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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 3 of 99

  1. 15-Valent Pneumococcal Conjugate Vaccine

    BRIGHT MINDS BIOSCIENCES INC.

    Pneumonia, Pneumococcal

    phase 1 mab active

    1 trial

  2. 15/0483

    United Therapeutics Europe Ltd

    Head and Neck Fibrosis

    phase 1 other completed

    1 trial

  3. 1501-0002

    Boehringer Ingelheim

    Head and neck squamous cell carcinoma

    phase 1 other active

    1 trial

  4. 1505-0001

    Boehringer Ingelheim

    Metastatic pancreatic ductal adenocarcinoma (mPDAC)

    phase 1 other active

    1 trial

  5. 1507-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  6. 1509-0002

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  7. 1509-0003

    Boehringer Ingelheim

    Type 1 interferonopathies

    phase 1 other active

    1 trial

  8. 1509-0007

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  9. 1509-0010

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  10. 1509-0014

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  11. 1516-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  12. 1516-0002

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  13. 1516-0003

    Boehringer Ingelheim

    Attention deficit hyperactivity disorder, Borderline personality disorder

    phase 1 other active

    1 trial

  14. 1516-0004

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  15. 1519-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  16. 1519-0002

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  17. 1519-0004

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  18. 1524-0001

    Boehringer Ingelheim

    Metabolic Dysfunction-associated Steatohepatitis

    phase 1 other active

    1 trial

  19. 1526-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  20. 1527-0001

    Boehringer Ingelheim

    Melanoma, Solid tumours

    phase 1 other active

    1 trial

  21. 1530-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  22. 1530-0002

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  23. 1533-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  24. 1538-0001

    Boehringer Ingelheim

    advanced, unresectable and/or metastatic solid tumors

    phase 1 other active

    1 trial

  25. 153Sm-DOTMP

    Telix Innovations

    Bone Pain

    phase 1 small molecule active

    1 trial

  26. 15403/23-24

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetes Mellitus, Type 2

    phase 1 small molecule active

    1 trial

  27. 1543-0001

    Boehringer Ingelheim

    healthy volunteer trial

    phase 1 other active

    1 trial

  28. 17651

    Disc Medicine

    Locally advanced rectal cancer

    phase 1 other active

    1 trial

  29. 177Lu-DOTA-TLX591

    Telix Innovations

    Metastatic Prostate Cancer

    phase 1 mab completed

    1 trial

  30. 177Lu-TLX250 and Peposertib

    Telix Innovations

    Solid Tumor, Adult

    phase 1 other active

    1 trial

  31. 18F-FAPIBiotin

    The First People's Hospital of Lianyungang

    Malignant Neoplasm

    phase 1 small molecule active

    1 trial

  32. 18F-FDG

    The First People's Hospital of Lianyungang

    Multiple Myeloma and Malignant Plasma Cell Neoplasms

    phase 1 small molecule active

    1 trial

  33. 18F-PEG6-IPQA

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 1 small molecule completed

    1 trial

  34. 19(T2)28z1xx CAR T cells

    Takeda

    Diffuse Large B Cell Lymphoma

    phase 1 small molecule active

    1 trial

  35. 19(T2)28z1xx TRAC T cell

    Takeda

    B-Cell Lymphoma

    phase 1 mab active

    1 trial

  36. 19-02/MPA-S

    Alphapharm Pty Ltd

    Mild to moderate atopic dermatitis

    phase 1 small molecule active

    1 trial

  37. 1mg KHK7580

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  38. 2-4 of the drugs listed below

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Dependence

    phase 1 small molecule completed

    1 trial

  39. 2-4 of the drugs listed below

    BRIGHT MINDS BIOSCIENCES INC.

    Drug Dependence

    phase 1 small molecule completed

    1 trial

  40. 20 mg/kg TRU-016 + Rituximab

    Aptevo Therapeutics

    Chronic Lymphocytic Leukemia

    phase 1 mab terminated

    1 trial

  41. 200 mg GLPG0634 as capsules, fasted

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  42. 2001-0001

    Boehringer Ingelheim

    Advanced relapsed or refractory ovarian cancer, Advanced relapsed or refractory endometrial cancer, Advanced relapsed or refractory germ cell tumours

    phase 1 other active

    1 trial

  43. 2007-0001

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  44. 2012-0001

    Boehringer Ingelheim

    unresectable advanced or metastatic solid cancer

    phase 1 other active

    1 trial

  45. 20160323

    Amgen

    Small Cell Lung Cancer

    phase 1 other active

    1 trial

  46. 2017-004466-98

    Tonix Pharmaceuticals Holding

    Pain, Face

    phase 1 small molecule completed

    1 trial

  47. 2018-523-00US1

    Hutchmed Europe B.V.

    Lymphoma

    phase 1 other active

    1 trial

  48. 20180146

    Amgen

    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

    phase 1 other active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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