Friday, July 10, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 2 of 99

  1. 1397-0021

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  2. 1397-0022

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  3. 1397-0029

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  4. 14-XC-CL

    Lacuna Pharma Pty Ltd

    Parkinson’s Disease

    phase 1 other active

    1 trial

  5. 14028 injection

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes

    phase 1 mab completed

    1 trial

  6. 1403-0001

    Boehringer Ingelheim

    Advanced or metastatic solid tumors

    phase 1 other active

    1 trial

  7. 1403-0002

    Boehringer Ingelheim

    advanced solid tumors

    phase 1 other active

    1 trial

  8. 1403-0004

    Boehringer Ingelheim

    Solid cancer tumors

    phase 1 other active

    1 trial

  9. 1404-0008

    Boehringer Ingelheim

    Overweight, Obesity

    phase 1 other active

    1 trial

  10. 1404-0009

    Boehringer Ingelheim

    Renal impairment (mild, moderate and severe), Healthy

    phase 1 other active

    1 trial

  11. 1404-0011

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  12. 1404-0015

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  13. 1404-0074

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  14. 1404-0099

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  15. 1404-0103

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  16. 1404-0118

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  17. 14040047

    Boehringer Ingelheim

    No targeted indication. Male and female subjects with obesity.

    phase 1 other active

    1 trial

  18. 1434-0005

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  19. 1434-0006

    Boehringer Ingelheim

    healthy volunteer trial

    phase 1 other active

    1 trial

  20. 1434-0021

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  21. 14341

    Disc Medicine

    Glioma

    phase 1 other active

    1 trial

  22. 1438-0001

    Boehringer Ingelheim

    Small Cell Lung Carcinoma and other neuroendocrine neoplasms expressing DLL3

    phase 1 other active

    1 trial

  23. 1438-0003

    Boehringer Ingelheim

    Glioma expressing DLL3

    phase 1 other active

    1 trial

  24. 1438-0007

    Boehringer Ingelheim

    Extra-pulmonary neuroendocrine carcinoma (epNEC), Neuroendocrine carcinoma (NEC) with unknown primary site, pulmonary Large cell neuroendocrine carcinoma (LCNEC)

    phase 1 other active

    1 trial

  25. 1438-0008

    Boehringer Ingelheim

    Extensive-stage small cell lung carcinoma (ES-SCLC)

    phase 1 other active

    1 trial

  26. 1438-0009

    Boehringer Ingelheim

    relapsed/refractory extensive stage - small cell lung cancer (ES-SCLC)

    phase 1 other active

    1 trial

  27. 1443-0002

    Boehringer Ingelheim

    head and neck squamous cell carcinoma (HNSCC), hepatocellular carcinoma

    phase 1 other active

    1 trial

  28. 1443-0003

    Boehringer Ingelheim

    non-small cell lung cancer or, melanoma, head and neck squamous cell carcinoma

    phase 1 other active

    1 trial

  29. 1447-0007

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  30. 145 mg/m2 NKTR 102

    Nektar Therapeutics UK Limited

    Advanced or Metastatic Solid Tumors in Patients With Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  31. 1454-0015

    Boehringer Ingelheim

    colorectal carcinoma (CRC)

    phase 1 other active

    1 trial

  32. 1456-0001

    Boehringer Ingelheim

    solid tumors

    phase 1 other active

    1 trial

  33. 1458-0006

    Boehringer Ingelheim

    Obesity

    phase 1 other active

    1 trial

  34. 1463-0001

    Boehringer Ingelheim

    Advanced head and neck cancer

    phase 1 other active

    1 trial

  35. 1472-0001

    Boehringer Ingelheim

    solid tumour harbouring G12C mutation

    phase 1 other active

    1 trial

  36. 1474-0002

    Boehringer Ingelheim

    Plaque psoriasis

    phase 1 other active

    1 trial

  37. 1479-0001

    Boehringer Ingelheim

    Solid tumours with HER2 aberrations, Non-small cell lung cancer

    phase 1 other active

    1 trial

  38. 1479-0014

    Boehringer Ingelheim

    Pharmacokinetic trial

    phase 1 other active

    1 trial

  39. 1479-0015

    Boehringer Ingelheim

    Pharmacokinetic trial

    phase 1 other active

    1 trial

  40. 1479-0019

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  41. 1479-0047

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  42. 1480-0001

    Boehringer Ingelheim

    Advanced solid tumours

    phase 1 other active

    1 trial

  43. 1485-0013

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  44. 1490-0006

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  45. 1493-0008

    Boehringer Ingelheim

    Healthy volunteer trial

    phase 1 other active

    1 trial

  46. 14C-CORT125281

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  47. 14C-VX-993

    Vertex Pharmaceuticals (Australia) Pty.

    Pain

    phase 1 small molecule completed

    1 trial

  48. 14C-XEN1101

    Xenon Pharmaceuticals

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.