Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10086081

    Carbohydrate conjugated RNA agents and process for their preparation

    Alnylam Pharmaceuticals, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10087150

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10087229

    Peptide compound

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10087172

    Compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10087169

    Bicyclic PKM2 activators

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10087143

    Pyridone amides as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10087156

    Methods and compositions related to retinoid receptor-selective pathway

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10087148

    Quinazolines as biogenic amine transport modulators

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10086091

    Method of preparation of biodegradable nanoparticles with recognition characteristics

    The Board of Regents of the University of Texas System · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10086105

    Chitosan foam medical devices and methods

    Providence Health System—Oregon · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10086086

    Payload molecule delivery using molecular rebar

    MOLECULAR REBAR DESIGN, LLC · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10086088

    Neuronal specific targeting of caveolin expression to restore synaptic signaling and improve cognitive function in the neurodegenerative brain and motor function in spinal cord

    The Regents of the University of California · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10086084

    Activated polyoxazolines and conjugates and compositions comprising the same

    Serina Therapeutics, Inc. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10086041

    Syndecan-4 proteoliposomes for enhanced cutaneous wound healing and minimized inflammatory immune response

    The Board of Regents of the University of Texas System · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10086008

    Topical antifungal compositions and methods of use thereof

    REVOLUTION PHARMA LLC · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10085990

    Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors

    VTV THERAPEUTICS LLC · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10085998

    Salts of potassium ATP channel openers and uses thereof

    ESSENTIALIS, INC. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10085997

    Method of treating microbial infections

    The Regents of the University of California · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10085986

    Pyrimidinone compounds and their use

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10085951

    Curcuminoid formulations and related methods of treatment

    DESIGNS FOR HEALTH, INC. · Granted Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 27 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10093742

    Multispecific GITR-binding fusion proteins and methods of use thereof

    Inhibrx, Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10092504

    Use of cellular extracts for skin rejuvenation

    REGENICS AS · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10093629

    Heterocyclic compounds and their use as retinoid-related orphan receptor (ROR) gamma-T inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10092736

    Device and method for dispensing a drug

    Demira, Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10092656

    Protease inhibitors having enhanced features

    Nektar Therapeutics · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10092559

    Abuse resistant pharmaceutical compositions

    RECRO GAINESVILLE LLC · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10092637

    Dengue virus E-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10093641

    Process for making beraprost

    United Therapeutics Corporation · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10093676

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10093694

    Compounds for treating eye disorders or diseases

    The Regents of the University of California · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10093710

    Heterodimers of IL-15 and IL-15R alpha to increase thymic output and to treat lymphopenia

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10093698

    Peptide having efficacy for remedying hypopigmentation and inhibiting adipogenesis, and use of same

    CAREGEN CO., LTD. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10093686

    Heteroaryl inhibitors of PDE4

    Tetra Discovery Partners · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10093790

    Three-dimensional cellulose molded body, method for the production thereof and use of the same

    LENZING AKTIENGESELLSCHAFT · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10092598

    Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo

    RegenLab USA LLC · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10094836

    SLCO1B3 genotype

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10092593

    Citrate-rich calcium-magnesium supplement and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10093899

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10093900

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10092512

    Compositions and methods of making brittle-matrix particles through blister pack freezing

    The Board of Regents of the University of Texas System · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10092538

    Suppositories comprising cannabinoids

    AXIM BIOTECHNOLOGIES. INC. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10092580

    Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders

    The Regents of the University of California · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10092596

    Tungstate treatment of the dysbiosis associated with gastrointestinal inflammation

    The Regents of the University of California · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10093668

    Substituted aromatic N-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (Mnk1) and 2 (Mnk2)

    Northwestern University · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10093664

    Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease

    The Board of Regents of the University of Texas System · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10093684

    Substituted imidazo[1,2-a]pyrazines as Syk inhibitors

    GILEAD CONNECTICUT, INC. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10093708

    Interleukin-4 receptor-binding fusion proteins and uses thereof

    Medicenna Therapeutics Inc. · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10093745

    Anti-CSPG4 fusions with interferon for the treatment of malignancy

    The Regents of the University of California · Granted Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 04 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.