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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 27 of 99

  1. CLIN-60250-450

    Ipsen

    Not applicable

    phase 1 other active

    1 trial

  2. CLL1 and CD38 Dual-Target CAR-T Cell Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  3. CLN-049

    Cullinan Therapeutics

    Relapsed/Refractory Acute Myeloid Leukemia (AML)

    phase 1 small molecule active

    1 trial

  4. CLN-049-002

    Cullinan Therapeutics

    Acute Myeloid Leukemia (AML) with Measurable Residual Disease (MRD)

    phase 1 other active

    1 trial

  5. CLN-617

    Cullinan Therapeutics

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  6. CLN-619

    Cullinan Therapeutics

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  7. CLN-619

    Cullinan Therapeutics

    Multiple Myeloma

    phase 1 small molecule active

    1 trial

  8. CLN-619-001

    Cullinan Therapeutics

    Solid tumors, Non-Small Cell Lung Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer, breast cancer, gastrointestinal cancer

    phase 1 other active

    1 trial

  9. CLN-978

    Cullinan Therapeutics

    Rheumatoid Arthritis (RA

    phase 1 small molecule active

    1 trial

  10. CLN-978

    Cullinan Therapeutics

    SLE

    phase 1 small molecule active

    1 trial

  11. CLN-978

    Cullinan Therapeutics

    Sjögren

    phase 1 small molecule active

    1 trial

  12. CLN-978

    Cullinan Therapeutics

    NHL

    phase 1 small molecule active

    1 trial

  13. CLN-978-RA-101

    Cullinan Therapeutics

    Treatment-Refractory Rheumatoid Arthritis

    phase 1 other active

    1 trial

  14. CLN-978-SJ-101

    Cullinan Therapeutics

    Sjogren's Disease

    phase 1 other active

    1 trial

  15. CLN-978-SL-101

    Cullinan Therapeutics

    Systemic Lupus Erythematosus

    phase 1 other active

    1 trial

  16. CLP22001

    Alphapharm Pty Ltd

    Bioequivalence trial in healthy volunteers

    phase 1 other active

    1 trial

  17. CLP24001

    Alphapharm Pty Ltd

    Bioequivalence trial in healthy volunteers

    phase 1 other active

    1 trial

  18. CLR 131

    Cellectar Biosciences

    Head and Neck Cancer

    phase 1 small molecule completed

    1 trial

  19. CLR 131

    Cellectar Biosciences

    Pediatric Solid Tumor

    phase 1 small molecule active

    1 trial

  20. CLR 131

    Cellectar Biosciences

    High-Grade Glioma

    phase 1 small molecule active

    1 trial

  21. CLTP001A12101

    Novartis Pharmaceuticals

    Healthy volunteers

    phase 1 other active

    1 trial

  22. CM-101

    Chemomab Therapeutics

    Nonalcoholic Steatohepatitis (NASH)

    phase 1 small molecule completed

    1 trial

  23. CM336 (BCMA/CD3 bispecific antibody)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed Refractory Multiple Myeloma (RRMM)

    phase 1 mab active

    1 trial

  24. CMP-001

    Regeneron UK Limited

    Malignant Melanoma

    phase 1 small molecule completed

    1 trial

  25. CMP-001

    Regeneron UK Limited

    Non Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  26. CMP-CPS-001

    Camp4 Therapeutics Corp

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  27. CMV-TCR-T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    CMV Infection or Reactivation After Allogenic HSCT

    phase 1 mab completed

    1 trial

  28. CMX001

    Jazz Pharmaceuticals Ireland Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  29. CMX001

    Jazz Pharmaceuticals Ireland Limited

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  30. CMX157

    Jazz Pharmaceuticals Ireland Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  31. CN0140003

    Bristol-Myers Squibb Australia Pty Ltd

    Neuropsychiatric indications and potentially other conditions

    phase 1 other active

    1 trial

  32. CNCT19 CAR-T cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 mab active

    1 trial

  33. CNCT19 cell injection

    Juventas Cell Therapy

    Neurological Autoimmune Diseases

    phase 1 mab active

    1 trial

  34. CNTY-101

    Century Therapeutics

    R/R CD19-Positive B-Cell Malignancies

    phase 1 mab terminated

    1 trial

  35. CNTY-101

    Century Therapeutics

    Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial

  36. CNTY-101-151-01

    Century Therapeutics

    systemic lupus erythematosus [SLE]/lupus nephritis [LN], idiopathic inflammatory myopathy [IIM], and diffuse cutaneous systemic sclerosis [DcSSc]

    phase 1 other active

    1 trial

  37. CNTY-LTFU-01

    Century Therapeutics

    Hematological or solid tumor malignancies or autoimmune diseases

    phase 1 other active

    1 trial

  38. CO42800

    Hoffmann-La Roche

    Locally Advanced or Metastatic Solid Tumors

    phase 1 other active

    1 trial

  39. CO43805

    Hoffmann-La Roche

    Non-Hodgkin Lymphoma

    phase 1 other active

    1 trial

  40. COJR520A12101

    Novartis Pharmaceuticals

    Chronic Kidney Disease

    phase 1 other active

    1 trial

  41. COR1167-101

    Lacuna Pharma Pty Ltd

    Chronic heart failure

    phase 1 other active

    1 trial

  42. COR1167-102

    Lacuna Pharma Pty Ltd

    Chronic Heart Failure

    phase 1 other active

    1 trial

  43. COR1389-101

    Lacuna Pharma Pty Ltd

    Obesity / Right heart failure (healthy participants)

    phase 1 other active

    1 trial

  44. CORT113176

    CORCEPT THERAPEUTICS INC

    Healthy Adults

    phase 1 small molecule completed

    1 trial

  45. CORT113176 Lipid Capsule Formulation

    CORCEPT THERAPEUTICS INC

    Healthy Adults

    phase 1 small molecule completed

    1 trial

  46. CORT118335 Oral

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  47. CORT118335, 25 mg

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  48. CORT125134

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    2 trials

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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