Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11801269

    Compositions and methods for transplantation of colon microbiota

    Regents of the University of Minnesota · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11802158

    Bispecific anti-CD3 antibodies, bispecific activatable anti-CD3 antibodies, and methods of using the same

    CytomX Therapeutics, Inc. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11801234

    Methods of treating APOL-1 dependent focal segmental glomerulosclerosis

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11802279

    Modified L-asparaginase

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11802292

    Modified orthopoxvirus vectors

    TURNSTONE BIOLOGICS CORP. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11802272

    Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations

    The Board of Regents of the University of Texas System · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11802237

    Method for producing powder containing zirconia particles and fluorescent agent

    KURARAY NORITAKE DENTAL INC. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11802110

    2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase

    Oxford Drug Design Limited · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11802138

    Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostic and therapeutic delivery

    The Regents of the University of California · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11801298

    MERS-CoV vaccine

    Inovio Pharmaceuticals, Inc. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11801295

    Immunogenic compositions and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11801288

    Cancer vaccines and methods of treatment using the same

    Inovio Pharmaceuticals, Inc. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11801296

    Development of a novel live attenuated African swine fever vaccine based in the deletion of gene A137R

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11801268

    Methods of treating ocular inflammation and chemical injuries of the eye with extracellular vesicles

    Capricor, Inc. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11801218

    Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine

    The Board of Regents of the University of Texas System · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11801241

    Muscarinic M2 receptor blockade to delay or prevent onset of progressive memory decline

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11801257

    Stimulation of an immune response by enantiomers of cationic lipids

    PDS Biotechnology Corporation · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11801229

    Molecular entrapment via homopolymer self-assembly

    Northwestern University · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11801265

    Preparation method of NK cells and use thereof in the treatment of cancer

    SINO UNITED (BEIJING) BIOMEDICAL TECHNOLOGY CO., LTD. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11802131

    Glutarimides for medical treatment

    C4 THERAPEUTICS, INC. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11802283

    Oligonucleotide analogues targeting human LMNA

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11802157

    Methods and compositions for modulating CAR-T activity

    Sana Biotechnology, Inc. · Granted Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 26 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11806406

    Virus-like particle conjugates for diagnosis and treatment of tumors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11806408

    Methods and compositions for treating cone-rod retinal dystrophy

    Editas Medicine, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11806353

    Methods of treating liver disorders or lipid disorders with a THR-beta agonist

    Madrigal Pharmaceuticals, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11806429

    Film formulations containing dexmedetomidine and methods of producing them

    BioXcel Therapeutics, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11806421

    Porous-cellulose particles and production method thereof, and cosmetic

    JGC Catalysts and Chemicals Ltd. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11806354

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11806504

    Device, system and methods for the oral delivery of therapeutic compounds

    Rani Therapeutics, LLC · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11806334

    Non-sedating dexmedetomidine treatment regimens

    BioXcel Therapeutics, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11807674

    Hepcidin analogues and uses thereof

    Protagonist Therapeutics, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11806337

    Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11806336

    Methods and compositions for treatment of epileptic disorders

    OVID THERAPEUTICS INC. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11806398

    Citrate buffered VEGF antagonist formulations

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11806432

    Compositions, methods and uses for thermally stable multi-targeted antigens

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11807646

    4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (USP19)

    ALMAC DISCOVERY LIMITED · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11807682

    M971 chimeric antigen receptors

    The United States of America, as represented by the Secretary, Department of Heath and Human Services · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11807853

    Soluble interleukin-7 receptor (sIL7R) modulating therapy to treat autoimmune diseases and cancer

    The Board of Regents of the University of Texas System · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11807649

    Fused tetracyclic quinazoline derivatives as inhibitors of ErbB2

    EnLiven Therapeutics, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11807658

    CD73 inhibitors

    ORIC PHARMACEUTICALS, INC. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11807638

    5- and 6-azaindole compounds for inhibition of Bcr-Abl tyrosine kinases

    Enliven Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11807644

    Methods and compounds for restoring mutant p53 function

    PMV PHARMACEUTICALS, INC. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11807661

    Antibody fusion protein and related compositions for targeting cancer

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11807689

    Anti-CD20 antibody compositions

    TG Therapeutics, Inc. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11807868

    Adeno-associated variants, formulations and methods for pulmonary delivery

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11807882

    Modified membrane type serine protease 1 (MTSP-1) polypeptides and methods of use

    Vertex Pharmaceuticals Incorporated · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11806385

    Biomarkers for monitoring immune transformation

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11806389

    Compositions and methods for treating central nervous system injury

    The United States Government as Represented by The Department of Veteran Affairs · Granted Tue Nov 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.