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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 15 of 99

  1. Active Cannabis

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule active

    1 trial

  2. Active Delta-9-THC

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 1 small molecule completed

    1 trial

  3. Ad-RTS-hIL-12

    Alaunos Therapeutics

    Glioblastoma Multiforme

    phase 1 mab completed

    1 trial

  4. Ad26.COV2.S

    Janssen Cilag International NV

    Healthy

    phase 1 mab completed

    1 trial

  5. Ad5-CB-CFTR

    Ultragenyx UK Limited

    Cystic Fibrosis

    phase 1 gene therapy completed

    1 trial

  6. Ad5-EBOV

    Jian Li

    Ebola Virus Disease

    phase 1 mab completed

    1 trial

  7. AdV-tk

    Candel Therapeutics

    Pancreatic Adenocarcinoma

    phase 1 mab completed

    1 trial

  8. AdV-tk

    Candel Therapeutics

    Malignant Glioma

    phase 1 mab completed

    2 trials

  9. AdV-tk

    Candel Therapeutics

    Glioma, Malignant

    phase 1 mab completed

    1 trial

  10. AdV-tk + valacyclovir

    Candel Therapeutics

    Malignant Pleural Effusion

    phase 1 mab completed

    1 trial

  11. Adapalene

    Teva Pharma GmbH

    Acne Vulgaris

    phase 1 small molecule completed

    1 trial

  12. Adebrelimab

    The First People's Hospital of Lianyungang

    Biliary Tract Malignancies

    phase 1 small molecule active

    1 trial

  13. Adjuvant/Excipients

    Takeda

    Norovirus

    phase 1 small molecule completed

    1 trial

  14. Administration of UI087

    United Therapeutics Europe Ltd

    Diabetes Mellitus (Type 2)

    phase 1 small molecule active

    1 trial

  15. Administration of the malaria inoculum

    CNS Pharmaceuticals

    Malaria

    phase 1 mab completed

    1 trial

  16. Adolescent Methamphetamine Treament (AMT)

    BRIGHT MINDS BIOSCIENCES INC.

    Behavior and Mental Disorders

    phase 1 other completed

    1 trial

  17. Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes (TIL)

    United Therapeutics Europe Ltd

    Urothelial Carcinoma

    phase 1 mab active

    1 trial

  18. Aflibercept

    Regeneron UK Limited

    Neovascular Macular Degeneration

    phase 1 small molecule completed

    1 trial

  19. Aflibercept

    Regeneron UK Limited

    Irvine-Gass Syndrome

    phase 1 small molecule terminated

    1 trial

  20. Aflibercept (AVE0005)

    Regeneron UK Limited

    Neoplasm Malignant

    phase 1 small molecule completed

    2 trials

  21. Aflibercept every 2 months

    Regeneron UK Limited

    Radiation Retinopathy

    phase 1 small molecule completed

    1 trial

  22. Airway Bypass

    CATALYST PHARMACEUTICALS, INC.

    Emphysema or COPD

    phase 1 other active

    1 trial

  23. Akk Gut Bacteria Supplement

    The First People's Hospital of Lianyungang

    Premature Ovarian Failure (POF)

    phase 1 other active

    1 trial

  24. Albuterol dry powder inhaler

    Teva Pharma GmbH

    Asthma

    phase 1 small molecule completed

    1 trial

  25. Alcohol

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol Drinking

    phase 1 small molecule completed

    1 trial

  26. Alcohol

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use

    phase 1 small molecule completed

    1 trial

  27. Alcohol + Caffeine Beverage

    BRIGHT MINDS BIOSCIENCES INC.

    Alcohol or Other Drugs Effects

    phase 1 small molecule completed

    1 trial

  28. Alendronate Sodium Tablets 70mg

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  29. Alirocumab

    Regeneron UK Limited

    Sepsis

    phase 1 small molecule completed

    1 trial

  30. Alirocumab

    Regeneron UK Limited

    Stroke

    phase 1 small molecule terminated

    1 trial

  31. Alirocumab (Solution)

    Regeneron UK Limited

    Hypercholesterolemia

    phase 1 small molecule completed

    1 trial

  32. Alisertib

    Takeda

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  33. Alisertib

    Takeda

    Advanced Solid Tumors

    phase 1 small molecule completed

    7 trials

  34. Alisertib

    Takeda

    B-cell Follicular Lymphoma

    phase 1 small molecule completed

    1 trial

  35. All-trans retinoic acid

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  36. Allo-depleted lymphocyte infusion

    Lxo Ireland Designated Activity Company

    Transplant-Related Hematologic Malignancy

    phase 1 other terminated

    1 trial

  37. Allogeneic (MSC's) Application to the Burn Wounds

    United Therapeutics Europe Ltd

    Skin Burn Degree Second

    phase 1 mab completed

    1 trial

  38. Allogeneic CD19/BCMA-targeted CAR-γδT cell injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Refractory/Relapsed Systemic Lupus Erythematosus

    phase 1 mab active

    1 trial

  39. Allogeneic Cardiosphere-Derived Cells (CDCs)

    CAPRICOR THERAPEUTICS, INC.

    Dilated Cardiomyopathy (DCM)

    phase 1 mab active

    1 trial

  40. Allogeneic MSC

    United Therapeutics Europe Ltd

    Mesenchymal Stromal Cells

    phase 1 mab completed

    1 trial

  41. Allogeneic anti-CD7 CAR-T cells (BEAM-201)

    Beam Therapeutics

    T-Cell Acute Lymphoblastic Leukemia/Lymphoma

    phase 1 mab active

    1 trial

  42. Alogliptin

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  43. Alogliptin

    Takeda

    Pharmacokinetics and Pharmacodynamics

    phase 1 small molecule completed

    1 trial

  44. Alprazolam Extended-Release 3 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  45. AmBisome liposomale amfotericine B for Chronic pulmonary aspergillosis

    Disc Medicine

    Chronic pulmonary aspergillosis

    phase 1 small molecule active

    1 trial

  46. Amitriptyline Hydrochloride 25Mg Tablet（Hunan Dongting）

    The First People's Hospital of Lianyungang

    Depressive Disorder

    phase 1 small molecule completed

    1 trial

  47. Amlodipine Besylate

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  48. Amlodipine-benazepril 10 mg-20 mg capsules

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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