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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 34 of 99

  1. Danavorexton

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  2. Danicopan

    Alexion Europe SAS

    Healthy

    phase 1 small molecule completed

    1 trial

  3. Daprodustat 2 mg tablet

    GlaxoSmithKline

    Anaemia

    phase 1 small molecule completed

    1 trial

  4. Daratumumab

    Takeda

    Newly Diagnosed Primary Amyloidosis

    phase 1 mab active

    1 trial

  5. Daratumumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Aplastic Anemia

    phase 1 small molecule completed

    1 trial

  6. Daridorexant

    Jian Li

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  7. Darlifarnib

    Kura Oncology

    Solid Tumors With HRAS Alterations

    phase 1 small molecule active

    1 trial

  8. Dasatinib

    United Therapeutics Europe Ltd

    Malignant Pleural Mesothelioma

    phase 1 small molecule completed

    1 trial

  9. Dasatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed AML

    phase 1 small molecule terminated

    1 trial

  10. Daunorubicin

    Protara Therapeutics

    Acute Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  11. Dazucorilant

    CORCEPT THERAPEUTICS INC

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  12. Dazucorilant

    CORCEPT THERAPEUTICS INC

    Healthy Adults

    phase 1 small molecule completed

    1 trial

  13. Debio 0123-102

    Alphapharm Pty Ltd

    Arm A: Diagnosed with uterine serous carcinoma (USC) Arm B: Diagnosed with recurrent or progressive, high-grade epithelial ovarian cancer (EOC) with cyclin E1-driven selection Arm C: Diagnosed with solid tumor with biomarker-driven selection

    phase 1 other active

    1 trial

  14. Debio 0123-106

    Alphapharm Pty Ltd

    Advanced solid tumors with CCNE1 amplification or deleterious mutations in FBXW7 or other proprietary gene

    phase 1 small molecule active

    1 trial

  15. Debio 0123-SCLC-104

    Alphapharm Pty Ltd

    Small cell lung cancer

    phase 1 other active

    1 trial

  16. Debio 1453-101

    Alphapharm Pty Ltd

    Sexual Transmitted Infection (STI)

    phase 1 other active

    1 trial

  17. Debio0123-101

    Alphapharm Pty Ltd

    Patients with tumors

    phase 1 other active

    1 trial

  18. Decision Aid

    United Therapeutics Europe Ltd

    Chronic Kidney Failure

    phase 1 other completed

    1 trial

  19. Decitabine

    Foghorn Therapeutics

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  20. Deferitazole (disodium salt, granule)

    Takeda

    Healthy

    phase 1 small molecule terminated

    1 trial

  21. Defibrotide

    Jazz Pharmaceuticals Ireland Limited

    COVID

    phase 1 small molecule completed

    1 trial

  22. Deflazacort

    PTC THERAPEUTICS, INC.

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  23. Deflazacort

    PTC THERAPEUTICS, INC.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  24. Deflazacort

    PTC THERAPEUTICS, INC.

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  25. Deflazacort and rifampin

    PTC THERAPEUTICS, INC.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  26. Delayed Release 6 mercaptopurine

    Teva Pharma GmbH

    Crohns Disease

    phase 1 small molecule completed

    1 trial

  27. Delta-9-THC Low Dose

    BRIGHT MINDS BIOSCIENCES INC.

    Age-related Cognitive Decline

    phase 1 small molecule active

    1 trial

  28. Demcizumab

    Mereo BioPharma Group plc

    Primary Peritoneal Carcinoma

    phase 1 small molecule terminated

    1 trial

  29. Demcizumab

    Mereo BioPharma Group plc

    Non Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  30. Demcizumab

    Mereo BioPharma Group plc

    Locally Advanced or Metastatic Solid Tumors

    phase 1 small molecule completed

    1 trial

  31. Dendritic Cell (DC1) Vaccine

    VACCINEX, INC.

    HER2-positive Breast Cancer

    phase 1 mab active

    1 trial

  32. Dendritic Cell Vaccination

    Quantum Biopharma

    Metastatic Breast Cancer

    phase 1 mab active

    1 trial

  33. Dendritic Cell Vaccine

    United Therapeutics Europe Ltd

    Leptomeningeal Disease

    phase 1 mab active

    1 trial

  34. Dendritic cell therapy combined with surgery in mesothelioma (ENSURE)

    Disc Medicine

    Adult patients diagnosed with resectable epithelioid MPM, following first-line chemotherapy.

    phase 1 other active

    1 trial

  35. Denifanstat

    Sagimet Biosciences

    Healthy

    phase 1 small molecule completed

    1 trial

  36. DepoDur (extended-release epidural morphine)

    Pacira Ireland Limited

    Postoperative Pain

    phase 1 small molecule completed

    1 trial

  37. Descartes 30

    Cartesian Therapeutics

    Acute Respiratory Distress Syndrome

    phase 1 mab terminated

    1 trial

  38. Descartes-08

    Cartesian Therapeutics

    Multiple Myeloma

    phase 1 mab terminated

    1 trial

  39. Descartes-15

    Cartesian Therapeutics

    Refractory Multiple Myeloma

    phase 1 small molecule terminated

    1 trial

  40. Descartes-25

    Cartesian Therapeutics

    Multiple Myeloma

    phase 1 small molecule terminated

    1 trial

  41. Desmopressin Acetate 0.2 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  42. Desogestrel/ethinyl estradiol and ethinyl estradiol

    Teva Pharma GmbH

    Follicle Development

    phase 1 small molecule completed

    1 trial

  43. Dexamethasone

    NEUROCRINE BIOSCIENCES INC

    Healthy

    phase 1 small molecule completed

    1 trial

  44. Dexlansoprazole

    Takeda

    Pediatric Gastroesophageal Reflux Disease

    phase 1 small molecule terminated

    1 trial

  45. Dexlansoprazole

    Takeda

    Homeostasis

    phase 1 small molecule completed

    1 trial

  46. Dexlansoprazole

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  47. Dexlansoprazole Delayed Release Orally Disintegrating Tablets

    Takeda

    Bioavailability

    phase 1 small molecule completed

    1 trial

  48. Dexlansoprazole Injection

    The First People's Hospital of Lianyungang

    Effect of Drugs

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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