Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2035

Annual patent cliff calendar for 2035 — US pharmaceutical patents by expiration date.

Patents
1,447

Quick answer

1,447 indexed pharmaceutical patents have expiration dates in 2035. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8987420

    High affinity human antibodies to human angiopoietin-2

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8986653

    Labeled iodinated tropane formulation

    Alseres Pharmaceuticals, Inc. · Granted Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8987454

    Azaindoles useful as inhibitors of JAK and other protein kinases

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 19 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8993598

    Pyrrole compounds

    Takeda Pharmaceutical Company Limited · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8993746

    Nuclease resistant double-stranded ribonucleic acid

    Alnylam Pharmaceuticals, Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8993627

    N-acetylcysteine amide (NAC amide) for the treatment of diseases and conditions associated with oxidative stress

    SENTIENT LIFESCIENCES, INC. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8993719

    Methods and compositions related to mutant Kunitz domain I of TFPI-2

    The Regents of the University of California · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8993626

    Methods of treatment using sterculic acid

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8993758

    Substituted quinoxalines and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8993752

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8993768

    Tropolone compounds for treating or preventing retroviral infection

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8993549

    Natural combination hormone replacement formulations and therapies

    Compass Therapeutics LLC · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8993585

    Cyclic amine substituted pyrimidinediamines as PKC inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8993548

    Natural combination hormone replacement formulations and therapies

    Compass Therapeutics LLC · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8992902

    N-maleimidyl polymer derivatives

    Nektar Therapeutics · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8992989

    Sustained-release formulations of topiramate

    Supernus Pharmaceuticals, Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8992906

    Compositions and methods for engraftment and increasing survival of adult muscle stem cells

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8992930

    Extracellular IFI16 as therapeutic agents

    University of Piemonte Orientale · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8993251

    Genes from 20q13 amplicon and their uses

    The Regents of the University of California · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8992886

    Cyclic peptide analogues for non-invasive imaging of pancreatic beta-cells

    The Board of Regents of the University of Texas System · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8992943

    Vaccine for protection against Shigella sonnei disease

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8993552

    Compositions and methods for treatment of leukemia

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8992944

    Purified Plasmodium and vaccine composition

    Sanaria Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8993266

    Proproteins activatable interferon alpha

    CytomX Therapeutics, Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8992894

    Oral stain remover and oral composition

    Regenetiss, Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8993519

    Method of treatment for neutropenia using stable formulations of recombinant human albumin-human granulocyte colony stimulating factor

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8993633

    Treatment of muscle disease characterized by insulin resistance

    Fate Therapeutics, (Canada) Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8993117

    Devices with multiple surface functionality

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8993600

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8993623

    Method for lowering cholesterol

    Phenomenome Discoveries Inc. · Granted Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 26 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. EP 2852409

    KOMBINATIONSTHERAPIE MIT ANTIKÖRPERN GEGEN CLAUDIN 18.2 ZUR BEHANDLUNG VON KREBS

    GANYMED PHARMACEUTICALS AG [DE] · Granted Wed Apr 01 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Mar 27 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8999349

    HMGB1-derived peptides enhance immune response to antigens

    The Regents of the University of California · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8999976

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8998846

    Drug releasing coatings for balloon catheters

    Lutonix, Inc. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8998847

    Drug releasing coatings for medical devices

    Lutonix, Inc. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8999351

    Lipids and compositions for the delivery of therapeutics

    Tekmira Pharmaceuticals Corporation · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8999294

    Nanoparticles for use in tumor diagnosis and therapy

    The Board of Regents of the University of Texas System · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8999638

    Method of treatment based on polymorphisms of the KCNQ1 gene

    VANDA PHARMACEUTICALS INC. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8999996

    Hydrazide containing nuclear transport modulators and uses thereof

    Karyopharm Therapeutics Inc. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8999934

    Treatment of astrocytes-tumor cells inhibitors of endothelin receptors

    The Board of Regents of the University of Texas System · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8999988

    Protein kinase inhibitors

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8999947

    Nucleic acid functionalized nanoparticles for therapeutic applications

    Northwestern University · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 9000020

    Linked dibenzimidazole antivirals

    Enanta Pharmaceuticals, Inc. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 9000025

    Autotaxin inhibitors and uses thereof

    AMIRA PHARMACEUTICALS, INC. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 9000143

    Compositions and methods for inhibiting expression of IKK-B gene

    Alnylam Pharmaceuticals, Inc. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 9000040

    Cross-linked fatty acid-based biomaterials

    ATRIUM MEDICAL CORPORATION · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 9000041

    Hydroxyl compounds and compositions for cholesterol management and related uses

    Esperion Therapeutics, Inc. · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 9000089

    Polyurea systems, processes for preparing the same and use thereof for postoperative adhesion barriers

    Medical Adhesive Revolution GmbH · Granted Tue Apr 07 2015 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 02 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2035?

1,447 published patents in our USPTO index have expiration dates falling in calendar year 2035.