Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10035845

    Neutralizing antibodies to HIV-1 and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10035833

    Vascular endothelial growth factor antagonists and methods of making

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10035981

    Kidney-specific tumor vaccine directed against kidney tumor antigen G-250

    The Regents of the University of California · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10035848

    Antibody targeting cell surface deposited complement protein C3d and use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10035824

    Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases

    Protagonist Therapeutics, Inc. · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10035823

    Compositions for expanding regulatory T cells (TREG), and treating autoimmune and inflammatory diseases and conditions

    The Regents of the University of California · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10035761

    Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives

    REVIVA PHARMACEUTICALS, INC. · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. IL 259901

    Functionalized macrocycle chelators, complexes containing same and uses thereof as contrast agents

    BRACCO IMAGING SPA [IT] · Granted Tue Jul 31 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 26 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10039827

    Reoviruses having modified sequences

    ONCOLYTICS BIOTECH INC. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10039802

    Methods of treating chronic disorders with complement inhibitors

    Apellis Pharmaceuticals, Inc. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10039762

    Inhibitors of influenza viruses replication

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10039738

    Ulcer treatment

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10039807

    bFGF-polymer conjugates, methods for making the same and applications thereof

    The Regents of the University of California · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10039816

    Siderophore-based immunization against gram-negative bacteria

    The Regents of the University of California · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10039725

    Method for treating non-melanoma skin cancer by inducing UDP-glucuronosyltransferase activity using pterostilbene

    The Regents of the University of California · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10041936

    Neuronal cells cultured on microparticles and methods of using same

    The Regents of the University of California · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10039737

    Multi-arm polymeric alkanoate conjugates

    Nektar Therapeutics · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10039741

    Use of delta tocopherol for the treatment of lysosomal storage disorders

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10039761

    Co-crystals and pharmaceutical compositions comprising the same

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10040769

    HDAC inhibitors for the treatment of diabetic peripheral neuropathy

    Regenacy Pharmaceuticals, Inc. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10039818

    Attenuated pasteurella multocida strains

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10039775

    Preparation method for antitumor drug AP26113

    Suzhou Miracpharma Technology Co., Ltd. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10039819

    Attenuated Mannheimia haemolytica strains

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10040858

    Anti-CSF1R antibodies for treating PVNS

    Five Prime Therapeutics, Inc. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10040830

    Methods and compositions for protein delivery

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10040826

    Human immunodeficiency virus type 1 (HIV-1) N-terminal deleted GP120 immunogens

    The United States of America as represented by the Secretary of the Army · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10039729

    Use of kukoamine A and kukoamine B

    The First Affiliated Hospital, Third Military Medical University, PLA · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10039908

    Swallowable drug delivery device and method of delivery

    Rani Therapeutics, LLC · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10040799

    Substituted 4-methyl-pyrrolo[1,2-A]pyrimidine-8-carboxamide compounds and uses thereof for modulating glucocerebrosidase activity

    Northwestern University · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10041053

    Rationally-designed single-chain meganucleases with non-palindromic recognition sequences

    Precision BioSciences, Inc. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10041041

    Compositions and methods for treating retinal diseases

    The Regents of the University of California · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10040766

    Ubiquitination inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Aug 07 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 02 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10045941

    Method for formulating large diameter synthetic membrane vesicles

    Pacira Pharmaceuticals, Inc. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10047401

    Expression protein-coding and noncoding genes as prognostic classifiers in early stage lung cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10047396

    Biomarkers for diagnosis of transient ischemic attacks

    The Regents of the University of California · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10047361

    Disulfide-containing alkyne linking agents

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10047330

    Alcoholic compositions having a lowered risk of acetaldehydemia

    Deuterla Beverages, LLC · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10047160

    Anti-EGFRvIII antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10047148

    Neutralizing GP41 antibodies and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10047147

    Neutralizing GP41 antibodies and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10047125

    Peptide having activity to improve skin condition and use thereof

    CAREGEN CO., LTD. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10047153

    Human antibodies to Fel d1 and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10047104

    Bicyclic heterocyclyl derivatives as IRAK4 inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10047095

    sGC stimulators

    IRONWOOD PHARMACEUTICALS, INC. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10047028

    Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses

    Esperion Therapeutics, Inc. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10046057

    Methods for arranging and packing nucleic acids for unusual resistance to nucleases and targeted delivery for gene therapy

    The Regents of the University of California · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10046036

    Chemically modified cystathionine β-synthase enzyme for treatment of homocystinuria

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10046028

    Methods and compositions for modulating PD1

    Sangamo Therapeutics, Inc. · Granted Tue Aug 14 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.