Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10000551

    Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same

    Protalix Ltd. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9999369

    Laser-scribed ferrogel sensor with magnetic particles

    Regents of the University of Minnesota · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10000525

    Non-hormonal steroid modulators of NF-κB for treatment of disease

    ReveraGen BioPharma, Inc. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10000556

    Single-domain VHH antibodies directed to norovirus GI.1 and GII.4 and their use

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10000582

    Ethylsulfonated hyaluronic acid biopolymers and methods of use thereof

    The Regents of the University of California · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9999673

    PEGylated lipids and their use for drug delivery

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10001495

    Blood factor monitoring assay and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10000523

    β-D-2′-deoxy-2′-α-fluoro-2′-β-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment

    Atea Pharmaceuticals, Inc. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10000813

    Method of diagnosing and treating cancer using B-catenin splice variants

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10000746

    LAGLIDADG homing endonuclease cleaving the T cell receptor alpha gene and uses thereof

    PRECISION GENOME ENGINEERING, INC. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10001483

    Methods for the treatment of Kaposi's sarcoma or KSHV-induced lymphoma using immunomodulatory compounds, and uses of biomarkers

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10000534

    Peptide having osteoblast proliferation activity and periodontal ligament fibroblast proliferation activity, and use of same

    CAREGEN CO., LTD. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10000564

    Methods of treating an inflammatory condition or sensitivity to an allergen with anti-IL-33 antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10000477

    Dopamine D3 receptor antagonist compounds

    Indivior UK Limited · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10000753

    Age-related macular degeneration treatment

    Benitec Biopharma Limited · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10000772

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10000488

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10001485

    Methods for sensitizing a quiescent cancer stem cell to a BCR-ABL inhibitor

    The Regents of the University of California · Granted Tue Jun 19 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 14 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 2018169113

    HIGH CONCENTRATION FORMULATION

    CASSIOPEA S P A [IT] · Granted Thu Jun 21 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 16 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10005810

    Process for preparing nucleoside prodrugs

    University College Cardiff Consultants Limited · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10005815

    Biologically cleavable tetrapeptide linking agents

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10005745

    Amyloid targeting agents and methods of using the same

    The Regents of the University of California · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10005741

    Therapeutic compounds

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10004704

    Compositions and methods for treating chronic inflammation and inflammatory diseases

    Infirst Healthcare Limited · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10005743

    Methods for producing viloxazine salts and novel polymorphs thereof

    Supernus Pharmaceuticals, Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10005771

    Bicyclic derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activities

    Almirall, S.A. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10006025

    Compositions and methods for inhibiting gene expression of alpha-1 AntiTrypsin

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10005724

    Therapeutic compounds and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10006052

    Laglidadg homing endonuclease cleaving the C-C chemokine receptor type-5 (CCR5) gene and uses thereof

    PRECISION GENOME ENGINEERING, INC. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10004702

    Linear guanidine derivatives, methods of preparation and uses thereof

    LEAD DISCOVERY SIENA S.R.L. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10004782

    Glucokinase activator compositions for the treatment of diabetes

    VTV THERAPEUTICS LLC · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10004806

    Periodontal regeneration composition and method of using same

    Periovance, Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10005735

    Inhibitors of RPN11

    The Regents of the University of California · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10005740

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10004775

    Inhibition of hypoxia-inducible factor activity with carica papaya extracts

    The Regents of the University of California · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10005670

    Calcium polyphosphate salt particles and method of making

    Sunny Delight Beverages Co. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10004800

    Antibody evolution immunogens

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10004783

    Method for delivering pramlintide into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10004785

    LKKTET and/or LKKTNT peptide compositions which are lyophilized or in a form capable of being lyophilized

    REGENERX BIOPHARMACEUTICALS, INC. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10004687

    Liposomal curcumin for treatment of diseases

    The Board of Regents of the University of Texas System · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10006924

    Method for differentially diagnosing ACTH-dependent cushing's syndrome

    Corcept Therapeutics Incorporated · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10004717

    Glycopyrrolate salts

    Dermira, Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10006080

    High-selectivity contact activation inhibitor based on infestin-4

    OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU “GEMATOLOGICHESKAYA KORPORATSIYA” · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10004751

    Compositions and methods for treating Dengue virus infection

    The Regents of the University of California · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10004691

    Orally disintegrable tablet

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10006031

    Antisense composition and method for treating muscle atrophy

    Sarepta Therapeutics, Inc. · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10005838

    Milk fat globule epidermal growth factor 8 regulates fatty acid uptake

    The Regents of the University of California · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10005833

    Methods of treating inflammation associated airway diseases and viral infections

    The Board of Regents of the University of Texas System · Granted Tue Jun 26 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.