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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 14 of 99

  1. AT-527 550 mg + midazolam

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  2. AT-527 Formulation 1

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  3. AT-527 fasted

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  4. AT-752

    Atea Pharmaceuticals

    Dengue

    phase 1 small molecule completed

    2 trials

  5. ATA3219

    Evidence Based Cataract Study Group

    Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

    phase 1 small molecule terminated

    1 trial

  6. ATA3219

    Evidence Based Cataract Study Group

    Lupus Nephritis

    phase 1 small molecule terminated

    1 trial

  7. ATAFENOVIR 200 MG KAPSUL

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule active

    1 trial

  8. ATDC-PICI

    The George Institute

    Kidney trasplants

    phase 1 other active

    1 trial

  9. ATG-010 and ATG-008

    Shanghai Antengene Corporation Limited

    Relapsed/Refractory Diffuse Large B-cell Lymphoma

    phase 1 other terminated

    1 trial

  10. ATHENA CAR-T

    The First People's Hospital of Lianyungang

    Lupus Erythematosus, Systemic

    phase 1 mab active

    1 trial

  11. ATI-052-ASTH-101

    Aclaris Therapeutics

    Mild to Moderate Asthma

    phase 1 other active

    1 trial

  12. ATI-1013 (0.2 g)

    BRIGHT MINDS BIOSCIENCES INC.

    Thromboangiitis Obliterans (Buerger's Disease)

    phase 1 mab active

    1 trial

  13. ATI-2231

    Aclaris Therapeutics

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  14. ATRA

    United Therapeutics Europe Ltd

    Pancreatic Adenocarcinoma

    phase 1 small molecule completed

    1 trial

  15. AU-011

    Aura Biosciences

    Non-muscle-invasive Bladder Cancer

    phase 1 small molecule active

    1 trial

  16. AUTO1-MS1

    Autolus GmbH

    Refractory Progressive Multiple Sclerosis

    phase 1 other active

    1 trial

  17. AUTO1-SL1

    Autolus GmbH

    Severe, Refractory Systemic Lupus Erythematosus

    phase 1 other active

    1 trial

  18. AV-101

    BRIGHT MINDS BIOSCIENCES INC.

    Neuropathic Pain

    phase 1 small molecule completed

    1 trial

  19. AV-101

    Vistagen Therapeutics

    Drug Drug Interaction

    phase 1 small molecule active

    1 trial

  20. AVE0005 (aflibercept)

    Regeneron UK Limited

    Colorectal Neoplasms

    phase 1 small molecule completed

    1 trial

  21. AVI-4020 Injection

    Sarepta Therapeutics

    West Nile Fever

    phase 1 small molecule terminated

    1 trial

  22. AVI-4020 Injection

    Sarepta Therapeutics

    West Nile Virus

    phase 1 small molecule completed

    1 trial

  23. AVI-4065 Injection

    Sarepta Therapeutics

    Encephalitis

    phase 1 small molecule completed

    1 trial

  24. AVI-4126 Injection (RESTEN-NG®)

    Sarepta Therapeutics

    Neoplasms

    phase 1 small molecule completed

    1 trial

  25. AVI-6003

    Sarepta Therapeutics

    Marburg Hemorrhagic Fever

    phase 1 small molecule completed

    1 trial

  26. AVI-7100

    Sarepta Therapeutics

    Influenza

    phase 1 small molecule terminated

    1 trial

  27. AVI-7288

    Sarepta Therapeutics

    Marburg Hemorrhagic Fever

    phase 1 small molecule completed

    1 trial

  28. AVI-7537

    Sarepta Therapeutics

    Ebola Hemorrhagic Fever

    phase 1 small molecule terminated

    1 trial

  29. AVICOD 200 MG Film Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule active

    1 trial

  30. AVN-944 capsules for oral administration

    Vertex Pharmaceuticals (Australia) Pty.

    Acute Leukemia

    phase 1 small molecule completed

    1 trial

  31. AZD0449

    AstraZeneca

    Asthma

    phase 1 small molecule completed

    1 trial

  32. AZD0530

    AstraZeneca

    Solid Tumor

    phase 1 small molecule completed

    1 trial

  33. AZD2014 3 on/4 off & weekly paclitaxel

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  34. AZD3514

    AstraZeneca

    Prostate Cancer

    phase 1 small molecule completed

    1 trial

  35. AZD5363+Olaparib+Durvalumab

    Hospital Authority, Hong Kong

    Solid Tumor, Adult

    phase 1 small molecule active

    1 trial

  36. AZD5462-D9090C00012

    AstraZeneca AB

    Chronic Heart Failure

    phase 1 other active

    1 trial

  37. AZD5492

    AstraZeneca AB

    B-Cell Malignancies

    phase 1 small molecule active

    1 trial

  38. AZD6244

    AstraZeneca

    Neoplasms,

    phase 1 small molecule completed

    1 trial

  39. AZD7762

    AstraZeneca

    Cancer

    phase 1 small molecule terminated

    1 trial

  40. AZD9150

    IONIS PHARMACEUTICALS INC

    Advanced Adult Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  41. Abatacept

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Dermatomyositis

    phase 1 small molecule active

    1 trial

  42. Ablation procedure and/or cardioversion

    Rhythm Pharmaceuticals Netherlands B.V.

    Atrial Fibrillation

    phase 1 other completed

    1 trial

  43. Acceptance and Commitment Therapy

    United Therapeutics Europe Ltd

    Stroke

    phase 1 other completed

    1 trial

  44. Aceclidine + Brimonidine

    LENZ Therapeutics

    Eye Diseases

    phase 1 small molecule completed

    1 trial

  45. Acetadote

    CUMBERLAND PHARMACEUTICALS INC

    Glioblastoma

    phase 1 small molecule active

    1 trial

  46. Acetaminophen

    Janssen Cilag International NV

    Healthy

    phase 1 small molecule completed

    1 trial

  47. Acetazolamide

    Ultragenyx UK Limited

    Andersen-Tawil Syndrome

    phase 1 small molecule terminated

    1 trial

  48. Acidform 5 g

    Evofem Biosciences

    Healthy

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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