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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 32 of 99

  1. Cypep-1

    BRIGHT MINDS BIOSCIENCES INC.

    Cutaneous Warts

    phase 1 small molecule completed

    1 trial

  2. D-FR-60010-015

    Ipsen

    Metastatic Pancreatic Adenocarcinoma

    phase 1 other active

    1 trial

  3. D/ChAd63-CA

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  4. D0816C00025

    AstraZeneca AB

    solid tumors

    phase 1 small molecule active

    1 trial

  5. D1346C00015

    AstraZeneca AB

    Neurofibromatosis Type 1 (NF1) Related Plexiform Neurofibromas (PN)

    phase 1 small molecule active

    1 trial

  6. D1ME100 (dengue-1 premembrane/envelope DNA vaccine)

    United Therapeutics Europe Ltd

    Dengue

    phase 1 mab completed

    1 trial

  7. D3560C00817

    AstraZeneca AB

    Clinical trial healthy volunteer

    phase 1 other active

    1 trial

  8. D3615C00005

    AstraZeneca AB

    Healthy participants

    phase 1 other active

    1 trial

  9. D5084C00016

    AstraZeneca AB

    Healthy Volunteers

    phase 1 other active

    1 trial

  10. D533BC00003

    AstraZeneca AB

    Advanced solid tumour

    phase 1 other active

    1 trial

  11. D5985C00008

    AstraZeneca AB

    Not applicable, healthy volunteers

    phase 1 other active

    1 trial

  12. D5985C00009

    AstraZeneca AB

    Not applicable, healthy volunteers

    phase 1 other active

    1 trial

  13. D6830C00004

    AstraZeneca AB

    Asthma

    phase 1 other active

    1 trial

  14. D702EC00001

    AstraZeneca AB

    Advanced Solid Tumors

    phase 1 other active

    1 trial

  15. D7260C00007

    AstraZeneca AB

    Not applicable, healthy volunteers

    phase 1 other active

    1 trial

  16. D740AC00001

    AstraZeneca AB

    Systemic Lupus Erythematosus, Rheumatoid Arthritis

    phase 1 other active

    1 trial

  17. D7860C00004

    AstraZeneca AB

    Chronic obstructive pulmonary disease

    phase 1 other active

    1 trial

  18. D7860C00005

    AstraZeneca AB

    Type 2 Diabetes Mellitus

    phase 1 other active

    1 trial

  19. D7930C00003

    AstraZeneca AB

    advanced liver fibrosis

    phase 1 other active

    1 trial

  20. D8210C00006

    AstraZeneca AB

    Asthma

    phase 1 other active

    1 trial

  21. D8330C00004

    AstraZeneca AB

    Heart failure with reduced ejection fraction, Renal impairment

    phase 1 small molecule active

    1 trial

  22. D8340C00001

    AstraZeneca AB

    PLN R14del Dilated Cardiomyopathy

    phase 1 other active

    1 trial

  23. D8530C00001

    AstraZeneca AB

    "Estrogen Receptor Positive HER2 Negative Advanced Breast Cancer"

    phase 1 other active

    1 trial

  24. D8990C00001

    AstraZeneca AB

    Platinum-resistant recurrent (PRR) ovarian cancer, Platinum-sensitive recurrent (PSR) ovarian cancer, Lung Adenocarcinoma, and endometrial cancer.

    phase 1 other active

    1 trial

  25. D8991C00002

    AstraZeneca AB

    Ovarian cancer Primary peritoneal cancer Fallopian tube cancer

    phase 1 other active

    1 trial

  26. D907HC00001

    AstraZeneca AB

    • Non-small cell lung cancer (Stage III, unresectable) • Small cell lung cancer (Limited stage) • Hepatocellular carcinoma (Unresectable) • Advanced or Metastatic non-small cell lung cancer

    phase 1 small molecule active

    1 trial

  27. D9090C00007

    AstraZeneca AB

    Moderate Renal Impairment, Heart Failure

    phase 1 other active

    1 trial

  28. D9090C00010

    AstraZeneca AB

    Impaired renal function

    phase 1 other active

    1 trial

  29. D9180C00006

    AstraZeneca AB

    Inflammation, Respiratory

    phase 1 other active

    1 trial

  30. D9180C00011

    AstraZeneca AB

    healthy volunteers

    phase 1 other active

    1 trial

  31. D926FC00001

    AstraZeneca AB

    Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial

  32. D933IC00001

    AstraZeneca AB

    Metastatic Non-Small Cell Lung Cancer (NSCLC)

    phase 1 other active

    1 trial

  33. D9440C00003

    AstraZeneca AB

    Healthy Volunteers, Renal Impairment and End Stage Kidney Disease

    phase 1 other active

    1 trial

  34. D9441C00001

    AstraZeneca AB

    Chronic Kidney disease, Atherosclerotic Cardiovascular Disease

    phase 1 other active

    1 trial

  35. D9441C00004

    AstraZeneca AB

    Cardiorenal disease

    phase 1 other active

    1 trial

  36. D9470C00001

    AstraZeneca AB

    CD123-Positive Hematological Malignancies: Module 1 focuses on R/R Acute Myeloid Leukemia and R/R Myelodysplastic Syndrome.

    phase 1 other active

    1 trial

  37. D9609C00001

    AstraZeneca AB

    Healthy Volunteers

    phase 1 other active

    1 trial

  38. D9640C00001

    AstraZeneca AB

    Rheumatoid Arthritis

    phase 1 other active

    1 trial

  39. D967JC00002

    AstraZeneca AB

    Metastatic Breast Cancer

    phase 1 small molecule active

    1 trial

  40. D967YC00001

    AstraZeneca AB

    Advanced or metastatic non-squamous non-small lung cancer (mNSCLC) with human epidermal growth factor receptor 2 (HER2) overexpression (OE)

    phase 1 other active

    1 trial

  41. D9690C00007

    AstraZeneca AB

    Crohn's disease

    phase 1 other active

    1 trial

  42. D9723C00002

    AstraZeneca AB

    advanced solid malignancies

    phase 1 other active

    1 trial

  43. D9961C00001

    AstraZeneca AB

    Systemic Lupus Erythematosus, Rheumatoid Arthritis, Idiopathic Inflammatory Myopathies

    phase 1 other active

    1 trial

  44. DA-5210 10/500mg

    Dong Wang

    Healthy

    phase 1 small molecule completed

    1 trial

  45. DAB

    CNS Pharmaceuticals

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  46. DBP-053-01

    Lacuna Pharma Pty Ltd

    Glioblastoma

    phase 1 other active

    1 trial

  47. DCVac-L

    NORTHWEST BIOTHERAPEUTICS INC

    Ovarian Cancer

    phase 1 mab completed

    1 trial

  48. DCVax-Direct

    NORTHWEST BIOTHERAPEUTICS INC

    Brain Metastases

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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