Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2038

Annual patent cliff calendar for 2038 — US pharmaceutical patents by expiration date.

Patents
1,509

Quick answer

1,509 indexed pharmaceutical patents have expiration dates in 2038. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 9974796

    Inhibitors of the plasmodial surface anion channel as antimalarials

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 9974828

    Isoform nell-1 peptide

    The Regents of the University of California · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9974794

    Emulsion formulations of aprepitant

    Heron Therapeutics, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9974801

    Methods of treating and preventing diseases and disorders of the central nervous system

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 9974744

    Sustained release formulation of a non-steroidal anti-inflammatory drug

    Pacira Pharmaceuticals, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 9974785

    Aromatic heterocyclic derivatives and pharmaceutical applications thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 9974781

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 9974802

    Composition of novel carbohydrate drug for treatment of human diseases

    GALECTIN THERAPEUTICS, INC. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 9974789

    Substituted pyrazolopyrimidines as glucocerebrosidase activators

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 9974793

    Emulsion formulations of aprepitant

    Heron Therapeutics, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 9974853

    Immunoregulatory peptides and methods of use

    Compass Therapeutics LLC · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 9976130

    OPAA FL—a mutant enzyme with increased catalytic efficiency on organophosphorus compound GD

    The United States of America as represented by the Secretary of the Army · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 9975952

    Antibody fragments, compositions and uses thereof

    METIS PRECISION MEDICINE SB S.R.L. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 9975959

    Administration of kynurenine depleting enzymes for tumor therapy

    The Board of Regents of the University of Texas System · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 9975983

    Bio-reducible self-assembled liquid crystalline block copolymer for drug delivery

    UNIVERSITY OF CONNECTICUT · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 9976141

    Compositions and methods for inhibiting gene expression of Hif2alpha

    Arrowhead Pharmaceuticals, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 9976115

    Bone marrow adipose portion isolation device and methods

    Regenexx, LLC · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 9977033

    Methods for assessing cancer recurrence

    The Board of Regents of the University of Texas System · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 9976138

    Methods and compounds useful in conditions related to repeat expansion

    Ionis Pharmaceuticals, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 9975878

    Substituted triazine BMI-1 inhibitors

    PTC THERAPEUTICS, INC. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 9975925

    Influenza antigens and antibodies

    THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPT. HEALTH & HUMAN SERVICES · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 9975903

    Condensed heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 9975926

    Methods of making and using vaccines utilizing minicircle DNA expression vectors for production of foot-and-mouth-disease virus proteins and virus-like particles

    The United States of America, as represented by the Secretary of Homeland Security · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 9977021

    CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ tregs

    The Regents of the University of California · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 9975875

    Diamide compounds having muscarinic receptor antagonist and Beta2 adrenergic receptor agonist activity

    Theravance Respiratory Company, LLC · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 9977875

    Systems and methods of managing treatment of a chronic condition by symptom tracking

    Corcept Therapeutics Incorporated · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 9974742

    Emulsion formulations of an NK-1 receptor antagonist and uses thereof

    Heron Therapeutics, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 9974800

    Therapy for inhibition of single-stranded RNA virus replication

    RedHill Biopharma Ltd. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 9974844

    Cancer vaccine compositions and methods of using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 9975944

    Synthetic peptides for the treatment of autoimmune diseases

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 9975867

    Synthetic process for preparing 2-furoic acid derivatives

    Dermira, Inc. · Granted Tue May 22 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 17 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 9982000

    Pyrazole compounds and method for making and using the compounds

    Rigel Pharmaceuticals, Inc. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 9982260

    Identification of structurally similar small molecules that enhance therapeutic exon skipping

    The Regents of the University of California · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 9980924

    Topical pterostilbene compositions for use in treating UV-induced loss of barrier function in skin

    The Regents of the University of California · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 9980961

    Pyruvate kinase activators for use in therapy

    Agios Pharmaceuticals, Inc. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 9982265

    Inhibition of Bruton's tyrosine kinase (Btk) in the lung to treat severe lung inflammation and lung injury

    The Board of Regents of the University of Texas System · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 9981999

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 9982013

    Readily isolated bispecific antibodies with native immunoglobulin format

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 9982236

    Cell populations, methods of transdifferentiation and methods of use thereof

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 9981961

    Deoxycytidine kinase inhibitors

    The Regents of the University of California · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 9982259

    Transthyretin allele selective UNA oligomers for gene silencing

    ARCTURUS THERAPEUTICS, INC. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 9982025

    Monomeric griffithsin tandemers

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9982245

    Compositions for linking DNA-binding domains and cleavage domains

    Sangamo Therapeutics, Inc. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9981043

    Analgesic conjugates

    Regents of the University of Minnesota · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9981238

    Apparatus and methods for making nanosomes loaded with nucleic acid

    Aphios Corporation · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9981034

    Compositions and methods for vaccination against influenza A virus

    SOUTH DAKOTA BOARD OF REGENTS · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9981067

    Biomimetic hybrid gel compositions and methods of use

    BIOACTIVE REGENERATIVE THERAPEUTICS, INC. · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9980634

    Minimally-invasive measurement of esophageal inflammation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue May 29 2018 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 24 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2038?

1,509 published patents in our USPTO index have expiration dates falling in calendar year 2038.