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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 4,713
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 13 of 99

  1. APVO210

    Aptevo Therapeutics

    Psoriasis

    phase 1 mab terminated

    1 trial

  2. APVO436

    Aptevo Therapeutics

    AML

    phase 1 mab active

    2 trials

  3. APVO436

    Aptevo Therapeutics

    Acute Myeloid Leukemia (AML)

    phase 1 small molecule active

    1 trial

  4. ARAVA® 20 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  5. ARC-12

    Arcus Biosciences

    Multiple Myeloma, Diffuse large B cell lymphoma (DLBCL), Esophageal Cancer, Gastroesophageal Junction Adenocarcinoma, Melanoma, Advanced Solid Tumor, Gastrointestinal (GI) cancer, Hematological (heme) cancer, Gynecological (Gyn) cancer, Non-small cell lung cancer (NSCLC), Non-Hodgkin Lymphoma, Gastric Cancer, Cervical Cancer

    phase 1 other active

    1 trial

  6. ARC-20

    Arcus Biosciences

    Solid Tumors, Clear Cell Renal Cell Carcinoma

    phase 1 other active

    1 trial

  7. ARC-520

    Arrowhead Pharmaceuticals Ireland Limited

    Healthy

    phase 1 small molecule completed

    2 trials

  8. ARC-521 Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Hepatitis B

    phase 1 small molecule terminated

    1 trial

  9. ARCT-2138

    Arcturus Therapeutics Holdings

    Influenza, Human

    phase 1 mab completed

    1 trial

  10. ARCT-2304

    Arcturus Therapeutics Holdings

    Influenza, Human

    phase 1 mab completed

    1 trial

  11. ARGX-113-2405

    argenx

    not applicable

    phase 1 other active

    1 trial

  12. ARISE with AR

    BRIGHT MINDS BIOSCIENCES INC.

    Pediatric Cancer

    phase 1 other active

    1 trial

  13. ARN-75039 oral capsules

    United Therapeutics Europe Ltd

    Healthy Adult Participants

    phase 1 small molecule completed

    1 trial

  14. ARO-AAT Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Alpha 1-Antitrypsin Deficiency

    phase 1 small molecule completed

    1 trial

  15. ARO-ANG3

    Arrowhead Pharmaceuticals Ireland Limited

    Dyslipidemias

    phase 1 small molecule completed

    1 trial

  16. ARO-APOC3

    Arrowhead Pharmaceuticals Ireland Limited

    Hypertriglyceridemia

    phase 1 small molecule completed

    1 trial

  17. ARO-ATXN2 Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Spinocerebellar Ataxia Type 2

    phase 1 small molecule active

    1 trial

  18. ARO-CFB

    Arrowhead Pharmaceuticals Ireland Limited

    IgA Nephropathy

    phase 1 small molecule completed

    1 trial

  19. ARO-HIF2

    Arrowhead Pharmaceuticals Ireland Limited

    Clear Cell Renal Cell Carcinoma

    phase 1 small molecule completed

    1 trial

  20. ARO-RAGE Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Asthma

    phase 1 small molecule completed

    1 trial

  21. ARO-SOD1 Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Amyotrophic Lateral Sclerosis

    phase 1 small molecule terminated

    1 trial

  22. ARQ 197

    KYOWA KIRIN AUSTRALIA PTY LTD

    Advanced Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  23. ARQ-151 cream 0.15%

    Arcutis Biotherapeutics

    Atopic Dermatitis (Eczema)

    phase 1 small molecule completed

    1 trial

  24. ARQ-151- cream 0.3%

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 1 small molecule completed

    1 trial

  25. ARQ-154 Foam 0.3%

    Arcutis Biotherapeutics

    Psoriasis

    phase 1 small molecule completed

    1 trial

  26. ARQ-234

    Arcutis Biotherapeutics

    Atopic Dermatitis (AD)

    phase 1 mab active

    1 trial

  27. ARS-1 with URTI

    Ars Pharmaceuticals Irl Limited

    Upper Respiratory Tract Infection

    phase 1 small molecule completed

    1 trial

  28. ART-I02

    BRIGHT MINDS BIOSCIENCES INC.

    Arthritis, Rheumatoid

    phase 1 gene therapy active

    1 trial

  29. ARV-BA-001

    Lacuna Pharma Pty Ltd

    Healthy volunteers

    phase 1 other active

    1 trial

  30. AS/BW/ENE-21/0003

    Ultragenyx UK Limited

    Latrodectism

    phase 1 small molecule completed

    1 trial

  31. ASC30

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Weight Management

    phase 1 small molecule completed

    1 trial

  32. ASC47

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Weight Management

    phase 1 small molecule completed

    1 trial

  33. ASP1941

    Astellas Pharma Inc

    Healthy

    phase 1 small molecule completed

    1 trial

  34. ASP8062

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule completed

    1 trial

  35. ASP8082

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule completed

    1 trial

  36. ASP8374

    Regeneron UK Limited

    Glioblastoma

    phase 1 small molecule completed

    1 trial

  37. ASTX660

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  38. ASTX727-03

    Taiho Pharma Netherlands B.V.

    Myelodysplastic Syndromes (MDS)

    phase 1 small molecule active

    1 trial

  39. ASTX727-17

    Taiho Pharma Netherlands B.V.

    Acute myeloid lymphoma (AML), myelodysplastic syndrome (MDS), or solid tumors

    phase 1 other active

    1 trial

  40. ASTX727-18

    Taiho Pharma Netherlands B.V.

    Solid tumor, Acute myeloid lymphoma (AML), Myelodysplastic syndrome (MDS)

    phase 1 other active

    1 trial

  41. AT-01B-006

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  42. AT-301B

    ATOSSA THERAPEUTICS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  43. AT-527

    Atea Pharmaceuticals

    Chronic Hepatitis C

    phase 1 small molecule completed

    1 trial

  44. AT-527

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  45. AT-527

    Atea Pharmaceuticals

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  46. AT-527 (R07496998)

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  47. AT-527 + digoxin

    Atea Pharmaceuticals

    Healthy Volunteers Study

    phase 1 small molecule completed

    1 trial

  48. AT-527 550 mg + cyclosporine

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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