Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 31 of 99

  1. Ciprofloxacin XR + MMX Placebo

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  2. Cisplatin

    Regeneron UK Limited

    Head and Neck Cancer

    phase 1 small molecule active

    1 trial

  3. Cisplatin

    United Therapeutics Europe Ltd

    Advanced Cholangiocarcinoma

    phase 1 small molecule terminated

    1 trial

  4. Cisplatin

    BioMarin Pharmaceutical Australia Pty Ltd

    Solid Tumors

    phase 1 small molecule terminated

    1 trial

  5. Cisplatin

    AstraZeneca

    Inoperable Locally Advanced or Metastatic Biliary Tract Cancer

    phase 1 small molecule terminated

    1 trial

  6. Citalopram

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Depression

    phase 1 small molecule active

    1 trial

  7. Clarithromycin

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  8. Clarithromycin

    BRIGHT MINDS BIOSCIENCES INC.

    Drug-induced QT Prolongation

    phase 1 small molecule completed

    1 trial

  9. Clarithromycin

    Takeda

    Helicobacter Pylori

    phase 1 small molecule completed

    2 trials

  10. Clarithromycin ER 500 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  11. Clascoterone Cream 1%

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Acne Vulgaris

    phase 1 small molecule completed

    1 trial

  12. Clavulanic Acid

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence, in Remission

    phase 1 small molecule completed

    1 trial

  13. Clavulanic acid

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  14. Click-cleavable imaging in HER2-positive cancers (CleavHER trial).

    Disc Medicine

    HER2-positive tumors

    phase 1 other active

    1 trial

  15. Clifutinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Subject

    phase 1 small molecule active

    1 trial

  16. Clifutinib Besylate

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  17. Clifutinib with fed state

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Acute Myeloid Leukemia in Children

    phase 1 small molecule completed

    1 trial

  18. Clindamycin 300 mg capsule

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  19. Clinical Center Reference Endotoxin (CCRE)

    United Therapeutics Europe Ltd

    Healthy

    phase 1 small molecule completed

    1 trial

  20. Clopidogrel

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  21. Coadministration of GA2 Sporozoites With Adjuvants (CoGA)

    Disc Medicine

    Falciparum malaria

    phase 1 other active

    1 trial

  22. Cobimetinib

    Cardiff Oncology

    Locally Advanced Pancreatic Ductal Adenocarcinoma

    phase 1 small molecule active

    1 trial

  23. Cocaine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule completed

    3 trials

  24. Cocaine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Abuse

    phase 1 small molecule completed

    1 trial

  25. Cocaine (IV)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule active

    1 trial

  26. Cocaine Self-adminstration

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  27. Cocaine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Induced Sympathoexciation and Vasoconstriction

    phase 1 small molecule terminated

    1 trial

  28. Cognitive-Behavioral Therapy

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 1 other completed

    1 trial

  29. Cohort 1 - TMP-301

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule completed

    1 trial

  30. Cohort 1 BEM + Ruzasvir

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  31. Cohort 1: bococizumab 150 mg + rHuPH20

    HALOZYME THERAPEUTICS, INC.

    Healthy

    phase 1 mab terminated

    1 trial

  32. Comparison between ABP 234 and Keytruda® (Pembrolizumab)

    Amgen

    Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer

    phase 1 other active

    1 trial

  33. Comparison of Prefilled syringe and Autoinjector presentations of FYB202

    Fresenius Kabi Australia Pty Limited

    Chronic inflammatory diseases

    phase 1 other active

    1 trial

  34. Computer algorithm for ATTR

    Alnylam Netherlands B.V.

    Transthyretin Amyloidosis

    phase 1 other terminated

    1 trial

  35. Concurrent chemotherapy

    Sun Yat-sen University

    Locally Advanced Lung Carcinoma

    phase 1 small molecule completed

    1 trial

  36. Conditioning chemotherapy followed by AbTCR (anti-CD19/CD22)-T cell infusion

    The First People's Hospital of Lianyungang

    Diffuse Large B Cell Lymphoma (DLBCL)

    phase 1 small molecule active

    1 trial

  37. Control Group

    Tvardi Therapeutics

    Squamous Cell Carcinoma of Head and Neck

    phase 1 small molecule terminated

    1 trial

  38. Convalescent plasma

    Te Arai BioFarma Limited

    Convalescence

    phase 1 mab completed

    1 trial

  39. Cordyceps cicadae extract

    Hospital Authority, Hong Kong

    Myopia

    phase 1 mab completed

    1 trial

  40. Cordyceps cicadae extract

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Myopia

    phase 1 mab completed

    1 trial

  41. Cosibelimab

    TG THERAPEUTICS, INC.

    B-cell Non Hodgkin Lymphoma

    phase 1 small molecule terminated

    1 trial

  42. Custirsen

    Teva Pharma GmbH

    Cardiac Conduction and Repolarization

    phase 1 small molecule completed

    1 trial

  43. Custirsen, paclitaxel and carboplatin

    Teva Pharma GmbH

    Cancer

    phase 1 small molecule completed

    1 trial

  44. Cyclophosphamide

    Iovance Biotherapeutics B.V.

    Locally Advanced Melanoma

    phase 1 small molecule active

    1 trial

  45. Cyclophosphamide

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 1 small molecule active

    1 trial

  46. Cyclophosphamide

    Nektar Therapeutics UK Limited

    Recurrent Diffuse Large B-Cell Lymphoma

    phase 1 small molecule active

    1 trial

  47. Cyclophosphamide and Fludarabine

    Chongqing Precision Biotech Co., Ltd

    Lung Cancer, Nonsmall Cell, Recurrent

    phase 1 small molecule active

    1 trial

  48. Cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Addiction

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.