.

    Epilepsy

    phase 1 small molecule active

    1 trial

  17. Docetaxel

    Mereo BioPharma Group plc

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  18. Docetaxel

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 small molecule completed

    1 trial

  19. Dociparstat sodium

    BRIGHT MINDS BIOSCIENCES INC.

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  20. Dofetilide

    BRIGHT MINDS BIOSCIENCES INC.

    Drug-induced QT Prolongation

    phase 1 small molecule completed

    1 trial

  21. Domvanalimab

    Arcus Biosciences

    Solid Tumor, Unspecified, Adult

    phase 1 small molecule completed

    1 trial

  22. Donepezil

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  23. Donepezil Dihydroxynaphthalate for Injection

    Shanghai University of Traditional Chinese Medicine

    Alzheimer Disease

    phase 1 small molecule active

    1 trial

  24. Donepezil Hydrochloride

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  25. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Diffuse Intrinsic Pontine Glioma

    phase 1 small molecule terminated

    1 trial

  26. Dose dense re-challenge of high dose methotre...

    Pari Pharma GmbH

    Oncology: RELAPSED PRIMARY CNS LYMPHOMA

    phase 1 other active

    1 trial

  27. Dose escalation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Poor Graft Function

    phase 1 mab active

    1 trial

  28. Dose escalation of SA030

    Suzhou Ribo Life Science Co.

    Obese

    phase 1 small molecule active

    1 trial

  29. Dose escalation trial of BNT152+153 in patients with cancer

    BioNTech SE

    Various solid tumors that are metastatic or unresectable

    phase 1 other active

    1 trial

  30. Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor

    Takeda

    Alpha 1-Antitrypsin Deficiency

    phase 1 mab completed

    1 trial

  31. Doxorubicin

    United Therapeutics Europe Ltd

    Pancreatic Ductal Adenocarcinoma

    phase 1 small molecule terminated

    1 trial

  32. Doxycycline Monohydrate

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  33. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Bipolar Disorder

    phase 1 small molecule terminated

    1 trial

  34. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  35. Dronabinol Capsules

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 1 small molecule active

    1 trial

  36. Drospirenone/Ethinyl Estradiol (Gianvi®)

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  37. Drug 601

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Wet Age-related Macular Degeneration

    phase 1 small molecule active

    1 trial

  38. Drug 601

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Diabetic Macular Edema

    phase 1 small molecule active

    1 trial

  39. Drug A (Blinded Drug)

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule on hold

    1 trial

  40. Drug Product De-TIL-0255

    Nurix Therapeutics

    Platinum-resistant Ovarian Cancer

    phase 1 mab terminated

    1 trial

  41. Drug-AZD8931

    AstraZeneca

    Breast Neoplasm

    phase 1 small molecule terminated

    1 trial

  42. Drug: AT-527 + rosuvastatin

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  43. Drug: BG-T187

    BEONE MEDICINES AUS PTY LTD

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  44. Drugs administration

    Hospital Authority, Hong Kong

    Rotator Cuff Tears of the Shoulder

    phase 1 small molecule active

    1 trial

  45. Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy

    Nanjing Legend Biotech Co.

    Refractory B Acute Lymphoblastic Leukemia

    phase 1 small molecule terminated

    1 trial

  46. Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy

    Nanjing Legend Biotech Co.

    Lymphoma, B-Cell

    phase 1 small molecule terminated

    1 trial

  47. Dual-Wavelength Quantitative Fluorescence End... for Esophageal cancer

    Disc Medicine

    Esophageal cancer

    phase 1 other active

    1 trial

  48. Dupilumab

    Regeneron UK Limited

    Atopic Disorders

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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