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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 17 of 99

  1. Ataluren

    PTC THERAPEUTICS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  2. Atezolizumab

    Hoffmann-La Roche

    Advanced Ovarian Cancer

    phase 1 small molecule terminated

    1 trial

  3. Atezolizumab

    Jazz Pharmaceuticals Ireland Limited

    Endometrial Cancer

    phase 1 small molecule active

    1 trial

  4. Atorvastatin

    Aligos Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  5. Atorvastatin

    Madrigal Pharmaceuticals EU Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  6. Atorvastatin

    Lakefront Biotherapeutics NV

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial

  7. Atovaquone Oral Suspension

    United Therapeutics Europe Ltd

    Locally Advanced Non-Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  8. Atu027

    Silence Therapeutics plc

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  9. Atumelnant

    Crinetics Pharmaceuticals Europe GmbH

    Healthy Volunteers

    phase 1 small molecule active

    2 trials

  10. Autologous Bone Marrow-derived Mononuclear Cells

    Regeneron Ireland Designated Activity Company (DAC)

    Congenital Heart Disease

    phase 1 mab completed

    1 trial

  11. Autologous Engineered Urethral Construct

    United Therapeutics Europe Ltd

    Urologic Diseases

    phase 1 mab active

    1 trial

  12. Autologous Human Schwann Cell

    United Therapeutics Europe Ltd

    Peripheral Nerve Injury

    phase 1 mab active

    1 trial

  13. Autologous Natural Killer Cell Therapy

    Hospital Authority, Hong Kong

    Hepatocellular Carcinoma

    phase 1 small molecule active

    1 trial

  14. Autologous differentiated myocyte transplantation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metabolic Disease

    phase 1 mab active

    1 trial

  15. Autologous mononuclear cells

    Regeneron Ireland Designated Activity Company (DAC)

    Congenital Heart Disease, SRV Dependent

    phase 1 mab active

    1 trial

  16. Autologous tissue engineered corpora

    United Therapeutics Europe Ltd

    Urologic Diseases

    phase 1 mab active

    1 trial

  17. Autologous tumor-infiltrating lymphocyte cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Solid Tumor

    phase 1 mab terminated

    1 trial

  18. Autologous γδT cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Hodgkin's Lymphoma

    phase 1 mab active

    1 trial

  19. Automated Contingency Management (ACM) software

    BRIGHT MINDS BIOSCIENCES INC.

    Opiate-Replacement Therapy

    phase 1 other completed

    1 trial

  20. Axatilimab

    Syndax Pharmaceuticals

    Solid Tumor

    phase 1 small molecule completed

    1 trial

  21. Azacitidine

    PMV Pharmaceuticals

    Myelodysplastic Syndrome

    phase 1 small molecule active

    1 trial

  22. Azathioprine 50Mg Tab

    Blackmores Limited

    Therapeutic Equivalency

    phase 1 small molecule completed

    1 trial

  23. Azenosertib

    Zentalis Pharmaceuticals

    Solid Tumor

    phase 1 small molecule active

    2 trials

  24. Azenosertib

    Zentalis Pharmaceuticals

    Osteosarcoma

    phase 1 small molecule completed

    1 trial

  25. Azercabtagene zapreleucel (azer-cel)

    TG THERAPEUTICS, INC.

    B-cell Mediated Autoimmune Disorders

    phase 1 small molecule active

    1 trial

  26. Azilsartan (Zhaoke)

    Lee's Pharmaceutical Limited

    Bioequivalence of Two Azilsartan Formulations

    phase 1 small molecule completed

    1 trial

  27. Azilsartan medoxomil (TAK-491)

    Takeda

    Hypertension

    phase 1 small molecule terminated

    1 trial

  28. Azithromycin

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  29. Azithromycin 600 mg Tablet

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  30. Azithromycin Pill

    Arrowhead Pharmaceuticals Ireland Limited

    Infections

    phase 1 small molecule active

    1 trial

  31. B/F/TAF

    Gilead Sciences Ireland UC

    HIV-1-infection

    phase 1 small molecule completed

    1 trial

  32. B06CS

    Advicenne S.A.

    distal renal tubular acidosis (dRTA)

    phase 1 other active

    1 trial

  33. B3461114

    Pfizer Australia Pty Ltd

    aransthyretin amyloid cardiomyopathy

    phase 1 small molecule active

    1 trial

  34. B3461115

    Pfizer Australia Pty Ltd

    Transthyretin amyloidosis

    phase 1 other active

    1 trial

  35. B3461131

    Pfizer Australia Pty Ltd

    Transthyretin amyloidosis

    phase 1 other active

    1 trial

  36. BAL2420-CP-101

    Lacuna Pharma Pty Ltd

    Severe infections caused by Gram-negative bacteria

    phase 1 other active

    1 trial

  37. BAO-G

    The First People's Hospital of Lianyungang

    Thoracoabdominal Aortic Aneurysm

    phase 1 other active

    1 trial

  38. BAX 826

    Takeda

    Hemophilia A

    phase 1 mab completed

    1 trial

  39. BAY2965501

    Bayer HealthCare AG

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  40. BBO-10203

    BridgeBio Oncology Therapeutics

    Solid Tumor, Adult

    phase 1 small molecule active

    1 trial

  41. BBO-11818

    BridgeBio Oncology Therapeutics

    Non-Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  42. BBO-8520

    BridgeBio Oncology Therapeutics

    Non-small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  43. BBP-398

    BridgeBio Oncology Therapeutics

    Solid Tumor, Adult

    phase 1 small molecule terminated

    1 trial

  44. BBP-398 (Formerly known as IACS-15509)

    BridgeBio Oncology Therapeutics

    Tumor, Solid

    phase 1 small molecule terminated

    1 trial

  45. BBP-398 with nivolumab

    BridgeBio Oncology Therapeutics

    Non Small Cell Lung Cancer

    phase 1 small molecule terminated

    1 trial

  46. BBP-671

    BridgeBio Oncology Therapeutics

    Healthy Volunteers

    phase 1 small molecule terminated

    1 trial

  47. BBP-711

    BridgeBio Oncology Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  48. BC-101

    BRIGHT MINDS BIOSCIENCES INC.

    Nasolabial Fold Wrinkles

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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