Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10093899

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10093900

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. WO 2018184678

    INHIBITEUR DES HDAC EN ASSOCIATION AVEC UN INHIBITEUR D'INTERACTION VEGF/VEGFR DESTINÉ À UN TRAITEMENT CONTRE LE CANCER BASÉ SUR LA NUMÉRATION PLAQUETTAIRE

    4SC AG [DE] · Granted Thu Oct 11 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 06 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10100021

    Crystalline(2S,4R)-5-(5′-chloro-2′-fluoro-[1,1′-biphenyl]-4-yl)-2-(ethoxymethyl)-4-(3-hydroxyisoxazole-5-carboxamido)-2-methylpentanoic acid and uses thereof

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10100018

    Amide derivatives as lysophosphatidic acid receptor antagonists

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10101331

    Methods of evaluating patients using E-cadherin or vimentin

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10100049

    JAK kinase inhibitor compounds for treatment of respiratory disease

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10100020

    Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases

    United Kingdom Research and Innovation · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10100012

    Compounds as anti-tubercular agents

    DRUG DISCOVERY RESEARCH CENTRE · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10098945

    Genetically engineered swine influenza virus and uses thereof

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10098887

    Antiviral compounds and methods of use thereof

    TRANA DISCOVERY, INC. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10098847

    Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10098866

    Pharmaceutical preparation containing copolyvidone

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10100317

    Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10100051

    Compound of 5-hydroxyl-1,7-naphthyridine substituted by aryloxy or heteroaryloxy, preparation method thereof and pharmaceutical use thereof

    Shenyang Sunshine Pharmaceutical Co., LTD · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10098894

    Transdermal cream

    Compass Therapeutics LLC · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10100089

    Process for the preparation of cyclic depsipeptides

    OnKure, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10098893

    Methods of administering a trace amine-associated receptor 1 (TAAR1) agonist to patients having the minor allele of the single nucleotide polymorphism rs2237457

    Northwestern University · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10098910

    Peroxide formulations and methods and applicators for using the same

    Aclaris Therapeutics, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10098889

    Complexes and salts of dihydropyrimidine derivatives and their application in pharmaceuticals

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10098878

    HIF-2α inhibitors for treating iron overload disorders

    The Board of Regents of the University of Texas System · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10098865

    Multi-arm polymeric prodrug conjugates of taxane-based compounds

    Nektar Therapeutics · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10098839

    Hydrogel toxin-absorbing or binding nanoparticles

    The Regents of the University of California · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10098540

    Hyperspectral imaging for detection of Parkinson's disease

    Regents of the University of Minnesota · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10098379

    Device and method for simulating chemosensation of smoking

    Sentiens, LLC · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10100279

    In vitro production of medial ganglionic eminence precursor cells

    The Regents of the University of California · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10098372

    Whitening composition and the use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10100310

    Modulation of prekallikrein (PKK) expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10100083

    Leukemia stem cell targeting ligands and methods of use

    The Regents of the University of California · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10100346

    Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10100367

    Diagnosing and monitoring CNS malignancies using microRNA

    The Regents of the University of California · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10098925

    Protein SLURP-1 for use in the treatment of ocular diseases

    Brightpulse Holding Ltd. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10098926

    Cell

    AUTOLUS LIMITED · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10098957

    Long-acting polymeric delivery systems

    Heron Therapeutics, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10098958

    Delivery of oligonucleotide functionalized nanoparticles

    Northwestern University · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10098959

    Method for synthesis of reactive conjugate clusters

    Ionis Pharmaceuticals, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10098971

    Library of pH responsive polymers and nanoprobes thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10099995

    Resveratrol esters

    Cole Research & Design, LLC · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10100013

    Crystalline freebase forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10100312

    Compositions and methods for inhibiting expression of TMPRSS6 gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Oct 16 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 11 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10105366

    Selective calcium channel antagonists

    Northwestern University · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10104882

    Methods and compositions for preventing and treating electrophile-mediated toxicities

    Montefiore Medical Center · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10106796

    Compound and method for treating myotonic dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10106620

    Blocking CD38 using anti-CD38 F(ab′)2 to protect NK cells

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10106616

    Antagonist antibodies to human prolactin receptor (PRLR)

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10106610

    Antibodies comprising chimeric constant domains

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10106592

    Interleukin-4 receptor-binding fusion proteins and uses thereof

    Medicenna Therapeutics Inc. · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10106503

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.