Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 12144876

    Security mechanisms for radiopharmaceutical elution system and elution process

    Jubilant Draximage Inc. · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12145939

    Substituted [1,2,4]triazolo[4,3-a]pyrazines as ion channel modulators

    PRAXIS PRECISION MEDICINES, INC. · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12144881

    Cosmetic composition containing α-mangostin, method for preparation, and uses thereof

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12144890

    Manufacturing of bupivacaine multivesicular liposomes

    Pacira Pharmaceuticals, Inc. · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12145922

    Selective D3 dopamine receptor agonists and methods of their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12145963

    Phenothiazine derivatives and uses thereof

    CAMP4 Therapeutics Corporation · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12145968

    Recombinant HIV-1 envelope proteins and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12145973

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12145974

    Dual-target fusion proteins comprising FGF21 and GLP-1, connected through a Fc portion of an immunoglobulin

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12146139

    Oligonucleotide interference treatments of prostate cancer

    The Board of Regents of the University of Oklahoma · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12144869

    Anti-ROR1 antibody conjugates, compositions comprising anti ROR1 antibody conjugates, and methods of making and using anti-ROR1 antibody conjugates

    Sutro Biopharma, Inc. · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 12145925

    Phthalazine derivatives as inhibitors of PARP1, PARP2, and/or tubulin useful for the treatment of cancer

    The Regents of the University of California · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12145944

    Imidazopyrimidines as EED inhibitors and the use thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 14 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12152034

    FGFR inhibitors and methods of making and using the same

    Relay Therapeutics, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12152242

    CRISPR therapy

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12152262

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12152038

    Vasopressin receptor antagonists and products and methods related thereto

    Neumora Therapeutics, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12150461

    Nicotinamide adenine dinucleotide (NAD) compositions, methods of manufacturing thereof, and methods of use thereof

    Sovida Solutions Ltd. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12150959

    Chimeric antigen receptors with BCMA specificity and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12152071

    EGFL6 specific monoclonal antibodies and methods of their use

    The Board of Regents of the University of Texas System · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 12152027

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 12150445

    Method and composition for hypothermic storage of placental tissue

    Prime Merger Sub, LLC · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 12151001

    Optimized expression cassettes for gene therapy

    Tenaya Therapeutics, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 12152028

    Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators

    Corcept Therapeutics Incorporated · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 12152244

    Selective antisense compounds and uses thereof

    Ionis Pharmaceuticals, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 12150957

    Trace element compositions, methods of making and use

    American Regent, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 12152067

    Human antibodies to ebola virus glycoprotein

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 12152061

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 12152270

    Neurotransmitter transport in probiotics

    Regents of the University of Minnesota · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 12152007

    Substituted heterocycles as c-MYC targeting agents

    Northwestern University · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 12150998

    Bicyclic peptide ligands specific for P-selectin

    BicycleTx Limited · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 12151062

    Compositions and devices to administer pharmaceutical compositions nasally

    The Board of Regents of the University of Texas System · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 12150995

    IRAK degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 12151024

    Manufacturing of bupivacaine multivesicular liposomes

    Pacira Pharmaceuticals, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 12151998

    Solid drug form of N-(2,6-bis(1-methylethyl)phenyl)-N′-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea hydrochloride and compositions, methods and kits related thereto

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 12150777

    Treatment of depression

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 12150956

    Trace element compositions, methods of making and use

    American Regent, Inc. · Granted Tue Nov 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. WO 2024243450

    MÉTHODES DE TRAITEMENT UTILISANT DES CONJUGUÉS ANTICORPS-MÉDICAMENT ANTI-C-MET

    ABBVIE INC [US] · Granted Thu Nov 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 2024390317

    COMBINATION TREATMENT AND/OR PREVENTION OF CARDIAC DISEASES IN NON-HUMAN MAMMALS COMPRISING ONE OR MORE SGLT-2 INHIBITORS AND PIMOBENDAN AND/OR TELMISARTAN

    BOEHRINGER INGELHEIM VETMEDICA GMBH [DE] · Granted Thu Nov 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 2024390332

    Combination treatment and/or prevention of renal diseases and/or hypertension in non-human mammals comprising one or more SGLT-2 inhibitors and telmisartan

    BOEHRINGER INGELHEIM VETMEDICA GMBH [DE] · Granted Thu Nov 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 2024390367

    METHODS OF TREATING VITILIGO WITH UPADACITINIB

    ABBVIE INC [US] · Granted Thu Nov 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. WO 2024242579

    RÉGIMES DE TRAITEMENT DE LA MALADIE DE PARKINSON IDIOPATHIQUE PRÉCOCE

    BIAL PORTELA & CA SA [PT] · Granted Thu Nov 28 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 23 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 12156903

    Use of ADAMTS13 for treating, ameliorating and/or preventing vaso-occlusive crisis in sickle cell disease, acute lung injury and/or acute respiratory distress syndrome

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 12156864

    Analogs of cyclobenzaprine and amitryptilene

    TONIX PHARMACEUTICALS HOLDING CORP · Granted Tue Dec 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 12156863

    Combination cancer therapy with pentaaza macrocyclic ring complex and ascorbate compound

    Galera Labs, LLC · Granted Tue Dec 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 12156880

    Heterocyclic RIP1 kinase inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Dec 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 12156877

    Methods of treating conditions related to a thiamine deficiency, a thiamine-dependent enzyme, or an associated cofactor

    The Regents of the University of California · Granted Tue Dec 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 12156931

    Organic counteranion co-assembly strategy for the formation of cyclodextrin-containing hybrid frameworks

    Northwestern University · Granted Tue Dec 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 28 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.